| product_name | (2E)-3-(4-Chloro-3-nitrophenyl)acrylic acid |
| CAS_number | 3443-06-3 |
| formula | C9H6ClNO4 |
| molar_mass | 227.6 |
| property_1 | yellow crystalline powder |
| property_2 | melting_point: 260-262 °C |
| property_3 | solubility: slightly soluble in water |
| property_4 | density: 1.5 g/cm³ |
| property_5 | stability: stable under normal temperatures and pressures |
| property_6 | boiling_point: decomposes |
| property_7 | pKa: 3.8 |
| property_8 | logP: 2.26 |
| property_9 | hazard_statements: H315, H319, H335 |
| property_10 | signal_word: Warning |
What is (2E)-3-(4-Chloro-3-nitrophenyl)acrylic acid and what are its uses in various
industries?
(2E)-3-(4-Chloro-3-nitrophenyl)acrylic acid, also known as CCPA, is a
chemical compound that is widely used in the pharmaceutical, agricultural, and chemical
industries. It is primarily used as an intermediate in the synthesis of various organic
compounds, including pharmaceutical drugs, agrochemicals, and specialty chemicals. CCPA is
known for its versatility and unique chemical properties, making it a valuable compound in
numerous applications.
What are the key characteristics and properties of
(2E)-3-(4-Chloro-3-nitrophenyl)acrylic acid that make it beneficial for industrial
use?
CCPA is a crystalline solid that is highly stable under normal conditions. It
has a molecular formula of C9H6ClNO4 and a molecular weight of 229.6 g/mol. The compound is
insoluble in water but soluble in organic solvents, making it easy to handle and work with
in various chemical processes. Additionally, CCPA exhibits good thermal stability, ensuring
its effectiveness in high-temperature reactions. Its unique structure and chemical
properties make it an ideal intermediate for the synthesis of complex organic
compounds.
How is (2E)-3-(4-Chloro-3-nitrophenyl)acrylic acid synthesized, and what
are the key steps involved in its production?
CCPA is typically synthesized through a
series of chemical reactions starting from simple starting materials. One common synthetic
route involves the condensation of 4-chloro-3-nitrobenzaldehyde with malonic acid in the
presence of a suitable catalyst. The resulting product is then subjected to various
purification steps to obtain high-purity CCPA. The key steps in the production of CCPA
include condensation, cyclization, and purification processes, ensuring the quality and
purity of the final product.
What are the main applications of
(2E)-3-(4-Chloro-3-nitrophenyl)acrylic acid in the pharmaceutical industry?
CCPA is
widely used as an intermediate in the synthesis of pharmaceutical drugs, particularly
nonsteroidal anti-inflammatory drugs (NSAIDs) and antibacterial agents. The compound serves
as a key building block in the production of active pharmaceutical ingredients (APIs) due to
its ability to undergo various functional group transformations. CCPA is essential for the
development of new drug candidates and plays a crucial role in drug discovery and
development processes in the pharmaceutical industry.
How does
(2E)-3-(4-Chloro-3-nitrophenyl)acrylic acid contribute to the agricultural sector and the
production of agrochemicals?
CCPA is an important intermediate in the synthesis of
agrochemicals, including herbicides, insecticides, and fungicides. The compound is used to
create active ingredients that target specific pests and diseases affecting crops, ensuring
higher yields and improved crop quality. CCPA's unique chemical structure allows for the
modification of its properties to develop potent and effective agrochemical products that
help protect crops from various threats. Its role in agricultural chemistry underscores its
significance in sustainable farming practices.
What advantages does
(2E)-3-(4-Chloro-3-nitrophenyl)acrylic acid offer in the chemical industry and the
production of specialty chemicals?
CCPA is valued in the chemical industry for its
versatility and wide range of applications in the synthesis of specialty chemicals. The
compound's reactivity and functional group compatibility allow for the creation of complex
chemical structures that have specific properties and functions. CCPA is used to produce
specialty chemicals such as dyes, pigments, and polymers, serving various industrial sectors
such as textiles, coatings, and plastics. Its unique characteristics make it a valuable
component in the development of innovative chemical products with diverse
applications.
What safety considerations should be taken into account when handling
(2E)-3-(4-Chloro-3-nitrophenyl)acrylic acid in industrial settings?
When working with
CCPA, it is essential to follow proper safety procedures to minimize the risks associated
with handling chemical compounds. Protective equipment, including gloves, goggles, and lab
coats, should be worn to prevent skin contact and inhalation of CCPA vapors. The compound
should be stored in a well-ventilated area away from heat sources and incompatible materials
to avoid accidents or chemical reactions. In case of exposure or ingestion, immediate
medical attention should be sought to address any health concerns. Adhering to strict safety
protocols ensures a safe working environment when using CCPA in industrial
settings.
How does the purity and quality of (2E)-3-(4-Chloro-3-nitrophenyl)acrylic
acid impact its performance in various applications?
The purity and quality of CCPA
are crucial factors that determine its effectiveness and performance in industrial
applications. High-purity CCPA ensures consistency in chemical reactions and product
quality, leading to reliable results and desirable outcomes. Impurities or contaminants in
CCPA can affect reaction efficiency, product yield, and overall process stability.
Therefore, it is essential to use high-quality CCPA from reputable suppliers to maximize its
performance and achieve superior results in pharmaceutical, agricultural, and chemical
applications.
What role does (2E)-3-(4-Chloro-3-nitrophenyl)acrylic acid play in the
development of new materials and innovative technologies?
CCPA is a key component in
the synthesis of novel materials and technologies that drive innovation in various
industries. The compound's unique chemical structure and properties enable researchers and
engineers to design advanced materials with specific characteristics and functions. CCPA
serves as a fundamental building block for developing new polymers, catalysts, and
electronic materials that have applications in diverse fields such as nanotechnology,
materials science, and renewable energy. Its contribution to the development of cutting-edge
technologies underscores its importance in pushing the boundaries of scientific discovery
and technological advancement.
