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Product Name | 1,2-Dihydroxy-1,2-cyclobutanediacrylic Acid Di-g-lactone |
Cas Number | 89-11-4 |
Formula | C8H8O4 |
Molar Mass | 168.15 g/mol |
Melting Point | 132-134°C |
Boiling Point | 318-320°C |
Density | 1.5 g/cm3 |
Solubility | Soluble in water |
Appearance | Yellow crystalline solid |
Odor | Odorless |
Flash Point | 146°C |
Ph | 3.2-4.0 |
What are the main applications of 1,2-Dihydroxy-1,2-cyclobutanediacrylic Acid Di-g-lactone?
1,2 - Dihydroxy - 1,2 - cyclobutanediacrylic Acid Di - g - lactone, also known as squaric acid diglycolyl lactone, has several important applications.The 1,2 – Dihydroxy – 1,2 – cyclobutanediacrylic acid Di -g - Lactone, also known by the name squaric Acid Diglycolyl Lactone, has many important applications.
In the field of materials science, it can be used as a monomer for the synthesis of novel polymers.In materials science, this compound can be used to synthesize novel polymers. The unique structure of this compound imparts special properties to the resulting polymers.The unique structure of the compound confers special properties to polymers. For example, the cyclic and lactone - containing structure can potentially contribute to the formation of polymers with good thermal stability.The cyclic and lactone-containing structure, for example, can potentially contribute to polymers with high thermal stability. These polymers may find use in high - temperature - resistant coatings or components in the aerospace or automotive industries, where materials need to withstand extreme heat conditions without significant degradation.These polymers can be used in coatings and components for aerospace or automotive industries that require materials to withstand extreme temperatures without degradation.
In the realm of organic synthesis, it serves as a valuable building block.It is a very useful building block in organic synthesis. Its reactive functional groups allow for the creation of a wide variety of complex organic molecules.Its reactive functional group allows for the creation a wide range of complex organic molecules. Chemists can utilize it to construct molecules with specific stereochemistry and functionality.It can be used by chemists to create molecules with specific stereochemistry or functionality. It can participate in reactions such as cycloadditions, where it can be incorporated into larger ring - containing structures.It can be used in cycloadditions and other reactions where it can be incorporated to larger ring-containing structures. These synthetic molecules may have applications in the production of fine chemicals, pharmaceuticals, and agrochemicals.These synthetic molecules can be used to produce fine chemicals, pharmaceuticals and agrochemicals.
Regarding pharmaceuticals, derivatives of 1,2 - Dihydroxy - 1,2 - cyclobutanediacrylic Acid Di - g - lactone may possess biological activities.In terms of pharmaceuticals, the derivatives of Dihydroxy 1,2 cyclobutanediacrylic acid Di -g -lactone may possess biological activity. Some studies have explored its potential as an antibacterial or antifungal agent.Some studies have investigated its potential as an agent that is antibacterial or antifungal. The specific structure might interact with key biological targets in microorganisms, disrupting their normal metabolic processes.The specific structure could interact with key targets in microorganisms and disrupt their normal metabolic processes. Additionally, it could potentially be used as a scaffold for the design of new drugs.It could also be used to design new drugs. By modifying the substituents around the core structure, chemists can fine - tune the drug's properties, such as its solubility, bioavailability, and target selectivity.By changing the substituents in the core structure of the drug, chemists are able to fine-tune its properties, including its solubility and bioavailability.
In the area of surface - active agents, certain compounds derived from it can exhibit surfactant - like properties.Certain compounds derived from it may exhibit properties similar to surfactants in the area of surface-active agents. They can reduce the surface tension at the interface between two phases, such as liquid - liquid or liquid - solid interfaces.They can reduce surface tension between two phases such as liquid-liquid or liquid-solid interfaces. This property makes them useful in applications like emulsification, where they can help in the formation and stabilization of emulsions.This property makes them useful for applications such as emulsification where they can assist in the stabilization and formation of emulsions. For instance, in the formulation of cosmetics or food products, these surfactant - like derivatives can ensure the homogeneous mixing of immiscible components.These derivatives, which are similar to surfactants, can be used in the formulation of food or cosmetic products to ensure homogeneous mixing.
Overall, 1,2 - Dihydroxy - 1,2 - cyclobutanediacrylic Acid Di - g - lactone has diverse applications across multiple scientific and industrial fields, with potential for further exploration and development in the future.Overall, 1,2 Dihydroxy -1,2 cyclobutanediacrylic acid Di -g - Lactone has diverse applications in multiple scientific and industrial areas, with potential for future exploration and development.
What are the key properties of 1,2-Dihydroxy-1,2-cyclobutanediacrylic Acid Di-g-lactone?
1,2 - Dihydroxy - 1,2 - cyclobutanediacrylic Acid Di - g - lactone likely has several key properties.Di -g - Lactone Di - 2 - Dihydroxy 1,2 – cyclobutanediacrylic acid likely has several key characteristics.
In terms of physical properties, its state at room temperature would depend on factors such as its molecular structure and intermolecular forces.Its state at room temperatures would depend on factors like its molecular structures and intermolecular force. It might be a solid due to the presence of lactone rings which can contribute to a relatively ordered molecular packing.It could be a solid because of the lactone rings, which can contribute towards a relatively orderly molecular packing. The presence of the di - hydroxy and lactone functional groups can also influence its melting and boiling points.The presence of di-hydroxyl and lactone functional group can also affect its melting and boiling point. The hydrogen - bonding capabilities of the hydroxyl groups can increase the intermolecular forces, leading to a relatively high melting point compared to non - polar or less hydrogen - bonding - capable compounds.The hydrogen-bonding abilities of the hydroxyl group can increase the intermolecular force, leading to a relatively higher melting point when compared to non-polar or less hydrogen-bonding-capable compounds.
Regarding solubility, the hydrophilic nature of the hydroxyl groups would suggest some solubility in polar solvents such as water, alcohols, and possibly polar aprotic solvents like dimethyl sulfoxide (DMSO).In terms of solubility, it is likely that the hydroxyl groups are soluble in polar solvents, such as alcohols, water, and perhaps polar aprotic solutions like dimethyl sulfoxide. However, the presence of the relatively non - polar cyclobutane ring and the lactone structures might limit its solubility in highly polar solvents to some extent.The lactone structure and the non-polar cyclobutane rings may limit its solubility to some extent in highly polar solvents. The balance between the hydrophilic and hydrophobic parts of the molecule would determine its solubility profile.The balance between hydrophilic and non-hydrophilic parts of the molecule will determine its solubility.
From a chemical reactivity perspective, the hydroxyl groups are reactive.The hydroxyl groups have a high reactivity. They can participate in esterification reactions, either with other carboxylic acids or with compounds containing suitable electrophilic centers.They can participate in esterifications, either with other carboxylic acid or with compounds that contain suitable electrophilic centres. The lactone rings are also reactive.The lactone rings can also be reactive. They can be hydrolyzed under acidic or basic conditions.They can be hydrolyzed in acidic or basic conditions. In basic media, the lactone ring would likely open to form the corresponding carboxylate and alcohol moieties, a reaction known as lactone hydrolysis.In basic media, it is likely that the lactone ring will open and form the carboxylates and alcohol moieties. This reaction is known as lactonehydrolysis. This hydrolysis can be reversible under certain conditions.This hydrolysis is reversible in certain conditions.
The double - bond in the acrylic acid part of the structure imparts additional reactivity.The double-bond in the acrylic acid portion of the structure confers additional reactivity. It can undergo addition reactions, such as electrophilic addition with reagents like bromine or hydrogen halides.It can undergo addition reaction, such as electrophilic with reagents such as bromine or hydrogen chlorides. It can also participate in polymerization reactions, especially if conditions are suitable for radical or ionic polymerization mechanisms.It can also be used in polymerization reactions if the conditions are right for radical or ionic mechanisms. This could potentially be used to form polymers with interesting properties, perhaps incorporating the unique cyclobutane and lactone - containing units into the polymer backbone.This could be used to create polymers with interesting properties by incorporating the unique cyclobutane- and lactone-containing units into polymer backbones.
The compound may also have potential biological properties.The compound may also possess biological properties. The presence of the various functional groups can interact with biological molecules.The presence of functional groups can interact biological molecules. For example, the hydroxyl groups can potentially form hydrogen bonds with proteins or nucleic acids, which could lead to biological activity such as enzyme inhibition or binding to DNA.For example, hydroxyl groups could potentially form hydrogen bond with proteins or nucleic acid, which would lead to biological activity, such as enzyme inhibition, or binding to DNA. However, detailed knowledge of its biological activity would require further in - vitro and in - vivo studies.Further in-vitro and in-vivo studies are needed to determine its biological activity.
How is 1,2-Dihydroxy-1,2-cyclobutanediacrylic Acid Di-g-lactone synthesized?
1,2 - Dihydroxy - 1,2 - cyclobutanediacrylic Acid Di - g - lactone can potentially be synthesized through the following general approach.The following general approach can be used to synthesize 1,2 – Dihydroxy – 1,2 – cyclobutanediacrylic acid Di – g – lactone.
1. Starting materials selectionSelecting the right materials to start with
Typically, compounds with suitable functional groups that can be manipulated to form the cyclobutane ring and the lactone moieties are chosen.Compounds with functional groups that are suitable for forming the cyclobutane rings and lactone moieties can be chosen. For example, compounds containing double bonds and hydroxyl - or carboxyl - like groups can serve as starting points.As a starting point, compounds with double bonds or hydroxyl- or carboxyl-like groups are ideal. A common strategy might involve using acrylic - acid - related derivatives.One common strategy is to use derivatives of acrylic acid. These starting materials are relatively accessible in the chemical market or can be synthesized through standard organic chemistry procedures.These materials can be found on the chemical market, or synthesized using standard organic chemistry methods.
2. Cyclization to form the cyclobutane ring2.
One possible method for cyclization is through a [2 + 2] cycloaddition reaction.A [2 + 2] reaction is one way to cyclize. If starting with appropriate unsaturated compounds, under specific reaction conditions such as irradiation with ultraviolet light or in the presence of certain catalysts, two double - bond - containing molecules can react to form a cyclobutane ring.Under certain conditions, such as ultraviolet light or the presence of catalysts, two molecules containing double bonds can react under certain conditions to form a cyclobutane. For instance, if we have two acrylic - type molecules with proper substitution patterns, they can be made to undergo a [2 + 2] cycloaddition.If we have two acrylic-type molecules with the right substitution patterns, then they can undergo a [2+2] cycloaddition. This reaction is regioselective and stereoselective to some extent, depending on the reaction conditions and the nature of the substituents on the starting unsaturated compounds.This reaction can be regioselective or stereoselective depending on the conditions of the reaction and the natures of the substituents in the starting compounds.
3. Formation of the lactone groupsFormation of lactone groups
After the formation of the cyclobutane ring, the introduction of the lactone groups can be achieved.After the formation of a cyclobutane, it is possible to introduce lactone groups. If the cyclobutane - containing intermediate has carboxylic acid and hydroxyl groups in the appropriate positions, an intramolecular esterification reaction can occur.The intramolecular esterification can occur if the cyclobutane-containing intermediate contains carboxylic acid groups and hydroxyls in the correct positions. This can be promoted by using dehydrating agents such as concentrated sulfuric acid or by heating the reaction mixture under reflux in the presence of an acid catalyst like p - toluenesulfonic acid.This can be accelerated by dehydrating agents like concentrated sulfuric acid, or by heating the mixture under reflux with an acid catalyst such as p-toluenesulfonic acids. The hydroxyl group and the carboxylic acid group will react to form the lactone ring.The reaction between the hydroxyl and carboxylic acid groups will form the lactone ring. The reaction conditions need to be carefully controlled to ensure the formation of the desired di - g - lactone product.To ensure the desired di-g-lactone product, the reaction conditions must be carefully controlled. For example, the reaction temperature should be optimized to avoid side reactions such as over - dehydration or rearrangement of the cyclobutane ring.For example, the temperature of the reaction should be optimized in order to avoid side reactions like over-dehydration or rearrangement the cyclobutane rings.
4. Purification and isolationPurification and isolation
Once the synthesis is complete, the crude product is usually a mixture of the desired 1,2 - Dihydroxy - 1,2 - cyclobutanediacrylic Acid Di - g - lactone and various by - products.After the synthesis, the crude product is a mixture consisting of the desired 1,2 Dihydroxy -1,2 cyclobutanediacrylic acid Di -g – lactone and other by-products. Purification methods such as column chromatography can be used.You can use purification methods like column chromatography. The crude product is loaded onto a column packed with an appropriate stationary phase, like silica gel.The crude product is loaded on a column filled with a suitable stationary phase, such as silica gel. A suitable eluent, a mixture of solvents such as hexane and ethyl acetate in different ratios, is then passed through the column.The column is then passed with an eluent mixture, such as hexane/ethyl-acetate in various ratios. The different compounds in the mixture will elute at different rates based on their polarity and interaction with the stationary phase, allowing for the isolation of the pure 1,2 - Dihydroxy - 1,2 - cyclobutanediacrylic Acid Di - g - lactone.The polarity of the compounds and their interaction with the stationary phase will determine the rate at which they elute. This allows for the separation of pure 1,2 Dihydroxy -1,2 cyclobutanediacrylic acid Di -g - lactone. Recrystallization can also be employed to further purify the product, by dissolving the isolated compound in a suitable solvent and then slowly cooling the solution to precipitate out pure crystals of the target molecule.Recrystallization is another method to purify the product. This involves dissolving the isolated compound into a suitable solvent, and then cooling the solution slowly to precipitate pure crystals.
What are the safety precautions when handling 1,2-Dihydroxy-1,2-cyclobutanediacrylic Acid Di-g-lactone?
1,2 - Dihydroxy - 1,2 - cyclobutanediacrylic Acid Di - g - lactone is likely a relatively specialized and potentially hazardous chemical.Di -g - Lactone Di - 2 - Dihydroxy-1,2 cyclobutanediacrylic acid is a potentially hazardous and highly specialized chemical. Here are some general safety precautions when handling it.Here are some safety precautions to take when handling this chemical.
Firstly, personal protective equipment is essential.Personal protective equipment is a must. Wear appropriate chemical - resistant gloves.Wear gloves that are resistant to chemicals. Nitrile gloves are often a good choice as they can resist a wide range of chemicals.Nitrile gloves can be a good option as they are resistant to a variety of chemicals. This helps prevent skin contact, which could lead to irritation, absorption, or allergic reactions.This will help prevent skin contact that could cause irritation, absorption or allergic reactions. Also, put on safety goggles or a face shield.Wear safety goggles, or a face shield. This safeguards the eyes from any splashes or fumes that might be released during handling.This protects the eyes against any fumes or splashes that may be released when handling. In addition, wear a lab coat or a chemical - resistant apron to protect clothing and skin on the body from potential spills.Wear a lab coat, or a chemical-resistant apron, to protect clothing from spills.
Secondly, work in a well - ventilated area.Second, make sure that you are working in an area with good ventilation. A fume hood is highly recommended.A fume hood should be used. This device effectively removes any fumes, vapors, or dusts generated during the handling process, reducing the risk of inhalation.This device removes all fumes, dusts, and vapors that are generated during the handling procedure, reducing the chance of inhalation. Inhalation of chemicals can cause respiratory problems, ranging from mild irritation to more serious long - term damage.Inhaling chemicals can cause respiratory issues, from mild irritation to long-term damage.
Thirdly, when transferring or measuring the chemical, use proper equipment.Thirdly, make sure you use the right equipment when transferring or weighing the chemical. Use calibrated pipettes, burettes, or measuring cylinders to ensure accurate amounts are used and to minimize the chance of spills.To ensure that the correct amount is used, and to reduce spills, use calibrated pipettes or measuring cylinders. When pouring, do it slowly and carefully to avoid splashing.Pour slowly and carefully to prevent splashing.
Fourthly, be aware of storage requirements.Be aware of the storage requirements. Store 1,2 - Dihydroxy - 1,2 - cyclobutanediacrylic Acid Di - g - lactone in a cool, dry place away from heat sources, ignition sources, and incompatible substances.Store 1,2 Dihydroxy -1,2 Cyclobutanediacrylic acid Di - G - Lactone in a dry, cool place away from heat, ignition sources and incompatible substances. Keep it in a properly labeled container to prevent confusion.Keep it in a container that is clearly labeled to avoid confusion.
Fifthly, in case of accidental exposure, know the appropriate first - aid measures.Fifthly, know what to do in the event of an accidental exposure. If it gets on the skin, immediately rinse the affected area with plenty of water for at least 15 minutes and then seek medical advice.If it gets onto the skin, rinse the area immediately with plenty of water and seek medical advice. If it splashes into the eyes, flush the eyes with copious amounts of water for at least 15 minutes and get prompt medical attention.If it splashes in the eyes, rinse the eyes for at least 15 min with lots of water and seek immediate medical attention. If inhaled, move to fresh air immediately and if breathing difficulties persist, call for emergency medical help.If inhaled, get to fresh air as soon as possible. If breathing problems persist, seek emergency medical attention.
Finally, ensure that all personnel handling this chemical are properly trained.Lastly, ensure that the personnel handling this chemical is properly trained. They should be familiar with its properties, potential hazards, and the correct safety procedures to follow.They should know its properties, any potential hazards and the correct safety procedures. Regular safety audits and refresher training can also help maintain a safe working environment.Regular safety audits can also help maintain an environment that is safe.
What are the potential risks associated with 1,2-Dihydroxy-1,2-cyclobutanediacrylic Acid Di-g-lactone?
1,2 - Dihydroxy - 1,2 - cyclobutanediacrylic Acid Di - g - lactone is likely a relatively specialized or less - commonly known chemical compound.1,2 – Dihydroxy – 1,2 – cyclobutanediacrylic acid Di – g - Lactone is likely to be a relatively specialized chemical compound or one that is less - well known. However, we can infer potential risks based on general chemical principles and knowledge of related compounds.We can, however, infer the potential risks from general chemical principles and our knowledge of related compounds.
One major area of concern is toxicity.Toxicology is a major concern. If this compound is absorbed into the body, it could potentially interfere with normal physiological processes.If this compound is absorbed by the body, it may interfere with normal physiological functions. For example, it might interact with enzymes in the body.It could, for example, interact with enzymes within the body. Enzymes are crucial for various metabolic reactions, and if the compound binds to an enzyme's active site or allosteric site, it could inhibit or modify the enzyme's function.Enzymes play a crucial role in metabolic reactions. If the compound binds with an enzyme's allosteric or active site, it can inhibit or modify its function. This could disrupt processes like energy production, cell repair, or the synthesis of important molecules such as proteins and nucleic acids, leading to adverse health effects.This could lead to adverse health effects by disrupting processes such as energy production, cell repairs, or the synthesis important molecules like proteins and nucleic acid.
Another risk could be related to its potential mutagenicity.Mutagenicity is another risk. Some cyclic and lactone - containing compounds have been shown to be mutagenic, meaning they can cause changes in DNA structure.Mutagenicity has been demonstrated for some cyclic and lactone-containing compounds, which can alter DNA structure. Mutations in DNA can lead to abnormal cell growth, potentially resulting in cancer.Mutations in DNA may lead to abnormal cell proliferation, which could result in cancer. If 1,2 - Dihydroxy - 1,2 - cyclobutanediacrylic Acid Di - g - lactone has the ability to insert itself into the DNA double helix or react with DNA bases, it could initiate these mutagenic events.If 1,2 Dihydroxy -1,2 cyclobutanediacrylic acid Di - G - Lactone has the ability insert itself into DNA double helixes or react with DNA base, it could trigger these mutagenic processes.
In an environmental context, if the compound is released into water bodies, soil, or the air, it may pose risks to ecosystems.If the compound is released in the environment, such as into soil, water, or air, it could pose a risk to ecosystems. Aquatic organisms could be particularly vulnerable.Aquatic organisms may be especially vulnerable. It might affect the survival, growth, and reproduction of fish, invertebrates, and other aquatic life.It could affect the growth, reproduction, and survival of fish, invertebrates and other aquatic organisms. In soil, it could interact with soil microorganisms, which play a vital role in nutrient cycling and soil fertility.In soil, it may interact with soil microorganisms that play a crucial role in soil fertility and nutrient cycling. Altering the activity of these microorganisms could have cascading effects on plant growth and the overall health of the terrestrial ecosystem.The activity of these microorganisms can have cascading impacts on plant growth and overall ecosystem health.
If the compound is volatile, there is also a risk of inhalation exposure.Inhalation exposure is possible if the compound is volatile. Inhaled particles or vapors can reach the lungs and then enter the bloodstream, potentially causing systemic effects throughout the body.Inhaled particles and vapors may reach the lungs, enter the bloodstream and cause systemic effects. Additionally, skin contact should not be overlooked.Skin contact is also important. Some chemicals can penetrate the skin and cause local irritation, allergic reactions, or be absorbed into the body, leading to internal health issues as well.Some chemicals can penetrate skin and cause irritation, allergic reactions or be absorbed by the body. This can lead to internal health problems. Overall, while specific data on this compound may be limited, these potential risks highlight the need for careful handling and study if it is used in industrial, research, or any other settings.While the specific data on this chemical may be limited, its potential risks are a reminder that it should be handled with care and studied if used in industrial or research settings.