(e)-2-cyano-3-(1-phenyl-1h-indol-3-yl)acrylic Acid


Properties

product_name (E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid
CAS_number 54963-44-1
formula C18H12N2O2
molar_mass 288.3
property_1 yellow solid
property_2 soluble in organic solvents
property_3 melting point approx. 160-162°C
property_4 pKa around 4-5
property_5 UV maximum absorption at ~383 nm
property_6 crystalline appearance
property_7 used in organic synthesis
property_8 stable under standard conditions
property_9 hazards: may cause irritation
property_10 logP (octanol-water) 2.5-3

FAQ

What is (E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid?

(E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid, also known as Indirubin-3'-Monoxime, is a synthetic compound derived from indole and acrylic acid. It is commonly used in research settings for its potential therapeutic properties, particularly in cancer research.

What are the potential therapeutic benefits of (E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid?

Studies have shown that (E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid exhibits anti-inflammatory, anti-cancer, and anti-microbial properties. It has been investigated for its potential role in inhibiting cell proliferation, inducing apoptosis, and reducing inflammation in various disease models.

How is (E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid typically used in research?

Researchers often utilize (E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid in in vitro and in vivo studies to investigate its effects on various cellular pathways and biological processes. It can be administered to cells or animals through different experimental protocols to assess its pharmacological activities.

What are some of the key findings regarding the mechanism of action of (E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid?

One of the main mechanisms of action of (E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid is its ability to inhibit specific signaling pathways involved in cell proliferation and survival. It has been shown to target key molecules in cancer cells, leading to their growth inhibition and apoptosis induction.

Are there any potential side effects or toxicities associated with (E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid?

While (E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid has shown promising therapeutic properties in various studies, it is essential to consider potential side effects and toxicities. Researchers should carefully evaluate its safety profile and dose-dependent effects in preclinical and clinical studies.

What are some current research trends involving (E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid?

Recent research efforts have focused on exploring the molecular mechanisms underlying the anti-cancer effects of (E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid, as well as its potential applications in other disease models. Scientists are also investigating novel drug delivery systems to enhance its therapeutic efficacy.

In what ways can (E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid contribute to the field of pharmacology and drug discovery?

(E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid represents a valuable tool for pharmacologists and drug discovery researchers due to its diverse pharmacological properties. By studying its effects on cellular pathways, scientists can identify new drug targets and develop innovative therapeutic strategies.

How can researchers obtain high-quality (E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid for their experiments?

Researchers can acquire (E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid from reputable chemical suppliers that offer reliable and pure compounds for research purposes. It is essential to ensure the compound's quality and stability before using it in experiments to obtain accurate and reproducible results.

What future prospects do you see for the continued study and application of (E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid in biomedical research?

The ongoing research on (E)-2-cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid is likely to uncover new therapeutic avenues and potential clinical applications in the field of biomedicine. By further elucidating its mechanisms of action and optimizing its pharmacological properties, scientists can harness its full potential for treating various diseases.