What is the chemical structure of 3-(3,5-Difluorophenyl)acrylic acid?

3-(3,5-Difluorophenyl)acrylic acid is an organic compound. Let's break down its chemical structure description.Let's look at its chemical structure.
First, consider the phenyl group.Consider the phenyl ring. A phenyl group is a six - membered aromatic ring composed of carbon atoms with alternating single and double bonds.A phenyl ring is a six-membered aromatic ring made up of carbon atoms alternating between single and double bonds. In this case, it is a 3,5 - difluorophenyl group.In this case it is a 3,5 - difluorophenyl ring. '3,5 - di' indicates that there are two fluorine atoms attached to the phenyl ring.The '3,5-di' indicates that two fluorine molecules are attached to the phenyl rings. The fluorine atoms are located at the 3 - and 5 - positions of the phenyl ring.The fluorine is located at the 3 and 5 positions of the phenyl rings.

Next, the 'acrylic acid' part of the name gives us another clue.The 'acrylic' part of the title gives us another clue. Acrylic acid has a structure where there is a carboxyl group (-COOH) attached to a vinyl group (-CH=CH2).Acrylic acid is a substance that has a carboxyl (-COOH), attached to a vinyl (-CH=CH2). A carboxyl group consists of a carbonyl group (C=O) and a hydroxyl group (-OH) attached to the same carbon atom.A carboxyl group is made up of a carbonyl (C=O), and a hydroxyl (-OH), both attached to the same carbon. The vinyl group is an unsaturated hydrocarbon group with a carbon - carbon double bond.The vinyl group is a hydrocarbon unsaturated group with a double carbon-carbon bond.

When we combine these two parts to form 3-(3,5 - difluorophenyl)acrylic acid, the 3,5 - difluorophenyl group is attached to the vinyl group of the acrylic acid moiety. Specifically, the attachment occurs at the carbon atom of the vinyl group that is not part of the double bond.The attachment occurs at the carbon of the vinyl group which is not part the double bond.

So, overall, the chemical structure of 3-(3,5 - difluorophenyl)acrylic acid has a 3,5 - difluorophenyl group connected to a carbon atom which is also part of a vinyl group. The other carbon of the vinyl group is double - bonded to another carbon, and this carbon is in turn part of a carboxyl group.The other carbon atom of the vinyl group has a double-bond to another carbon atom, which is part of a carboxyl atom. This compound combines the properties of the fluorine - containing aromatic phenyl group with the reactivity associated with the unsaturated vinyl and acidic carboxyl groups, which can be useful in various chemical reactions and applications such as in the synthesis of pharmaceuticals or polymers.This compound combines the properties associated with the aromatic phenyl group containing fluorine with the reactivity of the unsaturated vinyl groups and acidic carboxyls. It can be used in various chemical reactions or applications, such as the synthesis of polymers or pharmaceuticals.

What are the applications of 3-(3,5-Difluorophenyl)acrylic acid?

3-(3,5 - Difluorophenyl)acrylic acid is a compound with potential applications in several fields.
In the pharmaceutical industry, it can serve as an important intermediate.It can be used as an intermediate in the pharmaceutical industry. Its unique structure with the difluorophenyl group and the acrylic acid moiety allows for the synthesis of novel drugs.Its unique structure, with the difluorophenyl moiety and the acrylic acid group, allows for the synthesise of novel drugs. Fluorine - containing compounds often have enhanced biological activities due to the small size and high electronegativity of fluorine atoms.Fluorine-containing compounds have increased biological activity due to their small size and high electronegativity. The acrylic acid part can participate in various chemical reactions to form different pharmacologically active substances.Acrylic acid can be used in a variety of chemical reactions to produce different pharmacologically-active substances. For example, it may be used to create drugs targeting specific receptors or enzymes.It can be used to make drugs that target specific enzymes or receptors. Compounds derived from 3-(3,5 - Difluorophenyl)acrylic acid could potentially be developed into anti - inflammatory drugs. By modifying the structure further through chemical reactions, it might be possible to design molecules that can interact with key proteins involved in the inflammatory pathways, blocking their action and thus reducing inflammation.By further modifying the structure through chemical reactions, it may be possible to design molecules which can interact with key protein involved in the inflammatory pathway, blocking their actions and reducing inflammation.

In the field of materials science, 3-(3,5 - Difluorophenyl)acrylic acid can be used in the preparation of specialty polymers. When copolymerized with other monomers, it can introduce unique properties to the polymer.It can be copolymerized to give the polymer unique properties. The fluorinated phenyl group can improve the polymer's hydrophobicity, chemical resistance, and thermal stability.The fluorinated group can improve the polymer’s hydrophobicity and chemical resistance. For instance, in coatings applications, polymers containing this compound could be used to create coatings that are more resistant to moisture, chemicals, and wear.Polymers containing the compound can be used in coatings to create coatings more resistant to chemicals, moisture, and wear. These coatings could be applied on various substrates such as metals, plastics, and ceramics.These coatings can be applied to a variety of substrates including metals, ceramics, and plastics. In the case of metal coatings, they can prevent corrosion by providing a protective layer with enhanced barrier properties due to the hydrophobic nature imparted by the fluorine - containing moiety.Metal coatings can be used to prevent corrosion due to their hydrophobic properties.

Moreover, in the area of organic synthesis, 3-(3,5 - Difluorophenyl)acrylic acid is a valuable building block. It can participate in reactions like Michael addition, Diels - Alder reactions, and Heck reactions.It can be used in reactions such as Michael addition, Diels-Alder reactions, or Heck reactions. Through these reactions, chemists can construct more complex organic molecules with diverse structures and functions.Chemists can create more complex organic molecules that have diverse structures and functions through these reactions. For example, in the synthesis of natural product - like compounds, the acrylic acid double bond can be used to build the carbon - carbon framework, while the difluorophenyl group can act as a directing group or contribute to the overall biological activity of the final product.In the synthesis of natural products - like compounds the acrylic acid double bonds can be used to construct the carbon-carbon framework, whereas the difluorophenyl groups can act as a leading group or contribute to overall biological activity of final product. This compound thus provides a starting point for the creation of a wide range of organic compounds with potential applications in many different areas including agrochemicals, dyes, and fragrances.This compound can be used to create a variety of organic compounds that have potential applications in a range of different areas, including agrochemicals and dyes.

What are the properties of 3-(3,5-Difluorophenyl)acrylic acid?

3-(3,5-Difluorophenyl)acrylic acid is an organic compound with specific properties.
Physical properties:Physical Properties
It is likely to exist as a solid at room temperature.At room temperature, it is likely to be a solid. The melting point is an important characteristic.The melting point is a very important characteristic. Precise determination of the melting point can help in identifying and purifying the compound.The melting point can be determined precisely to help identify and purify the compound. Melting point data can also give an indication of the compound's purity; a pure sample typically has a narrow melting point range.The melting point can also be used to determine the purity of a compound; a pure sample will have a narrow range. Regarding solubility, it is sparingly soluble in water due to the non - polar nature of the fluorinated phenyl group and the relatively small size of the polar carboxylic acid group.It is only sparingly soluble due to the non-polar nature of fluorinated groups and the relative small size of carboxylic acid groups. However, it is more soluble in organic solvents such as ethanol, methanol, and dichloromethane.It is more soluble when it comes to organic solvents like ethanol, dichloromethane, and methanol. These solvents can interact with the molecule through van der Waals forces and hydrogen - bonding (in the case of alcohols), facilitating dissolution.These solvents can interact directly with the molecule via van der Waals forces or hydrogen-bonding (in the cases of alcohols), which facilitates dissolution.

Chemical properties:Chemical properties
The carboxylic acid functional group (-COOH) is highly reactive.The carboxylic acid functional groups (-COOH), is highly reactive. It can undergo acid - base reactions.It can undergo acid-base reactions. For example, when reacted with a base such as sodium hydroxide (NaOH), it will form a salt, 3-(3,5 - difluorophenyl)acrylate sodium salt, and water. This reaction is typical of carboxylic acids and can be used in the separation and purification processes of the compound.This reaction is characteristic of carboxylic acid and can be used to separate and purify the compound. The double bond in the acrylic acid part of the molecule is also reactive.The double bond of the acrylic acid molecule is also reactive. It can participate in addition reactions.It can be involved in addition reactions. For instance, it can react with bromine (Br2) in an addition reaction across the double bond, forming a dibromo - derivative.It can, for example, react with bromine in an addition reaction, across the double bonds, to form a dibromo-derivative. This reactivity makes 3-(3,5 - difluorophenyl)acrylic acid useful in organic synthesis, where it can be incorporated into larger molecules. The fluorine atoms on the phenyl ring also influence the chemical properties.The fluorine on the phenyl rings also influences the chemical properties. Fluorine is highly electronegative, which can withdraw electron density from the phenyl ring.Fluorine, being highly electronegative can remove electron density from phenyl rings. This affects the reactivity of the aromatic ring, making it less reactive towards electrophilic aromatic substitution reactions compared to a non - fluorinated phenyl ring.This reduces the reactivity and reactivity towards electrophilic aromatic substitute reactions of the aromatic ring compared to non-fluorinated phenyl rings. In addition, the fluorine atoms can also influence the intermolecular forces, such as increasing the strength of van der Waals interactions due to their small size and high electronegativity.Fluorine atoms also have an effect on intermolecular interactions, increasing the strength of van der Waals interaction due to their small size. Overall, these physical and chemical properties make 3-(3,5 - difluorophenyl)acrylic acid a valuable compound in research and potentially in the development of new materials or pharmaceuticals.

How is 3-(3,5-Difluorophenyl)acrylic acid synthesized?

3-(3,5-Difluorophenyl)acrylic acid can be synthesized through several methods. One common approach involves a series of chemical reactions starting from appropriate starting materials.One common method involves a series chemical reactions that begin with appropriate starting materials.
First, 3,5 - difluorobenzaldehyde is often used as a key starting compound.As a starting compound, 3,5-difluorobenzaldehyde can be used. It can react with a compound containing an active methylene group, such as malonic acid, in the presence of a base.It can react in the presence a base with a compound that contains an active methylene, such as malonic acids. This reaction is known as the Knoevenagel condensation.This reaction is called the Knoevenagel condensate. The base catalyzes the reaction, facilitating the formation of a carbon - carbon double bond.The base catalyzes this reaction, facilitating a double carbon-carbon bond. During this reaction, the malonic acid loses a molecule of carbon dioxide.During this reaction the malonic acid loses one molecule of CO2. The reaction conditions typically require a suitable solvent, such as pyridine or a mixture of organic solvents, and a certain temperature range, usually around 80 - 120 degrees Celsius.The reaction conditions usually require a suitable solvant, such as pyridine, or a mixture organic solvents. They also require a temperature range of around 80-120 degrees Celsius.

Another method could involve the reaction of 3,5 - difluorophenylacetonitrile with an aldehyde in the presence of a base. The initial product formed is an intermediate that can be further hydrolyzed to obtain the 3-(3,5 - difluorophenyl)acrylic acid. The hydrolysis step usually requires the use of an acid or a base catalyst in an aqueous - organic solvent mixture.In order to perform the hydrolysis, an acid or base catalyst is usually used in a mixture of aqueous and organic solvents.

If using a more modern approach, palladium - catalyzed cross - coupling reactions can also be considered.Palladium-catalyzed cross-coupling reactions are also possible if you use a modern approach. For example, a pre - functionalized 3,5 - difluorophenyl halide can react with an acrylate derivative under palladium - catalyzed conditions.Palladium-catalyzed conditions can be used to react a pre-functionalized 3,5 – difluorophenylhalide with an acrylate derivate. This reaction requires specific ligands and reaction conditions to ensure high selectivity and yield.To ensure high selectivity, this reaction requires specific ligands as well as reaction conditions. The reaction is carried out in an inert atmosphere, often using solvents like dimethylformamide or toluene.The reaction takes place in an inert environment, using solvents such as dimethylformamide and toluene.

After the synthesis step, the crude product usually needs purification.Purification is usually required after the synthesis. This can be achieved through methods such as recrystallization from a suitable solvent system, like a mixture of ethanol and water.This can be done by recrystallization using a suitable solvent, such as a mixture of water and ethanol. Column chromatography can also be used if the impurities are more complex.If the impurities present are more complex, column chromatography may be used. The purity of the final 3-(3,5 - difluorophenyl)acrylic acid can be determined using techniques such as nuclear magnetic resonance spectroscopy and high - performance liquid chromatography. These steps are crucial to obtain a high - quality product suitable for various applications, whether it is for pharmaceutical research, material science, or other chemical processes.These steps are essential to obtaining a high-quality product that can be used for a variety of applications, such as pharmaceutical research, materials science, and other chemical processes.

What are the safety precautions when handling 3-(3,5-Difluorophenyl)acrylic acid?

When handling 3-(3,5 - Difluorophenyl)acrylic acid, several safety precautions are necessary.
First, in terms of personal protective equipment.Personal protective equipment is the first thing to consider. Wear appropriate protective clothing.Wear protective clothing. This includes a lab coat or similar full - body covering to prevent contact with the skin.Wear a labcoat or other full-body covering to protect the skin. The acid could potentially cause skin irritation, burns, or allergic reactions.The acid can cause skin irritations, burns or allergic reactions. Gloves made of a suitable chemical - resistant material, such as nitrile gloves, should be worn.Gloves made from a chemical-resistant material, such as Nitrile gloves, are recommended. These gloves can effectively block the acid from coming into direct contact with the hands.These gloves will prevent the acid from directly contacting the hands.

Eye protection is also crucial.Eye protection is equally important. Safety goggles or a face shield should be worn at all times during handling.Wear safety goggles or face shields at all times when handling the acid. If the acid splashes into the eyes, it can cause severe damage, including corneal burns and potential loss of vision.If the acid splashes in the eyes, it could cause severe damage including corneal burning and possible loss of vision.

Second, work in a well - ventilated area.Second, make sure that you are working in an area with good ventilation. 3-(3,5 - Difluorophenyl)acrylic acid may release fumes that can be irritating to the respiratory system. A fume hood is the ideal workspace as it can effectively capture and exhaust any harmful vapors.A fume hood can capture and exhaust harmful vapors. If a fume hood is not available, ensure the general laboratory ventilation is sufficient to keep the air fresh and reduce the concentration of any potentially harmful gases.If a fume-hood is not available, make sure the laboratory ventilation is adequate to keep the air clean and reduce the concentrations of potentially harmful gases.

Third, be careful during the transfer and storage of the acid.Third, take care when transferring and storing the acid. When transferring the acid from one container to another, use appropriate funnels and ensure a slow and controlled pour to prevent splashing.Use funnels to transfer the acid from one container into another. Pour slowly and controllably to avoid splashing. For storage, keep it in a tightly - sealed container in a cool, dry place away from sources of heat and ignition.Store it in a tightly-sealed container in a cool and dry location away from heat sources and ignition. Also, store it separately from incompatible substances.Store it away from other substances that are incompatible. For example, avoid storing it near strong bases as they can react violently with the acid.Avoid storing it near bases that can react violently.

Fourth, in case of contact.Fourth, if you come into contact with the acid. If the acid comes into contact with the skin, immediately rinse the affected area with copious amounts of water for at least 15 minutes.If the acid has come into contact with your skin, rinse it immediately with plenty of water. Do this for at least 15 min. Then, remove any contaminated clothing and seek medical attention.Remove any contaminated clothing, and seek medical attention. If it gets into the eyes, immediately flush the eyes with running water for at least 15 minutes, holding the eyelids open, and seek urgent medical help.If it gets in the eyes, flush them with running water while holding the eyelids wide open for at least 15 minute. Seek urgent medical attention. If inhaled, move to fresh air immediately.If inhaled immediately move to fresh air. If the person is experiencing difficulty breathing, provide artificial respiration if trained to do so and call for medical assistance.If the person has difficulty breathing, if you are trained to do this, provide artificial ventilation and call for medical help.

Finally, clean up any spills promptly.Lastly, clean up spills as soon as possible. Use absorbent materials like sand or vermiculite to soak up the spilled acid.To absorb the acid, use absorbent materials such as sand or Vermiculite. Then, carefully collect the contaminated absorbent and dispose of it according to local regulations.Then, carefully remove the contaminated absorbent from the area and dispose of it in accordance with local regulations. The spill area should be thoroughly washed with a suitable neutralizing agent and then rinsed with water.The spill area must be thoroughly cleaned with a neutralizing agent, followed by rinsing with water.