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1-naphthylacrylic Acid


Properties
Product Name 1-Naphthylacrylic acid
Cas Number 2423-78-9
Formula C13H10O2
Molar Mass 198.22 g/mol
Melting Point 189-191 °C
Boiling Point 405 °C
Density 1.22 g/cm³
Solubility Slightly soluble in water
Appearance Off-white solid
Pka 4.34
Logp 3.3
Flash Point 203 °C
Refractive Index 1.645
Storage Temperature Store at room temperature
Hazards Irritant
FAQ

What is the application of 1-Naphthylacrylic acid?

1 - Naphthylacrylic acid is a compound with several notable applications.1 - Naphthylacrylic Acid is a compound that has many notable applications.
In the field of organic synthesis, it serves as a valuable building block.It is a useful building block in organic synthesis. Its structure, containing the naphthalene moiety and the acrylic acid functional group, allows chemists to create more complex organic molecules.Its structure, which contains the naphthalene molecule and the acrylic acid functional groups, allows chemists create more complex organic molles. For example, through reactions like esterification, the carboxylic acid group of 1 - naphthylacrylic acid can be modified to form esters.Through esterification, for example, the carboxylic group of 1 – naphthylacrylic can be modified into esters. These esters may have different physical and chemical properties, making them useful in various formulations.These esters can have different chemical and physical properties, making them useful for various formulations. Additionally, the double bond in the acrylic acid part can participate in polymerization reactions.The double bond of the acrylic acid can also participate in polymerization. By polymerizing 1 - naphthylacrylic acid or copolymerizing it with other monomers, materials with unique properties can be obtained.Materials with unique properties can also be produced by copolymerizing or polymerizing the 1 - naphthylacrylic acids with other monomers. These polymers may find applications in coatings, where their chemical resistance and film - forming properties can be exploited.These polymers can be used in coatings where their chemical resistance and films - forming abilities can be exploited.

In the area of materials science, 1 - naphthylacrylic acid can contribute to the development of functional materials.In the field of materials science, 1-naphthalylacrylic can contribute to the creation of functional materials. Due to the presence of the naphthalene ring, which has strong p - p stacking interactions, it can be used to design self - assembling materials.It can be used for self-assembling materials due to the strong interactions between the p-p stacking and the naphthalene rings. These self - assembled structures can have applications in areas such as drug delivery systems.These self-assembled structures have many applications, including drug delivery systems. The carboxylic acid group can be further modified to incorporate targeting moieties or to control the release of drugs.The carboxylic group can be modified to include targeting moieties, or to control drug release. Moreover, in the preparation of optical materials, the chromophoric nature of the naphthalene group in 1 - naphthylacrylic acid can endow the resulting materials with interesting optical properties.The chromophoric properties of the naphthalene groups in 1 -naphthylacrylic acids can be used to give optical materials interesting optical properties. For instance, they may exhibit fluorescence, which can be utilized in sensors or imaging applications.They may, for example, exhibit fluorescence that can be used in sensors or imaging.

In the realm of biological research, 1 - naphthylacrylic acid derivatives have shown potential bioactivity.In biological research, the 1 - naphthylacrylic acids derivatives have shown bioactivity. Some derivatives may have antibacterial or antifungal properties.Some derivatives could have antibacterial and antifungal properties. The unique structure of the compound can interact with the cell membranes or key enzymes of microorganisms, disrupting their normal functions.The unique structure of this compound can interact with cell membranes and key enzymes in microorganisms to disrupt their normal functions. Additionally, in studies related to plant growth regulation, certain derivatives of 1 - naphthylacrylic acid may have an impact on plant hormones or signal transduction pathways, influencing processes such as seed germination, root growth, and flowering.In studies on plant growth regulation, certain 1 - naphthylacrylic acids may also have an effect on plant hormones and signal transduction pathways. This could influence processes such as seed germination or root growth. This could potentially lead to the development of new agrochemicals to improve crop yields and quality.This could lead to the development new agrochemicals that improve crop yields and qualities. Overall, 1 - naphthylacrylic acid is a versatile compound with a wide range of applications across different scientific and technological fields.Overall, 1 – naphthylacrylic is a versatile chemical with many applications in different scientific and technical fields.

What are the properties of 1-Naphthylacrylic acid?

1 - Naphthylacrylic acid is an organic compound with distinct properties.1 - Naphthylacrylic Acid is an organic compound that has distinct properties.
Physical properties

In terms of appearance, 1 - Naphthylacrylic acid is typically a solid.In terms of appearance 1 - Naphthylacrylic Acid is typically a solid. Its melting point is an important physical characteristic.Its melting temperature is an important physical property. It has a relatively high melting point, which is related to the strength of the intermolecular forces within the solid structure.It has a high melting point which is correlated to the strength of intermolecular forces in the solid structure. The planar and conjugated nature of the naphthalene ring and the unsaturated acrylic acid moiety contribute to the close - packing of molecules in the solid state, resulting in a significant amount of energy required to break these interactions and transition to the liquid phase.The close-packed nature of the molecules in the solid phase is due to the planar and conjugated natures of the naphthalene rings and the unsaturated moiety of acrylic acid.

It has low solubility in water.It is not soluble in water. This is due to the hydrophobic nature of the large naphthalene ring.The hydrophobic nature is due to the large naphthalene rings. The naphthalene part of the molecule has only non - polar carbon - carbon and carbon - hydrogen bonds, which do not interact favorably with the polar water molecules through hydrogen bonding.The naphthalene ring has only non-polar carbon-carbon and carbon-hydrogen bonds. These do not interact well with the polar water molecule through hydrogen bonding. However, it shows better solubility in organic solvents such as ethanol, acetone, and chloroform.It is more soluble in organic solvents like ethanol, chloroform, and acetone. These organic solvents have similar non - polar or less polar regions that can interact with the non - polar parts of 1 - Naphthylacrylic acid through van der Waals forces, facilitating dissolution.These organic solvents contain non-polar or less-polar regions which can interact with 1 - Naphthylacrylic Acid through van der Waals force.

Chemical properties

1 - Naphthylacrylic acid contains a double bond in the acrylic acid part of the molecule.In the acrylic acid portion of the molecule, there is a double-bond. This double bond makes it reactive towards addition reactions.This double bond makes the molecule reactive to addition reactions. For example, it can undergo electrophilic addition reactions with substances like bromine.It can undergo electrophilic reactions with substances such as bromine. The double bond acts as a source of electrons, attracting electrophiles.The double bond attracts electrophiles by acting as a source for electrons. When bromine reacts with 1 - Naphthylacrylic acid, the double bond breaks, and two bromine atoms add across the double bond, forming a dibromo - derivative.When bromine reacts 1 - Naphthylacrylic Acid, the double bonds breaks and two bromines add across it, forming dibromo-derivatives.

The carboxylic acid group (-COOH) in 1 - Naphthylacrylic acid also imparts characteristic chemical reactivity.The carboxylic acid group in 1 - Naphthylacrylic Acid also imparts a characteristic chemical reactivity. It can participate in acid - base reactions.It can participate in acid-base reactions. In the presence of a base, such as sodium hydroxide, it donates a proton from the -COOH group to form a carboxylate salt.In the presence a base such as sodium hydroxide it donates a protons from the -COOH to form a carboxylate. This property allows it to be used in the synthesis of various esters.This property allows it be used in the synthesis for various esters. By reacting with an alcohol in the presence of an acid catalyst, it can form an ester through a condensation reaction, with the elimination of water.It can be converted into an ester by reacting with an acid catalyst and an alcohol.

The naphthalene ring also contributes to its chemical properties.The naphthalene rings also contribute to its chemical properties. It is a conjugated aromatic system, which makes it relatively stable due to resonance.It is a conjugated system, which makes resonance relatively stable. However, it can still undergo substitution reactions.It can still undergo substitute reactions. For instance, electrophilic aromatic substitution reactions can occur on the naphthalene ring.On the naphthalene rings, for example, electrophilic aromatic substitute reactions can occur. Substituents can be introduced to the ring, which can be useful in further functionalizing the molecule for various applications such as in the synthesis of dyes, pharmaceuticals, and other organic materials.Substituents may be introduced into the ring. This can be useful for further functionalizing the molecules in various applications, such as the synthesis and synthesis of organic materials, dyes, pharmaceuticals and other organic materials.

How is 1-Naphthylacrylic acid synthesized?

1 - Naphthylacrylic acid can be synthesized through the following general approach.The following general approach can be used to synthesize 1 - Naphthylacrylic Acid.
One common method is based on the Knoevenagel condensation reaction.Knoevenagel condensation is one common method. In this process, 1 - naphthaldehyde is used as a starting material.This process uses 1 - naphthaldehyde as a starter material. 1 - naphthaldehyde reacts with malonic acid in the presence of a suitable base catalyst.In the presence of an appropriate base catalyst, 1 - naphthaldehyde is reacted with malonic acid.

The reaction is typically carried out in an organic solvent.The reaction is usually carried out in a solvent organic. Pyridine is often a preferred base catalyst for this reaction.Pyridine is a common base catalyst used for this reaction. The role of the base is to deprotonate malonic acid, generating a reactive enolate anion.The base's role is to deprotonate the malonic acid and generate a reactive anion. This enolate anion then attacks the carbonyl carbon of 1 - naphthaldehyde.This enolate anion attacks the carbonyl atom of 1 -naphthaldehyde.

The initial product formed is an intermediate.The initial product is an intermediate. Subsequently, a decarboxylation reaction occurs.The decarboxylation occurs next. During decarboxylation, the carboxylic acid group from the malonic acid moiety that was added in excess is removed as carbon dioxide gas.During decarboxylation the carboxylic group from the malonic moiety that was over-added is removed as CO2 gas. This step is thermally driven, often achieved by heating the reaction mixture under reflux conditions.This step is driven by heat, and is often achieved through heating the reaction mixture in reflux conditions.

The overall reaction sequence results in the formation of 1 - naphthylacrylic acid.The overall reaction sequence leads to the formation of 1-naphthylacrylic acids. The refluxing conditions help to drive the reaction to completion by providing the necessary energy for the decarboxylation step and also facilitating the mixing of reactants.The refluxing conditions are important for driving the reaction forward by providing energy to the decarboxylation stage and also facilitating mixing of reactants.

After the reaction is complete, the crude product can be isolated.After the reaction has completed, the crude product is isolated. This usually involves first cooling the reaction mixture.This is usually done by cooling the reaction mixture first. Then, the product can be separated from the reaction mixture through techniques such as filtration if there are any solid by - products or unreacted starting materials.If there are solid by-products or unreacted starter materials, the product can then be separated from the mixture using techniques such as filtering. The product can further be purified.The product can be purified further. Recrystallization is a common purification method.Purification is often achieved by recrystallization. By choosing an appropriate solvent system, such as a mixture of ethanol and water, the impurities can be removed, and pure 1 - naphthylacrylic acid can be obtained in the form of well - defined crystals.By using a solvent system such as ethanol and water to remove impurities, pure 1 -naphthylacrylic can be obtained. This synthesis method allows for the preparation of 1 - naphthylacrylic acid with relatively good yields and purity, which is useful for various applications in the fields of organic synthesis, pharmaceuticals, and materials science.This method is a good way to prepare 1 - naphthylacrylic acids with high yields and purity. It can be used in various fields such as organic synthesis, pharmaceuticals and materials science.

What are the safety precautions when handling 1-Naphthylacrylic acid?

1 - Naphthylacrylic acid is a chemical compound, and when handling it, several safety precautions should be taken.When handling naphthylacrylic acids, it is important to take several safety precautions.
First, personal protective equipment is crucial.Personal protective equipment is essential. Wear appropriate protective clothing, such as long - sleeved laboratory coats or coveralls, to prevent skin contact.Wear protective clothing such as long-sleeved lab coats or coveralls to avoid skin contact. Chemical - resistant gloves made of materials like nitrile or neoprene should be worn.Wear chemical-resistant gloves made from materials such as nitrile and neoprene. These gloves can provide a barrier against the potential absorption of 1 - naphthylacrylic acid through the skin, which could cause skin irritation, allergic reactions, or other harmful effects.These gloves provide a barrier to the absorption of 1 – naphthylacrylic acids through the skin. This could cause skin irritations, allergic reactions or other harmful effects. Additionally, safety goggles or a face shield should be used to protect the eyes.Safety goggles or face shields should also be worn to protect the eyes. In case of any accidental splashing, the eyes are highly vulnerable to damage, and the goggles can prevent the chemical from coming into direct contact with the eyes, avoiding potential eye irritation, burns, or long - term vision problems.The eyes are particularly vulnerable to damage in the event of an accidental splash. Goggles will prevent the chemical from directly contacting the eyes and causing irritation, burning, or long-term vision problems.

Second, work in a well - ventilated area.Second, make sure that you are working in an area with good ventilation. 1 - Naphthylacrylic acid may release fumes or vapors, especially if heated or in a concentrated form.1 - Naphthylacrylic Acid may release fumes and vapors when heated or concentrated. Adequate ventilation, such as using a fume hood in a laboratory setting, helps to remove these potentially harmful fumes from the breathing zone.Adequate ventilation in a lab setting, such as the use of a fume-hood, can help remove these potentially dangerous fumes. This reduces the risk of inhaling the chemical, which could lead to respiratory problems, including irritation of the nose, throat, and lungs.This reduces the chance of inhaling the chemicals, which can lead to respiratory problems including irritation of the throat, nose, and lungs. Prolonged or high - level exposure through inhalation might even cause more serious respiratory disorders.Inhaling the chemical at high levels or for a long time could cause respiratory problems.

Third, when storing 1 - Naphthylacrylic acid, keep it in a cool, dry place away from sources of heat and ignition.Third, store 1 - Naphthylacrylic Acid in a cool and dry place, away from heat sources and ignition. It is important to store it in a properly labeled container to avoid confusion.To avoid confusion, it is important to store the acid in a container that is clearly labeled. If the chemical is stored near heat sources, it may decompose or even catch fire, especially if it is flammable or has a low flash point.If the chemical is kept near heat sources, then it can decompose, or even catch on fire, especially if the chemical is flammable, or has a very low flash point. Also, proper storage helps to maintain the chemical's stability and prevent leakage or spills.Proper storage also helps maintain the chemical's stability and prevents leaks or spills.

Fourth, in case of any spills, immediate action is required.In the event of spills, you must act immediately. First, evacuate the area to ensure the safety of everyone nearby.First, evacuate the surrounding area to ensure everyone's safety. Then, follow the proper spill - cleanup procedures.Follow the correct spill - cleaning procedures. Use absorbent materials like vermiculite, sand, or special spill - control kits to soak up the spilled 1 - Naphthylacrylic acid.To soak up 1 - Naphthylacrylic Acid, use absorbent materials such as vermiculite or sand. You can also use special spill-control kits. The contaminated absorbent should be placed in a sealed container and disposed of according to local regulations.The contaminated absorbent must be placed in a sealed bag and disposed according to local regulations. Do not wash the spill down the drain as it may contaminate water sources.Do not flush the spill down the sink as it could contaminate the water source.

Finally, be familiar with the first - aid procedures in case of exposure.Be familiar with the first-aid procedures in case you are exposed. If there is skin contact, immediately remove contaminated clothing and wash the affected area with plenty of water for at least 15 minutes.If skin contact occurs, remove all contaminated clothing immediately and wash the affected area for at least 15 mins with plenty of water. Seek medical attention if there are any signs of irritation or other adverse effects.If you notice any irritation or other adverse reactions, seek medical attention. In case of eye contact, flush the eyes with copious amounts of water for at least 15 minutes, lifting the eyelids occasionally, and then seek immediate medical help.If you have had eye contact, rinse your eyes with plenty of water for 15 minutes while lifting the eyelids periodically. Then, seek immediate medical attention. If inhaled, move to fresh air immediately, and if breathing is difficult, provide artificial respiration and call for emergency medical services.If inhaled move to fresh air as soon as possible. If breathing is difficult provide artificial respiration. Call emergency medical services.

What are the differences between 1-Naphthylacrylic acid and other similar compounds?

1 - Naphthylacrylic acid is a unique compound with several differences compared to other similar compounds.1 - Naphthylacrylic Acid is a unique chemical compound that differs from other similar compounds in several ways.
One key difference lies in its molecular structure.The molecular structure is the key difference. It contains a naphthalene ring fused to an acrylic acid moiety.It contains a naphthalene moiety fused to a naphthalene-ring. This naphthalene ring imparts distinct physical and chemical properties.This naphthalene rings imparts distinct chemical and physical properties. In contrast, many related compounds might have simpler aromatic rings like benzene.Many related compounds may have simpler aromatic rings, such as benzene. The naphthalene ring in 1 - naphthylacrylic acid provides greater conjugation, which affects its light - absorbing properties.The naphthalene rings in 1 - Naphthylacrylic Acid provide greater conjugation which affects the light-absorbing properties. Compounds with benzene rings usually have different absorption spectra, as the extended conjugation in naphthalene allows for absorption of light at longer wavelengths.Compounds containing benzene rings have different absorption spectrums, because the extended conjugation of naphthalene allows absorption at longer wavelengths.

In terms of solubility, 1 - naphthylacrylic acid's relatively large and non - polar naphthalene part makes it less soluble in water compared to some simpler acrylic acid derivatives with smaller non - polar groups.The relatively large non-polar naphthalene group in 1 - naphthylacrylic acids makes it less water-soluble than some other acrylic acid derivatives that have smaller non-polar groups. However, it may show better solubility in organic solvents like dichloromethane or ethyl acetate due to the lipophilic nature of the naphthalene ring.It may be more soluble in organic solvents such as dichloromethane and ethyl-acetate because of the lipophilic nature the naphthalene rings.

Reactivity is another area of difference.Reactivity is also a difference. The double bond in the acrylic acid part of 1 - naphthylacrylic acid is reactive towards addition reactions, similar to other acrylic acid - based compounds.The double bond of the acrylic acid in 1 - naphthylacrylic is reactive towards addition reactions. This is similar to other acrylic acids - based substances. But the presence of the naphthalene ring can influence the regioselectivity of these reactions.The naphthalene can affect the regioselectivity. For example, in electrophilic addition reactions, the electron - density distribution in the molecule, affected by the naphthalene ring, can direct the incoming electrophile to specific positions on the double bond.In electrophilic addition reactions for example, the electron-density distribution in the molecule can direct the incoming atom to specific positions of the double bond. This is different from compounds without the naphthalene ring where the reactivity is more straightforwardly determined by the acrylic acid functional group alone.This is different than compounds without the naphthalene rings, where the reactivity of the compound is determined more directly by the acrylic acid group.

In terms of biological activity, 1 - naphthylacrylic acid may exhibit unique effects.In terms of biological activity 1 - naphthylacrylic may have unique effects. The naphthalene ring can interact with biological receptors in a different way compared to simpler aromatic rings.The naphthalene rings can interact with biological receptors differently than simpler aromatic rings. Some studies have shown that compounds with naphthalene moieties can have specific binding affinities to certain proteins or enzymes, potentially leading to applications in drug discovery or as biological probes.Some studies have shown compounds with naphthalene moiety can have specific binding affinity to certain proteins or enzymes, which could lead to applications in drug development or as biological probes. This is in contrast to many common acrylic acid derivatives that may have more general - purpose biological activities or none at all.This is in contrast with many common acrylic acids derivatives which may have more general-purpose biological activities or none at.

Finally, in industrial applications, 1 - naphthylacrylic acid's properties make it suitable for different uses compared to similar compounds.In industrial applications, the properties of 1 - naphthylacrylic acids make it more suitable than similar compounds for different uses. Its light - absorbing properties can be exploited in the production of optical materials, while its reactivity can be utilized in the synthesis of specialty polymers.Its light-absorbing properties can also be used to produce optical materials. Meanwhile, its reactivity is useful in the synthesis and synthesis of specialty plastics. These applications may not be directly applicable to simpler acrylic acid - based compounds without the unique structural features of 1 - naphthylacrylic acid.These applications may be difficult to apply to simpler acrylic acid-based compounds, without the unique structure of 1 -naphthylacrylic acids.