What are the main applications of (2E)-3-(3-Pyridinyl)acrylic acid?

(2E)-3-(3-Pyridinyl)acrylic acid has several important applications.
One significant area is in the pharmaceutical industry.Pharmaceuticals is one of the most important areas. Compounds containing this structural unit can potentially be developed into drugs.Compounds containing the structural unit could be used to develop drugs. The pyridine ring and the acrylic acid moiety together offer unique chemical and biological properties.The pyridine ring, together with the acrylic acid moiety, offers unique chemical and biologic properties. For example, they can interact with specific biological targets in the body.They can, for example, interact with specific biological targets within the body. Some derivatives of (2E)-3-(3 -Pyridinyl)acrylic acid may exhibit anti - inflammatory properties.Some derivatives from (2E)-3 -(3-Pyridinyl-acrylic acid can have anti-inflammatory properties. By interacting with key enzymes or receptors involved in the inflammatory pathways, they can help to reduce inflammation.They can reduce inflammation by interacting with key receptors or enzymes involved in inflammatory pathways. In addition, it may have applications in treating certain neurodegenerative diseases.It may also be used to treat certain neurodegenerative disorders. The molecule's ability to penetrate cell membranes and interact with intracellular components makes it a promising candidate for developing drugs that can target the root causes of these diseases, such as abnormal protein aggregations.The molecule is a promising candidate to develop drugs that target the root cause of these diseases such as abnormal protein aggregates.

Another application is in the field of materials science.Another application is the field of materials sciences. (2E)-3-(3 -Pyridinyl)acrylic acid can be used as a monomer in the synthesis of polymers.As a monomer, (2E)-3 -(3-Pyridinyl-acrylic acid is useful in the synthesis and polymerization of polymers. The resulting polymers can have special properties due to the presence of the pyridine and acrylic acid groups.The presence of the pyridine groups and the acrylic acid groups can give the polymers special properties. The pyridine group can provide sites for coordination with metal ions, which can be useful in the preparation of metal - polymer complexes.The pyridine groups can act as sites for coordination of metal ions. This can be useful when preparing metal-polymer complexes. These complexes may find applications in catalysis, where the polymer - bound metal ions can act as efficient catalysts for various chemical reactions.These complexes can be used in catalysis where the metal ions bound to polymer can act as catalysts for different chemical reactions. The acrylic acid part can participate in polymerization reactions, allowing for the formation of polymers with different chain lengths and architectures.The acrylic acid can be used in polymerization reactions to form polymers of different chain lengths and structures. These polymers can be used in coatings, where they can provide good adhesion to substrates and also offer some degree of chemical resistance.These polymers are used in coatings where they provide good adhesion and chemical resistance.

It also has applications in the synthesis of fluorescent dyes.It can also be used to synthesize fluorescent dyes. The structure of (2E)-3-(3 -Pyridinyl)acrylic acid can be modified to introduce fluorescent properties.It is possible to modify the structure of (2E-3)-3-(3-Pyridinyl-acrylic acid in order to introduce fluorescent properties. The pyridine ring and the conjugated double - bond system of the acrylic acid can contribute to the fluorescence mechanism.The pyridine ring, and the conjugated double-bond system of the acrylic acids can contribute to the mechanism of fluorescence. These fluorescent dyes can be used in biological imaging.These fluorescent dyes are useful for biological imaging. They can be labeled to specific biomolecules, such as proteins or nucleic acids, allowing researchers to track the movement and behavior of these biomolecules within cells.They can be labeled with specific biomolecules such as proteins or nucleic acid, allowing researchers track the movement and behaviour of these biomolecules inside cells. In environmental monitoring, these dyes can be used to detect certain pollutants.These dyes can be used in environmental monitoring to detect pollutants. Their fluorescence can change in the presence of specific contaminants, providing a simple and sensitive method for pollution detection.Their fluorescence changes in the presence specific contaminants. This is a simple, sensitive method of pollution detection. Overall, (2E)-3-(3 -Pyridinyl)acrylic acid is a versatile compound with a wide range of applications across different scientific and technological fields.The (2E)-3 -(3-Pyridinyl-)acrylic acid has a variety of uses in different scientific and technical fields.

What are the physical and chemical properties of (2E)-3-(3-Pyridinyl)acrylic acid?

(2E)-3-(3 - Pyridinyl)acrylic acid is an organic compound with distinct physical and chemical properties.The organic compound (2E)-3(3-pyridinyl)acrylic is a compound with distinct physical, chemical and physical properties.
Physical properties:Physical Properties
Appearance: It is typically a solid under normal conditions.Appearance: Under normal conditions, it is usually a solid. The solid might exist in a crystalline form, which can be determined through techniques like X - ray crystallography.The solid may exist in a crystallized form, which is determined by techniques such as X-ray crystallography. Crystalline solids often have a regular and ordered arrangement of molecules, contributing to their characteristic appearance, such as well - defined shapes and smooth surfaces.Crystalline solids have an ordered and regular arrangement of molecules that contributes to their characteristic appearance.
Color: It usually has a white to off - white color.Color: It is usually white or off-white. This relatively light color is common for many organic acids that do not contain highly conjugated or chromophoric groups in large numbers.This color is common in many organic acids, especially those that don't contain a large number of highly conjugated or chromophoric group. A lack of extensive conjugation in the molecule results in absorption of light mainly in the ultraviolet region, making it appear colorless or pale in the visible light spectrum.Lack of extensive conjugation results in absorption mainly in ultraviolet region. This makes the molecule appear colorless or pale.
Melting point: The melting point of (2E)-3-(3 - Pyridinyl)acrylic acid is an important physical property.Melting point: The melting of (2E)-3 -(3- Pyridinyl-acrylic acid) is an important property. It represents the temperature at which the solid transitions to the liquid state.It is the temperature at the liquid-solid transition. Precise determination of the melting point can be used for purity assessment.The melting point can be used to determine purity. Impurities in the compound usually lower and broaden the melting point range.Impurities in a compound lower and widen the melting point range. By measuring the melting point accurately, one can ensure the quality of the synthesized or purified sample.By measuring the melting points accurately, one can guarantee the quality of the synthesized sample or purified sample.
Solubility: In terms of solubility, it shows some interesting behavior.Solubility: It shows an interesting behavior in terms of solubility. It is sparingly soluble in non - polar solvents such as hexane or toluene.It is only sparingly soluble with non-polar solvents like hexane and toluene. This is because the molecule has a polar carboxylic acid group and a polar pyridine ring, while non - polar solvents lack the ability to interact favorably with these polar moieties through dipole - dipole or hydrogen - bonding interactions.This is due to the fact that the molecule contains a polar carboxylic group and a non-polar pyridine ring. Non-polar solvents are unable to interact with these polar moieties via dipole-dipole or hydrogen-bonding interactions. However, it has better solubility in polar solvents like ethanol, methanol, or dimethyl sulfoxide (DMSO).It is more soluble in polar solvents such as ethanol, methanol or dimethyl sulfoxide. The polar solvents can form hydrogen bonds with the carboxylic acid group and interact with the pyridine ring through dipole - dipole forces, facilitating dissolution.The polar solvents interact with the pyridine rings through dipole-dipole forces and can form hydrogen bonds.

Chemical properties:Chemical properties
Acidity: The carboxylic acid group in (2E)-3-(3 - Pyridinyl)acrylic acid gives it acidic properties.Acidity: The carboxylic group in (2E-3)-3-(3-pyridinyl)acrylic gives it acidic characteristics. It can donate a proton (H+) in the presence of a base.It can donate a proton (H+) when a base is present. The acidity constant (pKa) of the carboxylic acid group can be determined experimentally.Experimentally, the acidity constant (pKa), of a carboxylic acid can be determined. The presence of the pyridine ring can have an influence on the acidity.The presence of a pyridine ring may influence the acidity. The electron - withdrawing effect of the pyridine ring can stabilize the carboxylate anion formed after deprotonation, potentially increasing the acidity of the carboxylic acid group compared to a simple aliphatic carboxylic acid.The electron-withdrawing effect of pyridine can stabilize the carboxylate anion formed after deprotonation. This could increase the acidity of a carboxylic group compared to simple aliphatic carboxylic acids.
Reactivity towards nucleophiles: The double bond in the acrylic acid part of the molecule is reactive towards nucleophiles.Reactivity towards nucleophiles The double bond in acrylic acid part of molecule is reactive toward nucleophiles. Nucleophilic addition reactions can occur across the double bond.Nucleophilic reactions can occur across a double bond. For example, a strong nucleophile like a Grignard reagent can add to the double bond, forming a new carbon - carbon bond.Grignard reagent, for example, is a strong nucleophile that can add to a double bond and form a new carbon-carbon bond. This reactivity is due to the electrophilic nature of the double bond, which is polarized by the adjacent carbonyl group of the carboxylic acid.This reactivity occurs because the double bond is electrophilic and is polarized with the carbonyl group adjacent to it.
Reactivity towards electrophiles: The pyridine ring can also participate in reactions with electrophiles.Reactivity towards Electrophiles: the pyridine ring is also capable of participating in reactions with electrophiles. The nitrogen atom in the pyridine ring has a lone pair of electrons, which can make the ring slightly nucleophilic in certain reaction conditions.The nitrogen atom of the pyridine rings has a single pair of electrons. This can make the ring nucleophilic under certain conditions. Electrophilic aromatic substitution reactions can take place on the pyridine ring, where an electrophile replaces a hydrogen atom on the ring.On the pyridine rings, electrophilic aromatic substitutions can occur. An electrophile will replace a hydrogen on the ring. These reactions are important for functionalizing the molecule and introducing new substituents for further synthetic applications.These reactions are crucial for functionalizing a molecule and adding new substituents to further syntheses.

How is (2E)-3-(3-Pyridinyl)acrylic acid synthesized?

(2E)-3-(3-Pyridinyl)acrylic acid can be synthesized through the following general approach.
One common method involves a Knoevenagel condensation reaction.Knoevenagel condensation is a common method. First, 3 - pyridinecarboxaldehyde is selected as a starting material. This aldehyde contains the pyridine ring which is an essential part of the target molecule.This aldehyde has the pyridine ring, which is a key component of the target molecule. Another key reagent is malonic acid.Malonic acid is another key reagent. In the presence of a suitable base catalyst, such as piperidine, the reaction can proceed.The reaction can be carried out in the presence of a base catalyst such as piperidine.

The reaction mechanism begins with the deprotonation of malonic acid by the base.The reaction begins with the deprotonation by the base of malonic acid. The resulting enolate anion then attacks the carbonyl carbon of 3 - pyridinecarboxaldehyde. This forms an intermediate.This forms an intermediary. Subsequently, a series of proton transfers and elimination reactions occur.Then, a series proton transfer and elimination reactions take place. The elimination step leads to the formation of the double bond, giving rise to (2E)-3-(3 - pyridinyl)acrylic acid along with the liberation of carbon dioxide from malonic acid.The elimination step results in the formation of a double bond and the liberation carbon dioxide from malonic acids.

The reaction is typically carried out in a suitable solvent, like ethanol or a mixture of solvents, which helps in dissolving the reactants and facilitating the reaction.The reaction is usually carried out in a solvent like ethanol, or a mixture, which helps dissolve the reactants, and facilitates the reaction. After the reaction is complete, the product can be isolated through several purification steps.The product can be isolated after the reaction has been completed by a series of purification steps. This may include techniques such as recrystallization.This can include techniques like recrystallization. Recrystallization can be done by dissolving the reaction mixture in a hot solvent in which the product has a certain solubility.Recrystallization is possible by dissolving a reaction mixture in a solvent that has a high solubility for the product. As the solution cools, the (2E)-3-(3 - pyridinyl)acrylic acid crystallizes out, leaving impurities in the solution.As the solution cools down, the (2E-3)-3-(3-pyridinyl-acrylic acid crystallizes and leaves impurities behind. Filtration can then be used to separate the solid product from the remaining liquid.Filtration is then used to separate the solid from the liquid.

Another possible route could involve using other aldehyde - based condensation reactions with appropriate modifications to introduce the pyridine moiety and form the acrylic acid structure.Another route would be to use other aldehyde-based condensation reactions, with modifications, to introduce the pyridine ring and form the acrylic acids. However, the Knoevenagel condensation is a relatively straightforward and commonly used method for the synthesis of this type of a,b - unsaturated carboxylic acid containing a pyridine ring.Knoevenagel condensation, however, is a simple and widely used method to synthesize this type of ab - unsaturated pyridine carboxylic acid. Care must be taken during the reaction to control reaction conditions such as temperature, reaction time, and reagent stoichiometry to ensure good yields and purity of the final product.To ensure high yields and purity, it is important to carefully control the reaction conditions, such as temperature, time and reagent ratio, during the reaction.

What is the stability and shelf life of (2E)-3-(3-Pyridinyl)acrylic acid?

(2E)-3-(3 - Pyridinyl)acrylic acid is a type of organic compound.The organic compound (2E)-3(3-pyridinyl)acrylic is a type.
Stability:
In general, (2E)-3-(3 - Pyridinyl)acrylic acid is relatively stable under normal conditions when stored properly.When stored correctly, (2E - 3-(3-pyridinyl)acrylic acids is generally stable. It is an organic acid, and like many organic acids, it can be affected by factors such as heat, light, and humidity.Like many organic acids it can be affected adversely by factors like heat, light and humidity. Heat can potentially cause decomposition or chemical reactions.Heat can cause chemical reactions or decomposition. If exposed to high temperatures for an extended period, the molecule may break down, perhaps through processes like decarboxylation.The molecule may decompose if exposed to high temperatures over a long period of time, possibly through processes such as decarboxylation. However, when kept at room temperature, it remains relatively stable.When kept at room temperatures, it remains relatively inert.

Light can also have an impact.Light can also impact. Prolonged exposure to light, especially ultraviolet light, can initiate photochemical reactions that may lead to changes in its chemical structure.Long-term exposure to ultraviolet light can cause photochemical reactions, which may change the chemical structure. For example, light - induced isomerization could potentially occur, although the exact nature of such reactions would depend on the specific energy of the light and the environment.Light-induced isomerization, for example, could occur, but the exact nature of these reactions would depend on both the specific energy and environment of the light.

Humidity can be a concern as well.Humidity is also a problem. Since it is an acid, it may absorb moisture from the air.It is an acid and may absorb moisture in the air. In the presence of water, hydrolysis reactions could potentially take place, although this is less likely for this particular compound compared to some more reactive esters or amides.Hydrolysis reactions may occur in the presence of moisture, but this is less likely to happen for this compound than it is for some esters or amides that are more reactive. Overall, it is best stored in a dry environment to avoid any potential issues related to water - induced reactions.It is best to store it in a dry place to avoid any issues that may arise from water-induced reactions.

Shelf life:Shelf life
The shelf life of (2E)-3-(3 - Pyridinyl)acrylic acid can vary depending on storage conditions.Storage conditions can affect the shelf life of (2E-3)-3-(3-Pyridinyl-Acrylic Acid. Under ideal storage conditions - in a cool, dark, and dry place, in a properly sealed container - it can have a relatively long shelf life, potentially several years.It can have a long shelf life under ideal conditions, such as in a cool and dark place, with a tightly sealed container. However, if the storage conditions deviate from these ideals, the shelf life will be shortened.If the storage conditions are not ideal, the shelf-life will be reduced.
If stored at elevated temperatures, say above 30 - 40 degrees Celsius, the rate of any potential decomposition reactions will increase, and the shelf life could be reduced to months.If the compound is stored at high temperatures (above 30-40 degrees Celsius), the rate of decomposition reactions can increase and the shelf-life could be reduced by months. Similarly, if exposed to continuous bright light or high humidity environments, the compound may start to degrade more rapidly.The compound can also degrade faster if it is exposed to high humidity or bright light for long periods of time. For example, in a humid storage area with a relative humidity of over 70%, the absorption of water might accelerate any chemical changes, and the shelf life could be significantly shorter, perhaps less than a year.In a humid area with a relative moisture of more than 70%, water absorption could accelerate any chemical changes and the shelf-life of the compound could be considerably shorter, perhaps even less than one year. In a research or industrial setting, it is advisable to regularly check the quality of the compound, for instance, by performing analytical tests such as HPLC (High - Performance Liquid Chromatography) to determine its purity and ensure that it is still suitable for use.In a laboratory or industrial setting, it's important to check the quality of a compound regularly. For example, you can perform analytical tests like HPLC (High-Performance Liquid Chromatography), to determine its purity, and to ensure that it's still suitable for use.

Are there any safety precautions when handling (2E)-3-(3-Pyridinyl)acrylic acid?

(2E)-3-(3-Pyridinyl)acrylic acid is a chemical compound that requires certain safety precautions during handling.
First, when working with this substance, proper personal protective equipment should be worn.Wear the appropriate personal protective equipment when working with this substance. This includes safety goggles to protect the eyes from any potential splashes.Safety goggles are recommended to protect your eyes from any possible splashes. Chemical - resistant gloves made of materials like nitrile or neoprene should be used to prevent skin contact.To prevent skin contact, chemical-resistant gloves made from materials such as nitrile and neoprene are recommended. Skin exposure could potentially lead to irritation, allergic reactions, or absorption of the chemical into the body, which may cause harm to internal organs over time.Skin contact could cause irritation, allergic reactions or absorption of chemicals into the body. This can lead to organ damage over time. A lab coat or other protective clothing is also necessary to shield the body from spills.To protect the body from spills, a lab coat or other protective clothing may be required.

In the workplace, ensure good ventilation.Assure good ventilation in the workplace. This compound may release vapors or dust particles, and a well - ventilated area helps to prevent the build - up of these substances in the air.A well-ventilated area will help to prevent the build-up of these substances. If possible, work in a fume hood.If possible, use a fume-hood. A fume hood effectively captures and exhausts any potentially harmful fumes, reducing the risk of inhalation.A fume hood will effectively capture and exhaust any potentially harmful fumes reducing the risk for inhalation. Inhalation of (2E)-3-(3 - Pyridinyl)acrylic acid particles or vapors can irritate the respiratory tract, causing coughing, shortness of breath, or more serious long - term lung problems.Inhaling (2E)-3 - (3 - Pyridinyl )acrylic acid particles and vapors may cause irritation of the respiratory tract. This can lead to coughing, shortness or breath, as well as more serious lung problems.

When handling the chemical, be careful to avoid creating dust.Avoid creating dust when handling the chemical. Grinding, crushing, or vigorously shaking containers can cause dust to become airborne.Dust can be released into the air when containers are crushed, shook vigorously, or ground. If you need to transfer the substance, do it slowly and carefully to minimize the generation of dust.Transferring the substance slowly and carefully will minimize the dust.

In case of contact with the skin, immediately wash the affected area with plenty of water for at least 15 minutes.If the chemical gets into the eyes, rinse them thoroughly with running water for a long time. If the chemical gets into the eyes, rinse them thoroughly with running water for an extended period and seek immediate medical attention.If the chemical gets in the eyes, rinse the eyes thoroughly with running water and seek immediate medical care. In the event of inhalation, move to an area with fresh air and, if symptoms such as difficulty breathing persist, call for emergency medical help.In the case of inhalation move to a fresh area and call emergency medical assistance if symptoms persist such as difficulty breathing.

Proper storage is also crucial.The right storage is also important. Store (2E)-3-(3 - Pyridinyl)acrylic acid in a cool, dry place away from heat sources, open flames, and incompatible substances.Store (2E-3)-3-(3-Pyridinyl-acrylic acid) in a cool and dry place, away from heat sources, flames, or incompatible substances. Keep it in a tightly sealed container to prevent the release of vapors and to protect it from moisture, which could potentially affect its chemical properties.Keep it in a tightly-sealed container to prevent vapors from escaping and to protect the chemical properties.