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Product Name | (2E)-3-Ethoxyacrylic acid |
Cas Number | 2465-65-8 |
Formula | C5H8O3 |
Molar Mass | 116.12 g/mol |
Density | Not available |
Melting Point | Not available |
Boiling Point | Not available |
Solubility | Not available |
Vapor Pressure | Not available |
Flash Point | Not available |
Refractive Index | Not available |
Pka | Not available |
Appearance | Not available |
Odor | Not available |
What are the applications of (2E)-3-ethoxyacrylic acid?
(2E)-3-ethoxyacrylic acid is a compound with several notable applications.The (2E)-3 -ethoxyacrylic is a compound that has several notable applications.
In the field of organic synthesis, it serves as a valuable building block.It is a useful building block in organic synthesis. Its unsaturated double bond and the ethoxy - carboxyl functional groups make it reactive in various chemical reactions.Its double bond is unsaturated and its ethoxy-carboxyl functional groups make this compound reactive in many chemical reactions. For instance, it can participate in Michael addition reactions.It can, for example, participate in Michael additions. The electron - withdrawing nature of the carboxyl group activates the double bond, allowing it to react with nucleophiles such as amines, thiols, and enolates.The electron-withdrawing nature of the carboxyl groups activates the double bonds, allowing them to react with nucleophiles like amines thiols and enolates. This property enables the construction of more complex organic molecules with diverse functional groups, which are essential in the synthesis of pharmaceuticals, agrochemicals, and natural product analogs.This property allows the construction of complex organic molecules that have diverse functional groups. These are essential for the synthesis and agrochemicals of natural products, pharmaceuticals, and enolates.
Regarding its application in the pharmaceutical industry, derivatives of (2E)-3-ethoxyacrylic acid can potentially exhibit biological activities.Derivates of (2E-3)-3-ethoxyacrylic acids can potentially show biological activity in their application to the pharmaceutical industry. The structure can be modified to target specific biological pathways.The structure can also be modified to target specific biological pathways. Some analogs might have antibacterial or antifungal properties.Some analogs may have antibacterial or even antifungal properties. By incorporating this acid into a larger molecular framework, researchers can design molecules that interact with key enzymes or receptors in microorganisms, disrupting their normal functions and leading to growth inhibition or cell death.Researchers can use this acid to design molecules that interfere with the normal functions of microorganisms. This could lead to cell death or growth inhibition.
In the area of agrochemicals, (2E)-3-ethoxyacrylic acid can play a role in the development of pesticides.In the field of agrochemicals (2E)-3 ethoxyacrylic can play a key role in the development and production of pesticides. Similar to its use in pharmaceuticals, modified forms of this compound can be designed to target pests while being relatively safe for crops.Modified forms of this compound, similar to its use in the pharmaceutical industry, can be designed to target insects while being relatively safe to crops. It could act as an active ingredient in herbicides, insecticides, or fungicides.It could be used as an active ingredient in insecticides or fungicides. For example, in the case of fungicides, the molecule's structure can be optimized to interfere with the metabolic processes of fungal pathogens that attack plants, thus protecting the crops from diseases and improving agricultural yields.In the case of fungicides for example, the molecule structure can be optimized in order to interfere with the metabolism of fungal pathogens which attack plants. This will protect the crops from disease and improve agricultural yields.
Moreover, in materials science, (2E)-3-ethoxyacrylic acid can be used in the synthesis of specialty polymers.In materials science, the (2E)-3 -ethoxyacrylic acids can also be used to synthesize specialty polymers. The double bond can be polymerized, either alone or in combination with other monomers, to create polymers with unique properties.Double bonds can be polymerized alone or in combination other monomers to create polymers that have unique properties. These polymers might have enhanced mechanical strength, solubility, or thermal stability depending on the reaction conditions and the co - monomers used.These polymers may have improved mechanical strength, thermal stability, or solubility depending on the reaction conditions. They can find applications in coatings, adhesives, and advanced materials where specific physical and chemical properties are required.They can be used in coatings and adhesives as well as advanced materials that require specific chemical and physical properties.
What are the physical and chemical properties of (2E)-3-ethoxyacrylic acid?
(2E)-3-ethoxyacrylic acid is a compound with distinct physical and chemical properties.The (2E)-3 ethoxyacrylic is a compound that has distinct physical and chemistry properties.
Physical Properties
Appearance
Typically, (2E)-3-ethoxyacrylic acid exists as a colorless to pale - yellow liquid under standard conditions.Under standard conditions, (2E-3)-3-ethoxyacrylic acids are a colorless or pale-yellow liquid. This color is due to the nature of its molecular structure and the lack of highly conjugated chromophores that would otherwise impart a more intense color.This color is due in part to its molecular composition and the absence of highly conjugated colorants that would otherwise give it a more intense hue.
Boiling Point
The boiling point of (2E)-3-ethoxyacrylic acid is influenced by its intermolecular forces.Intermolecular forces influence the boiling point of (2E-3)-3-ethoxyacrylic acids. It has a boiling point that is relatively high, which can be attributed to the presence of hydrogen - bonding interactions between the carboxylic acid groups of different molecules, as well as van der Waals forces.It has a relatively high boiling point, which is attributed to hydrogen-bonding interactions between carboxylic acids of different molecules as well as van der waals forces. The specific boiling point value can be determined experimentally, but generally, it falls within a range characteristic of similar organic acids with alkoxy side - chains.The boiling point can be determined by experiment, but it generally falls within the range of values characteristic of organic acids with alkoxy-side - chains.
Melting Point
The melting point of this compound is also related to its intermolecular forces.The melting point is also influenced by the intermolecular force of this compound. Given the relatively small size of the molecule and the presence of polar functional groups, the melting point is likely to be low enough that it is a liquid at room temperature.The melting point of this compound is likely to be so low that it is liquid at room temperatures due to its small size and presence of polar functional group. The carboxylic acid group can form hydrogen bonds, which tend to increase the melting point compared to non - polar compounds of similar size, but the overall molecular structure and the presence of the ethoxy group also play a role in determining the exact melting point.The carboxylic group can form hydrogen bonding, which tends to increase the melting temperature compared to non-polar compounds of similar sizes. However, the overall molecular composition and the presence of ethoxy groups also play a part in determining the melting point.
Solubility
(2E)-3-ethoxyacrylic acid is soluble in polar organic solvents such as ethanol, methanol, and acetone.The polar organic solvents ethanol, methanol and acetone are soluble in (2E)-3 -ethoxyacrylic acids. This solubility is due to the ability of the carboxylic acid group to form hydrogen bonds with the solvent molecules, and the ethoxy group also contributes to its compatibility with organic solvents.This is due to the carboxylic group's ability to form hydrogen bonds with solvent molecules. The ethoxy group contributes to its compatibility. In water, its solubility is limited but still present to some extent because of the polar nature of the carboxylic acid group, which can interact with water molecules through hydrogen bonding.Its solubility in water is limited, but still present, due to the polarity of the carboxylic group, which can interact through hydrogen bonds with water molecules.
Chemical Properties
Acidity
The carboxylic acid group in (2E)-3-ethoxyacrylic acid is responsible for its acidic properties.The carboxylic group in (2E-3)-3-ethoxyacrylic is responsible for the acidic properties of this acid. It can donate a proton in the presence of a base, following the general acid - base reaction mechanism.It can donate a proton in the presence a base following the general acid-base reaction mechanism. The acidity is influenced by the electron - withdrawing or donating effects of the adjacent ethoxy group.The electron-donating or -withdrawing effects of the adjacent group ethoxy influence the acidity. The ethoxy group, with its inductive effect, can either stabilize or destabilize the conjugate base formed after proton donation.The ethoxy groups inductive effect can either stabilize or destroy the conjugate base after proton donation. In this case, the inductive effect of the ethoxy group may slightly decrease the acidity compared to acrylic acid itself due to its electron - donating nature, which would make the negative charge on the conjugate base less stable.The ethoxy group's inductive effect may reduce the acidity of acrylic acid by a small amount due to its electron-donating nature. This would make the conjugate base's negative charge less stable.
Reactivity of the Double BondDouble Bond Reactivity
The double bond in (2E)-3-ethoxyacrylic acid is reactive towards electrophilic addition reactions.The double bond in (2E-3)-3-ethoxyacrylic acids is reactive to electrophilic addition reactions. Common electrophiles such as bromine, hydrogen halides can react with the double bond.The double bond can be reacted with by common electrophiles, such as hydrogen halides and bromine. For example, in the presence of bromine, a bromination reaction occurs, where the double bond breaks and two bromine atoms add across the double bond.In the presence of bromine for example, the double bonds breaks and two bromine molecules are added across the double bonds. This reaction is characteristic of alkenes and is used in synthetic organic chemistry to introduce new functional groups or modify the structure of the molecule.This reaction is a characteristic of alkenes, and is used to introduce new functional groups into the molecule or modify its structure.
Esterification Reaction
The carboxylic acid group in (2E)-3-ethoxyacrylic acid can participate in esterification reactions.The carboxylic group in (2E-3)-3-ethoxyacrylic can participate in esterification. When reacted with an alcohol in the presence of an acid catalyst, it forms an ester.It forms an ester when it reacts with an alcohol, in the presence an acid catalyst. This reaction is an important synthetic route for the preparation of various esters, which have applications in flavors, fragrances, and as solvents.This reaction is a key synthetic route to produce various esters that are used in flavorings, fragrances, or as solvents. The ethoxy group on the molecule can also influence the reaction rate and the properties of the resulting ester.The ethoxy groups on the molecule may also affect the reaction rate and properties of the ester.
How is (2E)-3-ethoxyacrylic acid synthesized?
(2E)-3 - ethoxyacrylic acid can be synthesized through the following general approach.The following general method can be used to synthesize (2E)-3-ethoxyacrylic acids.
1. Preparation of starting materialsPrepare the starting materials
Typically, ethyl acetoacetate is a common starting compound.Ethyl Acetoacetate is usually a common starting material. Ethyl acetoacetate can be easily obtained commercially.Ethyl Acetoacetate is easily available commercially. It contains a carbonyl group and an ester group, which are crucial for subsequent reactions.It contains a ester and a carbonyl groups, which are essential for subsequent reactions.
2. Alkylation stepAlkylation step
Ethyl acetoacetate is treated with an appropriate alkylating agent to introduce the ethoxy group.Ethylacetoacetate undergoes a treatment with an alkylating agent that introduces the ethoxy groups. For example, reacting ethyl acetoacetate with ethyl bromide in the presence of a base such as sodium ethoxide.Reacting ethylacetoacetate in the presence a base, such as sodium ethoxide, with ethylbromide. The base deprotonates the relatively acidic a - hydrogen of ethyl acetoacetate, forming an enolate ion.The base deprotonates a -hydrogen of ethylacetoacetate which is relatively acidic, forming an Enolate ion. This enolate ion then attacks the ethyl bromide via an SN2 mechanism.This enolate ion attacks the ethylbromide through an SN2 reaction. The reaction can be carried out in an inert solvent like ethanol.The reaction can take place in an inert ethanol. The product of this reaction is an alkylated ethyl acetoacetate derivative with an ethoxy group at the a - position.This reaction produces an alkylated derivative of ethylacetoacetate with an ethoxy at the a-position.
3. Hydrolysis and decarboxylationHydrolysis and decarboxylation
The alkylated ethyl acetoacetate is then subjected to hydrolysis.Hydrolysis is performed on the alkylated ethylacetoacetate. This can be achieved by refluxing the compound with an aqueous solution of a strong base, such as sodium hydroxide.This can be done by refluxing the compound in an aqueous base solution, such as sodium chloride. During hydrolysis, the ester group is cleaved, forming the corresponding carboxylate salt.During hydrolysis the ester group is cleaved to form the carboxylate salt. After hydrolysis, acidification with a strong acid like hydrochloric acid is carried out to convert the carboxylate salt into the carboxylic acid.After hydrolysis is completed, the carboxylate salt is converted into carboxylic acid by acidification using a strong acid such as hydrochloric.
Subsequently, decarboxylation occurs when the resulting b - keto acid is heated.Decarboxylation then occurs when the b-keto acid is heated. The b - keto acid structure is prone to decarboxylation due to the presence of the adjacent carbonyl groups.Decarboxylation is possible due to the presence adjacent carbonyl groups in the b - keto acid structure. During decarboxylation, carbon dioxide is lost, and the (2E)-3 - ethoxyacrylic acid is formed.During decarboxylation carbon dioxide is lost and (2E)-3-ethoxyacrylic acids are formed. The double bond in the product is in the E - configuration, which is often favored due to the stability of the trans - like arrangement of substituents around the double bond.The double bond is in an E-configuration, which is favored because of the stability of the trans-like arrangement of substituents surrounding the double bond. This synthesis route provides a practical way to access (2E)-3 - ethoxyacrylic acid in a multi - step process, with each step carefully controlled to ensure high yields and purity of the final product.This multi-step synthesis provides a practical method to obtain (2E)-3-ethoxyacrylic acids. Each step is carefully controlled to ensure high yields, and purity of the end product.
What are the safety precautions when handling (2E)-3-ethoxyacrylic acid?
(2E)-3-ethoxyacrylic acid is a chemical compound, and when handling it, several safety precautions should be taken.When handling (2E)-3 - ethoxyacrylic acids, it is important to take several safety precautions.
First, personal protective equipment (PPE) is essential.Personal protective equipment (PPE), first and foremost, is essential. Wear appropriate chemical - resistant gloves.Wear gloves that are resistant to chemicals. Nitrile gloves are often a good choice as they can resist many chemicals.Nitrile gloves can be a good option as they are resistant to many chemicals. This protects the hands from potential contact with the acid, which could cause skin irritation, burns, or absorption through the skin.This will protect your hands from any acid that could cause irritation, burns or absorption. Also, put on safety goggles or a face shield.Wear safety goggles or face shields. This shields the eyes from any splashes of the acid.This will protect your eyes from any acid splashes. Eye contact with (2E)-3-ethoxyacrylic acid can lead to severe eye damage, including corneal burns and vision impairment.Eye contact with (2E-3)-3-ethoxyacrylic can cause severe eye damage including corneal burning and vision impairment.
Second, work in a well - ventilated area.Second, make sure you are working in an area that is well-ventilated. A fume hood is highly recommended if available.If you have the option, a fume hood would be highly recommended. (2E)-3-ethoxyacrylic acid may give off vapors that can be irritating to the respiratory system.The vapors of (2E)-3 ethoxyacrylic acids can be irritating to respiratory systems. Inhalation of these vapors can cause coughing, shortness of breath, and potentially more serious lung problems.Inhaling these vapors may cause coughing, shortness or breath, and even more serious lung problems. Good ventilation helps to dilute and remove these vapors from the work area.This vapor can be removed from the area by using good ventilation.
Third, when storing (2E)-3-ethoxyacrylic acid, keep it in a cool, dry place away from sources of heat and ignition.Third, store (2E)-3 ethoxyacrylic in a cool and dry place, away from heat sources and ignition. It is important to store it in a properly labeled container to prevent misidentification.To prevent misidentification, it is important to store the acid in a container that is clearly labeled. Additionally, store it separately from incompatible substances.Store it separately from other substances. Acids can react violently with bases, reducing agents, and some metals, so make sure to avoid such combinations.Avoid storing acids with bases, reducing substances, and certain metals.
Fourth, in case of skin contact, immediately rinse the affected area with plenty of water for at least 15 minutes.In the event of skin contact, rinse the affected area immediately with plenty of water and for at least 15 min. Remove any contaminated clothing during this process.During this process, remove any contaminated clothing. After rinsing, seek medical attention if there are any signs of irritation or burns.If you notice any signs of irritation, or burns, seek medical help. If the acid gets into the eyes, rinse the eyes thoroughly with clean water for at least 15 minutes, holding the eyelids open.If the acid has gotten into your eyes, rinse them thoroughly with clean, running water for 15 minutes while keeping the eyelids wide open. Then, seek immediate medical help.Seek immediate medical attention.
Finally, when disposing of (2E)-3-ethoxyacrylic acid or any waste containing it, follow local environmental regulations.Follow local environmental regulations when disposing of (2E-3)-3-ethoxyacrylic acids or any waste that contains it. Do not pour it down the drain or discard it in regular trash.Do not dispose of it in the regular trash or down the drain. Contact the appropriate waste management facilities to ensure proper and safe disposal to prevent environmental contamination.Contact the appropriate waste management facility to ensure proper and secure disposal to prevent contamination of the environment.
What are the storage conditions for (2E)-3-ethoxyacrylic acid?
(2E)-3-ethoxyacrylic acid should be stored under specific conditions to maintain its stability and quality.To maintain its quality and stability, it is important to store (2E)-3 -ethoxyacrylic Acid under certain conditions.
First, it is crucial to store it in a cool environment.It is important to store the compound in a cool place. High temperatures can accelerate chemical reactions, potentially leading to decomposition or polymerization of the compound.High temperatures can speed up chemical reactions and lead to the decomposition or polymerization. A storage temperature in the range of 2 - 8 degrees Celsius is often ideal.Ideal storage temperatures are usually between 2 and 8 degrees Celsius. This temperature range helps to slow down any thermal - induced degradation processes.This temperature range can help to slow down thermal-induced degradation processes.
Secondly, the storage area should be dry.Second, the storage area must be dry. Moisture can react with (2E)-3-ethoxyacrylic acid.Moisture may react with (2E-3)-3-ethoxyacrylic acids. For instance, water might hydrolyze the ester - like structure in the molecule if present in the compound.Water, for example, could hydrolyze an ester-like structure in the molecule. This can change its chemical properties and reduce its purity.This can alter its chemical properties, and reduce its purity. Therefore, keeping it away from sources of humidity, such as in a desiccator or a well - sealed container in a dry room, is necessary.It is important to keep it away from sources such as humidity. For example, in a desiccator, or in a well-sealed container in a room that is dry.
Thirdly, light should be avoided.Thirdly, avoid light. (2E)-3-ethoxyacrylic acid may be sensitive to light, especially ultraviolet light.Light, and especially ultraviolet light, may make (2E)-3 -ethoxyacrylic acids sensitive. Photochemical reactions can occur when exposed to light, which can break chemical bonds in the molecule and cause unwanted transformations.When exposed to light, photochemical reactions can occur. This can cause unwanted transformations and break chemical bonds. Storing it in opaque containers or in a dark place helps to prevent such light - induced reactions.Storing it in dark or opaque containers can help prevent light-induced reactions.
Fourthly, proper containment is essential.In the fourth place, it is important to ensure that the compound is contained properly. The compound should be stored in a well - sealed container.The compound must be stored in an airtight container. This not only prevents moisture and air from entering but also stops the release of the chemical into the surrounding environment.This will not only stop moisture and air from entering, but also prevent the release of chemicals into the environment. A tightly closed glass or plastic container with a good - quality seal is recommended.It is best to use a tightly sealed glass or plastic container. If the container is not properly sealed, evaporation of the volatile components of the acid may occur, and oxidation by air can also take place.If the container isn't properly sealed, the volatile components in the acid can evaporate and the container may also oxidize.
Finally, it is important to store (2E)-3-ethoxyacrylic acid away from incompatible substances.Store (2E)-3 ethoxyacrylic acids away from incompatible substances. Substances such as strong acids, strong bases, and oxidizing agents can react with it.It can react with substances such as strong bases, strong acids, and oxidizing agent. For example, strong bases can deprotonate the carboxylic acid group, while oxidizing agents can oxidize the double bond or other parts of the molecule.Strong bases, for example, can deprotonate carboxylic acid groups, while oxidizing agent can oxidize double bonds or other parts of a molecule. Keeping it separated from such reactive chemicals in a dedicated storage area helps to ensure its long - term stability.Separating it from other reactive chemicals and storing it in a separate area will help to ensure its long-term stability.