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3-(2-thienyl)acrylic Acid


Properties
Product Name 3-(2-Thienyl)acrylic acid
Cas Number 4733-39-5
Formula C7H6O2S
Molar Mass 154.19
Boiling Point data not available
Melting Point data not available
Density data not available
Solubility data not available
Appearance data not available
Refractive Index data not available
Flash Point data not available
Stability data not available
Ph data not available
FAQ

What are the main applications of 3-(2-Thienyl)acrylic acid?

3-(2-Thienyl)acrylic acid has several main applications.There are several main uses for 3-(2-thienyl-acrylic acid).
In the field of organic synthesis, it serves as a valuable building block.It is a useful building block in organic synthesis. Its structure, with the thiophene ring and the acrylic acid moiety, provides unique reactivity.Its structure with the thiophene moiety and the acrylic acid ring provides unique reactivity. Chemists can use it to create more complex organic compounds.It can be used by chemists to create more complex organic molecules. For example, through reactions like esterification, the carboxylic acid group can be modified to form esters.Through reactions such as esterification, carboxylic acids can be converted to esters. These esters can then be further incorporated into larger molecules for various purposes, such as in the synthesis of polymers or in the creation of compounds with specific functional groups for pharmaceutical or material science research.These esters can be further incorporated into bigger molecules for various purposes. For example, in the synthesis or polymers or the creation of compounds that have specific functional groups in pharmaceutical or material science research.

In the pharmaceutical industry, 3-(2-Thienyl)acrylic acid and its derivatives show potential biological activities.In the pharmaceutical industry, 3- (2- Thienyl)acrylic acids and its derivatives have potential biological activities. Some derivatives have been investigated for their antibacterial, antifungal, or anti - inflammatory properties.Some derivatives were investigated for their antibacterial or antifungal properties. The thiophene ring is known to confer certain biological characteristics, and when combined with the acrylic acid structure, it may interact with biological targets in the body.When combined with the acrylic-acid structure, the thiophene rings are known to confer biological characteristics. This may allow them to interact with biological targets within the body. For instance, it could potentially interfere with the metabolic pathways of bacteria or fungi, leading to their growth inhibition.It could, for example, interfere with the metabolism of bacteria or fungi and inhibit their growth. Additionally, in anti - inflammatory research, compounds derived from 3-(2-Thienyl)acrylic acid might modulate the body's immune response by interacting with key proteins involved in the inflammatory cascade.In anti-inflammatory research, compounds derived 3-(2-Thienylacrylic acid) might modulate the immune response of the body by interacting with proteins involved in the inflammation cascade.

In the area of materials science, this compound can be used in the preparation of functional polymers.This compound can be used to prepare functional polymers in the field of materials science. By incorporating 3-(2-Thienyl)acrylic acid into a polymer backbone, the resulting polymer can have enhanced properties.The properties of a polymer can be enhanced by incorporating 3-(2-Thienyl-acrylic) acid into the polymer's backbone. The thiophene ring can contribute to the polymer's electronic properties, potentially making it suitable for applications in conductive polymers.The thiophene rings can contribute to electronic properties of the polymer, making it potentially suitable for applications as conductive polymers. These conductive polymers can be used in areas such as organic electronics, for example, in the manufacturing of organic light - emitting diodes (OLEDs) or sensors.These conductive materials can be used for organic electronics, such as the production of organic light-emitting diodes or sensors. The acrylic acid part can also participate in cross - linking reactions, which can improve the mechanical and thermal stability of the polymer, making it useful in coatings or packaging materials where durability is required.The acrylic acid can also be used to participate in cross-linking reactions that can improve the mechanical and thermostability of the polymer. This makes it useful for coatings or packaging materials when durability is needed.

In the field of agrochemicals, derivatives of 3-(2-Thienyl)acrylic acid may find applications as pesticides or plant growth regulators.Derivates of 3-(2-Thienylacrylic acid) may be used as plant growth regulators or pesticides in the field of agrochemicals. The unique chemical structure could have an impact on the growth and development of pests or plants.The unique chemical structure may have an effect on the growth and development or pests or plants. As a pesticide, it might disrupt the normal physiological functions of insects or other pests, protecting crops.As a pesticide it could disrupt the normal physiological functions in insects or other pests protecting crops. As a plant growth regulator, it could influence processes such as germination, flowering, or fruit set in plants, potentially increasing agricultural yields.As a plant growth regulatory, it could influence processes like germination, fruit set, or flowering in plants. This could increase agricultural yields.

What is the chemical structure of 3-(2-Thienyl)acrylic acid?

3-(2-Thienyl)acrylic acid is an organic compound with an interesting chemical structure.3-(2-Thienyl-)acrylic acid has an interesting chemical structure.
The core of its structure contains a thiophene ring.The core of the structure is a thiophene. Thiophene is a five - membered heterocyclic aromatic ring.The thiophene ring is a five-membered heterocyclic ring. It consists of four carbon atoms and one sulfur atom in the ring.It is made up of four carbon and one sulfur atoms. The carbon atoms in the thiophene ring are arranged in a planar, cyclic structure, and the sulfur atom contributes to the ring's aromaticity through its lone pair of electrons participating in the delocalized p - electron system.The carbon atoms of the thiophene rings are arranged in a cyclic, planar structure. The sulfur atom contributes the aromaticity of the ring through its single pair electrons that participate in the delocalized P-electrons system.

Attached to the 2 - position of the thiophene ring is an acrylic acid moiety.The acrylic acid moiety is attached to the 2 – position of the thiophene rings. The acrylic acid part contains a vinyl group (-CH=CH2) directly connected to a carboxylic acid group (-COOH).The acrylic acid moiety contains a vinyl group directly connected to a carboxylic group (-COOH). The double bond in the vinyl group is responsible for the compound's potential to participate in addition reactions.The double bond of the vinyl group is what gives the compound the ability to participate in additional reactions. The carboxylic acid group imparts acidic properties to the molecule.The carboxylic group gives the molecule its acidic properties. It can donate a proton in an appropriate environment due to the resonance - stabilized carboxylate anion that forms upon deprotonation.It can donate a pron in a suitable environment due to the resonance-stabilized carboxylate anion formed upon deprotonation.

Overall, in 3-(2 - Thienyl)acrylic acid, the thiophene ring and the acrylic acid part are linked together by a single bond at the 2 - position of the thiophene ring.In 3-(2 – Thienyl-acrylic acid), the thiophene and acrylic acid parts are linked by a single link at the 2 – position of the thiophene. This combination of the electron - rich and aromatic thiophene ring with the reactive and acidic acrylic acid group gives the compound unique chemical and physical properties.The combination of the aromatic and electron-rich thiophene rings with the reactive and acidic group of acrylic acid gives the compound its unique chemical and physical characteristics. These properties make it useful in various applications such as in the synthesis of pharmaceuticals, as well as in materials science where its double bond can be used for polymerization reactions to create new polymers with specific properties.These properties make the compound useful in a variety of applications, such as in pharmaceutical synthesis and materials science where it can be used to polymerize reactions to create polymers with specific characteristics. The compound's structure also allows for potential modifications by reacting either the double bond, the carboxylic acid group, or the thiophene ring itself, opening up opportunities for the development of a wide range of derivatives with tailored functions.The structure of the compound allows for a variety of modifications, including the reaction of the double bond with the carboxylic group or the thiophene rings themselves.

How is 3-(2-Thienyl)acrylic acid synthesized?

3-(2 - Thienyl)acrylic acid can be synthesized through the following general approach:The following general approach can be used to synthesize 3-(2 – Thienyl-)acrylic acid:
One common method involves the Knoevenagel condensation reaction.Knoevenagel condensation is a common method. In this reaction, 2 - thiophenecarboxaldehyde and malonic acid are used as starting materials.

The reaction is typically carried out in the presence of a base catalyst.The reaction is usually carried out in presence of a catalyst. Pyridine is often a suitable base for this reaction.This reaction is usually carried out in the presence of pyridine. The base activates malonic acid, which then reacts with 2 - thiophenecarboxaldehyde.

First, the base deprotonates malonic acid, generating a reactive enolate ion.The base first deprotonates the malonic acid to produce a reactive enolate anion. This enolate ion attacks the carbonyl carbon of 2 - thiophenecarboxaldehyde. A series of subsequent steps occur, including the formation of an intermediate.The formation of an intermediary is one of several steps that follow. Through a dehydration step, water is eliminated from the intermediate.The intermediate is dehydrated in a subsequent step. This dehydration leads to the formation of 3-(2 - Thienyl)acrylic acid.This dehydration results in the formation of 3-(2 -- Thienyl-)acrylic acid.

The reaction mixture is usually heated to an appropriate temperature to drive the reaction forward.The reaction mixture is heated to a temperature that will drive the reaction. The reaction temperature is carefully controlled, often in the range where the reaction proceeds at a reasonable rate without causing excessive side - reactions.The temperature of the reaction mixture is carefully controlled. It is usually in a range that allows the reaction to proceed at a reasonable pace without causing side reactions. For example, temperatures around 100 - 150 degC might be used, depending on the specific reaction conditions and the solvent employed.Temperatures between 100 and 150 degC may be used depending on the reaction conditions and solvent used.

After the reaction is complete, the product can be isolated and purified.After the reaction has completed, the product can then be isolated and purified. One common purification method is recrystallization.Recrystallization is a common method of purification. The crude product is dissolved in a suitable solvent, such as ethanol or a mixture of solvents.The crude product is dissolved into a suitable solvent such as ethanol, or a mixture. As the solution cools, pure 3-(2 - Thienyl)acrylic acid crystallizes out, leaving impurities in the solution.As the solution cools down, the pure 3-(2 Thienyl-acrylic) acid crystallizes, leaving the impurities behind. Filtration is then used to collect the purified crystals.The crystals are then collected by filtration.

Another possible synthetic route could involve the use of other aldehyde - acid - based condensations with modifications in reaction conditions, starting materials' substitution patterns, or the use of different catalysts to optimize the yield and purity of 3-(2 - Thienyl)acrylic acid.Another possible route would be to use other aldehyde-based condensations, with modifications to the reaction conditions, the starting materials' substitution patterns or the use different catalysts in order optimize the yield and purity for 3-(2 – Thienyl-)acrylic acid. However, the Knoevenagel condensation remains a straightforward and widely used approach for its synthesis.Knoevenagel condensation is a simple and widely used method for its synthesis.

What are the physical properties of 3-(2-Thienyl)acrylic acid?

3-(2-Thienyl)acrylic acid is a compound with distinct physical properties.3-(2-Thienyl-)acrylic acid has distinct physical properties.
Appearance: It typically exists as a solid.Appearance: It is usually a solid. Usually, it is presented in the form of fine crystals or a powder.It is usually presented as fine crystals or powder. The color can range from white to off - white, which is common for many organic solids in their pure form.The color can vary from off-white to white, as is common with many organic solids. This appearance makes it easy to handle and identify in a laboratory setting.This makes it easy to identify and handle in a lab setting.

Melting Point: The melting point of 3-(2 - Thienyl)acrylic acid is an important physical property.Melting Point: The melting of 3-(2 Thienyl-acrylic acid) is an important property. It has a relatively well - defined melting point within a certain temperature range.It has a fairly well-defined melting point within a specific temperature range. Precise values can vary slightly depending on factors such as purity, but generally, it melts at a temperature that allows for thermal analysis techniques to be used for identification and purity determination.The exact values can vary depending on factors like purity, but in general, it melts when a temperature is reached that allows thermal analysis to be used to identify and determine purity. The melting process is endothermic, meaning it absorbs heat as it transitions from the solid to the liquid state.The melting process is endothermic. This means that it absorbs heat when it transitions from a solid state to a liquid state. This property is useful in quality control and in understanding the compound's behavior under heat.This property is helpful in quality control, and to understand the compound's behavior when heated.

Solubility: In terms of solubility, 3-(2 - Thienyl)acrylic acid shows different behaviors in various solvents.Solubility: 3-(2 – Thienyl-)acrylic acid has different solubility in different solvents. It has limited solubility in non - polar solvents like hexane due to the polar nature of the carboxylic acid functional group present in the molecule.It is not soluble in non-polar solvents such as hexane because of the polarity of the carboxylic functional group in the molecule. However, it is more soluble in polar organic solvents such as ethanol, methanol, and dimethyl sulfoxide (DMSO).It is more soluble when it comes to polar organic solvents like ethanol, methanol and dimethyl sulfoxide. The carboxylic acid group can form hydrogen bonds with polar solvents, facilitating dissolution.The carboxylic group can form hydrogen bond with polar solvents to facilitate dissolution. In water, its solubility is relatively low but can be increased by adjusting the pH.Its solubility in water is relatively low, but it can be increased by adjusting pH. At higher pH values, the carboxylic acid group ionizes, forming a carboxylate anion, which greatly enhances its solubility in water.At higher pH values the carboxylic group ionizes and forms a carboxylate anion, which greatly increases its solubility.

Density: The density of 3-(2 - Thienyl)acrylic acid is another physical characteristic.Another physical characteristic is density. The density is determined by the mass - to - volume ratio of the compound.The mass-to-volume ratio of the compound determines the density. While the exact density value is specific to the pure compound under standard conditions, it is influenced by factors like crystal packing in the solid state.The exact density value of a pure compound is determined by standard conditions. However, factors such as crystal packing can influence the density. Knowledge of the density can be useful in applications where precise amounts of the compound need to be measured by volume, for example, in formulating solutions.The density is useful for applications that require precise measurements of volume of the compound, such as formulating solutions.

Boiling Point: Since 3-(2 - Thienyl)acrylic acid typically decomposes before reaching a true boiling point, this property is often less straightforward to define.Boiling point: Because 3-(2 – Thienyl-)acrylic acid decomposes prior to reaching a true vapor pressure, this property can be difficult to define. Thermal decomposition occurs due to the breakdown of the chemical structure under high heat.Thermal decomposition is caused by the breakdown of a chemical structure when heated to high temperatures. Understanding this decomposition behavior is crucial when considering processes that might subject the compound to elevated temperatures.Understanding the decomposition behavior of a compound is important when considering processes which might subject it to elevated temperatures.

In conclusion, the physical properties of 3-(2 - Thienyl)acrylic acid, including appearance, melting point, solubility, density, and decomposition behavior, play vital roles in its handling, identification, and use in various chemical processes and applications.The physical properties of 3-(2- Thienyl )acrylic acid such as appearance, melting point and solubility, density and decomposition behavior play a vital role in its handling, identification and use in different chemical processes and applications.

What are the safety precautions when handling 3-(2-Thienyl)acrylic acid?

When handling 3-(2 - Thienyl)acrylic acid, several safety precautions are necessary.Safety precautions must be taken when handling 3-(2 -- Thienyl-)acrylic acid.
First, in terms of personal protective equipment.Personal protective equipment is the first thing to consider. Wear appropriate chemical - resistant gloves.Wear gloves that are resistant to chemicals. Nitrile gloves are often a good choice as they can provide a certain level of protection against the contact of this chemical with the skin.Nitrile gloves can offer a level of protection from the chemical. Skin contact may cause irritation, and some individuals might be more sensitive, so the gloves act as a barrier.The gloves can act as a barrier to prevent skin irritation. Some people are more sensitive than others, so they may be more susceptible. Additionally, put on safety goggles.Wear safety goggles as well. These are crucial to prevent any splashes of 3-(2 - Thienyl)acrylic acid from getting into the eyes.They are essential to prevent any splashes or splatters of 3-(2 Thienyl-acrylic) acid from getting in the eyes. If it enters the eyes, it can lead to serious eye irritation, potentially causing damage to the cornea and other eye tissues.If it gets into the eyes, it could cause serious irritation and damage to the cornea or other eye tissues. A lab coat or apron should also be worn to protect clothing from spills and splashes, reducing the risk of skin exposure through contaminated clothing.Wearing a lab coat or an apron will protect clothing from spills, splashes and contaminates.

Second, when working with this chemical in a laboratory or industrial setting, ensure proper ventilation.When working with this chemical, it is important to ensure that the area is properly ventilated. 3-(2 - Thienyl)acrylic acid may give off fumes, especially when heated or during certain chemical reactions.3-(2 – Thienyl-)acrylic acid can emit fumes when heated or during chemical reactions. A well - ventilated area, preferably with a fume hood, helps to remove these fumes.These fumes can be removed by a well-ventilated area, preferably equipped with a fumehood. This is important because inhaling these fumes can irritate the respiratory tract.Inhaling these fumes may irritate your respiratory tract. Prolonged or high - level inhalation might lead to more serious respiratory problems such as coughing, shortness of breath, and in severe cases, damage to the lungs.Inhaling fumes at high levels or for a long time can cause respiratory problems, such as coughing and shortness of breathe. In severe cases, the lungs may be damaged.

Third, when storing 3-(2 - Thienyl)acrylic acid, keep it in a cool, dry place away from sources of ignition.Third, store 3-(2 – Thienyl-)acrylic acid in a dry, cool place, away from ignition sources. Although it may not be highly flammable under normal conditions, like many organic compounds, it could potentially pose a fire risk if exposed to high heat or open flames.It may not be highly explosive under normal conditions but it can cause a fire if exposed to heat or open flames. Store it in a properly labeled container to avoid confusion with other chemicals.Store it in a container that is clearly labeled to avoid confusion with any other chemicals. Misidentification could lead to dangerous chemical reactions if it is accidentally mixed with incompatible substances.If it is accidentally mixed up with other chemicals, a misidentification can lead to dangerous chemical reactions.

Fourth, in case of accidental exposure, know the appropriate first - aid measures.In the event of accidental exposure to a substance, you should know what first-aid measures to take. If there is skin contact, immediately wash the affected area with plenty of water for at least 15 minutes.If skin contact occurs, wash the affected area immediately with plenty of water and for at least 15 min. Remove any contaminated clothing during this process.During this process, remove any contaminated clothing. If it gets into the eyes, flush the eyes with copious amounts of water for at least 15 minutes and seek immediate medical attention.If it gets in the eyes, flush them with plenty of water for 15 minutes at least and seek immediate medical care. In case of inhalation, move to fresh air immediately.In the event of inhalation, you should move to fresh air as soon as possible. If breathing is difficult, provide oxygen and call for medical help.If breathing is difficult provide oxygen and contact medical help. If ingestion occurs, do not induce vomiting unless instructed by a medical professional.In the event of ingestion, do not induce vomiting without medical advice. Instead, rinse the mouth with water and seek medical assistance promptly.Rinse the mouth with water instead and seek immediate medical attention.