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Product Name | 3-(3-Furyl)acrylic acid |
Cas Number | 1188-36-3 |
Formula | C7H6O3 |
Molar Mass | 138.12 g/mol |
Density | 1.234 g/cm3 |
Boiling Point | 312.3 °C |
Melting Point | 118-120 °C |
Solubility | Soluble in organic solvents |
Appearance | White to beige crystalline powder |
Pka | 4.54 |
Refractive Index | 1.567 |
Flash Point | 143.8 °C |
Stability | Stable under recommended storage conditions |
Usage | Used in organic synthesis and as an intermediate |
What are the applications of 3-(3-Furyl)acrylic acid?
3-(3-Furyl)acrylic acid has several important applications.There are many applications for 3-(3-Furylacrylic acid).
One significant area is in the field of organic synthesis.Organic synthesis is a significant area. It serves as a valuable building block for creating more complex organic compounds.It is a useful building block to create more complex organic compounds. Its unique structure, with the furyl group and the acrylic acid moiety, allows chemists to perform various chemical reactions.The furyl group and acrylic acid moiety in its unique structure allows chemists perform a variety of chemical reactions. For example, through esterification reactions, it can be converted into esters.It can be converted to esters, for example, by esterification reactions. These esters can then be used in the synthesis of flavors and fragrances.These esters are then used to synthesize flavors and fragrances. The furyl - containing esters often possess interesting olfactory properties, adding a distinct and pleasant aroma to products like perfumes and scented candles.Furyl-containing esters are often olfactory compounds that add a pleasant and distinct aroma to products such as perfumes and scented candle.
In the pharmaceutical industry, 3-(3 - Furyl)acrylic acid also has potential.The pharmaceutical industry also has potential for 3-(3-Furyl)acrylic acid. It can be utilized as an intermediate in the synthesis of drugs.It can be used as an intermediate for the synthesis of pharmaceuticals. Some derivatives of this compound may exhibit biological activities.Some derivatives may have biological activity. For instance, they could potentially have anti - inflammatory or antioxidant properties.They could, for example, have anti-inflammatory or antioxidant properties. By modifying the structure of 3-(3 - Furyl)acrylic acid, chemists can develop molecules that interact with specific biological targets in the human body, leading to the development of new medications.By modifying 3-(3-Furyl)acrylic acid's structure, chemists are able to develop molecules that interact specifically with biological targets within the human body. This can lead to the development of novel medications.
Another application lies in the production of polymers.Polymers are another application. When copolymerized with other monomers, 3-(3 - Furyl)acrylic acid can introduce unique properties to the resulting polymers.Copolymerized with monomers other than 3-(3- Furyl)acrylic acids, the resulting polymers can have unique properties. The furyl group can enhance the thermal stability of the polymer.The furyl group may enhance the polymer's thermal stability. Additionally, it may improve the polymer's solubility in certain solvents, which is beneficial in applications such as coatings.It may also improve the polymer’s solubility in some solvents, which can be beneficial for applications such as coatings. Coatings made from polymers containing 3-(3 - Furyl)acrylic acid could have better adhesion properties to various substrates, protecting them from corrosion and wear.Coatings containing 3-(3-Furyl)acrylic acid may have better adhesion to substrates, protecting against corrosion and wear.
In the area of materials science, 3-(3 - Furyl)acrylic acid can be used to prepare functional materials.In the field of materials science, 3-(3-Furyl)acrylic acid is used to prepare functional material. For example, it can be incorporated into porous materials.It can be incorporated, for example, into porous materials. The acidic group can participate in ion - exchange processes, while the furyl group can interact with other molecules through p - p stacking interactions.The acidic group is able to participate in ion-exchange processes, while furyl can interact with other molecules via p-p stacking interactions. This makes these materials useful for applications such as selective adsorption of certain molecules from a mixture, which is important in separation technologies.These materials are useful for applications like selective adsorption, which is crucial in separation technologies.
Overall, 3-(3 - Furyl)acrylic acid is a versatile compound with a wide range of applications in organic synthesis, pharmaceuticals, polymers, and materials science, making it an important substance in these fields.Overall, 3-(3-Furyl)acrylic acid has a wide range applications in organic synthesis and pharmaceuticals. It is also used in polymers and materials science.
What are the physical and chemical properties of 3-(3-Furyl)acrylic acid?
3-(3 - Furyl)acrylic acid is an organic compound with certain distinct physical and chemical properties.3-(3-Furyl)acrylic Acid is an organic compound that has distinct physical and chemical characteristics.
Physical Properties
Appearance: It typically exists as a solid.Appearance: Typically, it is a solid. In its pure form, it is often a white to off - white crystalline powder.In its pure form it is usually a white or off-white crystalline powder. This crystalline nature is due to the regular arrangement of its molecules held together by intermolecular forces.This crystalline structure is due to its regular arrangement of molecules, which are held together by intermolecular force.
Melting Point: The melting point of 3-(3 - Furyl)acrylic acid is an important physical characteristic.Melting Point The melting point of 3-(3- Furyl)acrylic is an important physical property. It usually melts within a specific temperature range.It usually melts in a certain temperature range. Precise melting point data can be used for identification and purity determination.For identification and purity determination, melting point data is useful. For this compound, the melting point is around 141 - 143 degC.The melting point of this compound is between 141 and 143 degrees Celsius. This relatively high melting point is a result of the strong intermolecular forces, such as hydrogen bonding and van der Waals forces, that hold the molecules in a solid - state lattice.This high melting point is due to the strong intermolecular interactions, such as hydrogen bonds and van der Waals, which hold the molecules together in a solid-state lattice.
Solubility: In terms of solubility, 3-(3 - Furyl)acrylic acid shows some interesting behavior.Solubility: 3-(3-Furyl)acrylic shows an interesting solubility. It is sparingly soluble in water.It is only sparingly soluble. The reason for this limited solubility in water is that the compound has a relatively large non - polar furyl and acrylic acid moieties.This is due to the fact that the compound contains a large amount of non-polar furyl and acrylic acid moieties. Water is a highly polar solvent, and the non - polar parts of 3-(3 - Furyl)acrylic acid do not interact favorably with water molecules through hydrogen bonding.Water is a highly-polar solvent and the non-polar parts of 3-(3-Furyl)acrylic acids do not interact well with water molecules via hydrogen bonding. However, it is more soluble in organic solvents such as ethanol, methanol, and acetone.It is more soluble when it's dissolved in organic solvents like acetone, ethanol, or methanol. These organic solvents have similar polarity or can interact with the functional groups of the compound through various intermolecular forces, facilitating dissolution.These organic solvents can interact with functional groups in the compound by using intermolecular forces or have similar polarity.
Chemical Properties
Acidity: As an acrylic acid derivative, 3-(3 - Furyl)acrylic acid has acidic properties.Acidity: 3-(3-Furyl)acrylic acid is an acrylic acid derivative with acidic properties. The carboxylic acid group (-COOH) in the molecule can donate a proton in an aqueous solution or in the presence of a base.The carboxylic group (-COOH), which is part of the molecule, can donate a proton in an aqueous or base solution. This acidic behavior is due to the resonance stabilization of the carboxylate anion formed after the loss of a proton.This acidic behavior occurs due to the resonance stabilization the carboxylate anion after the loss a proton. The pKa value of the carboxylic acid group in 3-(3 - Furyl)acrylic acid can be measured, and it is in the range typical for carboxylic acids.The pKa of the carboxylic group in 3-(3-Furyl)acrylic acid is measurable and falls within the typical range for carboxylics. This acidity allows the compound to react with bases to form salts.This acidity allows for the compound to react to bases to form salts. For example, when reacted with sodium hydroxide (NaOH), it forms the corresponding sodium salt and water.When it reacts with sodium hydroxide, it forms the sodium salt and water.
Double - Bond Reactivity: The presence of a carbon - carbon double bond in the acrylic acid part of the molecule gives 3-(3 - Furyl)acrylic acid the ability to undergo addition reactions.Double-Bond Reactivity: The presence a double carbon-carbon bond in the acrylic part of the molecule allows 3-(3-Furyl)acrylic to undergo addition reactions. It can react with electrophiles in electrophilic addition reactions.It can react with other electrophiles through electrophilic addition. For instance, it can react with bromine (Br2) in a solution, where the double bond breaks, and bromine atoms add across the double bond to form a dibromo - derivative.It can, for example, react with bromine in a solution where the double bonds break and bromine atoms are added across the double bonds to form a dibromo-derivative. This double - bond reactivity also enables it to participate in polymerization reactions.It can also participate in polymerizations due to its double-bond reactivity. Under appropriate conditions, multiple molecules of 3-(3 - Furyl)acrylic acid can react with each other through the double bonds, forming a polymer.Multiple molecules of 3-(3-Furyl)acrylic can react together under the right conditions through their double bonds to form a polymer.
Reactivity of the Furyl Group: The furyl group in 3-(3 - Furyl)acrylic acid also contributes to its chemical reactivity.Reactivity of the Furyl Group. The furyl group also contributes to the chemical reactivity of 3-(3- Furyl)acrylic Acid. The furan ring has a certain degree of aromaticity, which can influence the overall reactivity of the molecule.The furan ring is aromatic to a certain extent, which can affect the overall reactivity. It can participate in reactions such as electrophilic aromatic substitution reactions.It can be involved in reactions like electrophilic aromatic substitute reactions. The electron - rich nature of the furan ring makes it susceptible to attack by electrophiles at specific positions on the ring.The electron-rich nature of the furan rings makes them susceptible to attack by certain electrophiles.
How is 3-(3-Furyl)acrylic acid synthesized?
3-(3 - Furyl)acrylic acid can be synthesized through several methods.Synthesis of 3-(3-Furyl)acrylic acid is possible by several methods. One common approach involves a Knoevenagel condensation reaction.One common method involves a Knoevenagel reaction.
In this reaction, furfural, which contains the furyl group, reacts with malonic acid in the presence of a basic catalyst.Furfural, which has the furyl group in it, reacts with the malonic acid when a basic catalyst is present. The reaction mechanism begins with the deprotonation of malonic acid by the base.The reaction begins with deprotonation by the base of malonic acid. The resulting enolate anion then attacks the carbonyl carbon of furfural.The enolate anion is then attacked by the carbonyl atom of furfural. This forms an intermediate.This forms an intermediary. Subsequently, a series of proton transfers and elimination steps occur.Then, a series proton transfer and elimination steps are performed. The elimination of carbon dioxide from the intermediate leads to the formation of 3-(3 - Furyl)acrylic acid.The intermediate is converted to 3-(3-Furyl)acrylic acid by removing the carbon dioxide.
For example, pyridine can be used as a basic catalyst in this reaction.As an example, pyridine is a good catalyst for this reaction. The reaction is typically carried out in an organic solvent such as ethanol.The reaction is usually carried out in ethanol or another organic solvent. The furfural and malonic acid are dissolved in the solvent, and then the catalyst is added.The catalyst is added after the furfural and the malonic acid have been dissolved in the solvent. The reaction mixture is heated under reflux conditions.The reaction mixture is heated in reflux conditions. The heating helps to drive the reaction forward by increasing the kinetic energy of the reactant molecules, allowing them to overcome the activation energy barrier more easily.The heating increases the kinetic energy in the reactant molecules. This allows them to overcome the activation barrier.
Another possible synthetic route could involve a Wittig reaction.A Wittig reaction is another possible route. First, a phosphonium ylide is prepared from an appropriate phosphonium salt.A phosphonium salt is used to prepare a phosphonium-ylide. The ylide can then react with a furan - containing aldehyde.The ylide is then reacted with a furan-containing aldehyde. The reaction between the ylide and the aldehyde forms a betaine intermediate.The reaction between the aldehyde and the ylide forms a betaine intermediary. This intermediate then undergoes a rearrangement to form an alkene, which in this case is 3-(3 - Furyl)acrylic acid.This intermediate is then rearranged to form an alkene. In this case, it is 3-(3-Furyl)acrylic acid.
The choice of synthesis method depends on various factors.The choice of synthesis method is dependent on a number of factors. The Knoevenagel condensation is relatively straightforward and uses commonly available starting materials.The Knoevenagel condensate is relatively simple and uses readily available starting materials. However, the Wittig reaction can offer more control over the double - bond formation in some cases.In some cases, the Wittig reactions can provide more control over double-bond formation. Additionally, factors such as the cost of starting materials, the ease of purification of the final product, and the reaction conditions (temperature, reaction time, etc.)Other factors include the cost of the starting materials, the ease with which the final product can be purified, and the conditions of the reaction (temperature, time of reaction, etc.). also influence the choice of the synthetic method for the production of 3-(3 - Furyl)acrylic acid.The choice of the synthetic method to produce 3-(3-Furyl)acrylic acid is also influenced by other factors.
What is the stability and shelf life of 3-(3-Furyl)acrylic acid?
3-(3 - Furyl)acrylic acid is a chemical compound with certain stability characteristics.3-(3-Furyl)acrylic acid, a chemical compound that has certain stability properties.
In terms of stability, it is relatively stable under normal conditions when stored properly.When stored correctly, it is relatively stable. However, like many organic compounds, it can be affected by factors such as light, heat, and humidity.Like many organic compounds, however, it can be affected negatively by factors like light, heat, or humidity. Exposure to light, especially ultraviolet light, can potentially cause photochemical reactions.Photochemical reactions can be caused by exposure to light, particularly ultraviolet light. This might lead to degradation or changes in its chemical structure over time.This could lead to a degradation or change in its chemical structure with time. Heat can also accelerate any potential decomposition processes.Heat can also speed up any decomposition process. High temperatures can increase the kinetic energy of the molecules, making them more likely to react with each other or with impurities in the environment.High temperatures can increase kinetic energy in molecules, increasing their likelihood to react with other molecules or impurities. Humidity can be a concern as well.Humidity is also a factor. Moisture in the air can participate in hydrolysis reactions if the compound is susceptible to such processes.If the compound is susceptible, moisture in the air may participate in hydrolysis. If 3-(3 - Furyl)acrylic acid contains functional groups that can react with water, like esters or amides (although it doesn't have these in its basic structure but for the sake of general chemical principles), humidity could lead to breakdown products.If 3-(3-Furyl)acrylic acid has functional groups like esters or amino acids that can react with the water (even though they are not in its basic structure, but for the sake general chemical principles), humidity may lead to breakdown products.
Regarding shelf life, it is difficult to give an exact figure as it depends on storage conditions.It is difficult to give a precise figure for shelf life as it depends on the storage conditions. Under ideal storage conditions, which would typically involve storing the compound in a cool, dry, and dark place, in a well - sealed container, the shelf life can be several months to a year or more.The shelf life of the compound can range from several months to more than a year if it is stored in an ideal environment. This would include storing it in a dark, cool, and dry place in a tightly sealed container. For example, if stored in a refrigerator at around 2 - 8 degrees Celsius, protected from light and with minimal exposure to air and moisture, it can maintain its integrity for an extended period.If, for example, the compound is stored in a refrigerator between 2 and 8 degrees Celsius with minimal exposure to moisture and air, and protected from light, its shelf life can be extended. But if stored at room temperature, say around 20 - 25 degrees Celsius, in an area with significant humidity and exposure to light, the shelf life will likely be shorter, perhaps only a few months.If stored at room temperatures, say 20-25 degrees Celsius, with high humidity and light exposure, the shelf-life will be much shorter, perhaps just a few weeks. Additionally, if the initial purity of the 3-(3 - Furyl)acrylic acid is high, it is more likely to have a longer shelf life as impurities can sometimes act as catalysts for degradation reactions.If the initial purity is high, the 3-(3- Furyl)acrylic acids shelf life will be longer, as impurities may act as catalysts in degradation reactions. Regular quality control checks, such as measuring its purity through techniques like high - performance liquid chromatography (HPLC) or melting point determination, can help in assessing its stability over time and determining when its quality has deteriorated to a point where it is no longer suitable for its intended use.Regular quality checks, like measuring its purity using techniques such as high-performance liquid chromatography or melting point determination can help assess its stability over time.
What are the safety precautions when handling 3-(3-Furyl)acrylic acid?
When handling 3-(3 - Furyl)acrylic acid, several safety precautions should be followed.Safety precautions must be taken when handling 3-(3-Furyl)acrylic Acid.
First, in terms of personal protective equipment.Personal protective equipment is the first thing to consider. Wear appropriate laboratory coats to prevent the chemical from coming into contact with your regular clothing.Wear the appropriate laboratory coats in order to prevent the chemical coming into contact with regular clothing. Lab coats act as a first - line barrier.Lab coats are a first-line barrier. Additionally, use safety goggles to protect your eyes.Use safety goggles as well to protect your eyes. 3-(3 - Furyl)acrylic acid, if it splashes into the eyes, can cause irritation, damage to the cornea, and potential long - term vision problems.If 3-(3- Furyl)acrylic Acid splashes in the eyes, it can cause irritation, corneal damage, and long-term vision problems. Gloves are also essential.Gloves are essential. Chemical - resistant gloves, such as nitrile gloves, should be worn.Gloves that are resistant to chemicals, such as nitrile, should be worn. This helps to avoid skin contact, as the chemical may cause skin irritation, redness, and in some cases, allergic reactions.Wearing gloves that are resistant to chemicals, such as nitrile gloves, will help avoid skin contact.
Second, work in a well - ventilated area.Second, make sure that you are working in an area with good ventilation. If possible, conduct all operations involving 3-(3 - Furyl)acrylic acid in a fume hood.If possible, perform all operations that involve 3-(3-Furyl)acrylic in a fume hood. The fume hood effectively removes any vapors or dust particles that may be released during handling.The fume hood will remove any vapors and dust particles that are released during handling. Inhalation of the chemical can lead to respiratory tract irritation, coughing, and in severe cases, difficulty in breathing.Inhalation can cause irritation of the respiratory tract, coughing and, in severe cases difficulty breathing. A well - ventilated space helps to minimize the concentration of the chemical in the air you breathe.Well-ventilated spaces help to reduce the concentration of the chemical.
Third, be careful during storage.Third, take care when storing. Store 3-(3 - Furyl)acrylic acid in a cool, dry place away from sources of heat and ignition.Store 3-(3-Furyl)acrylic Acid in a cool and dry place, away from heat sources and ignition. It should be kept in a tightly sealed container to prevent evaporation and contamination.Keep it in a tightly-sealed container to prevent contamination and evaporation. Also, keep it away from incompatible substances.Keep it away from other incompatible substances. For example, avoid storing it near strong oxidizing agents or reducing agents, as chemical reactions between them could be violent and potentially dangerous.Avoid storing it near oxidizing or reducing agents. The chemical reactions could be violent.
Fourth, in case of accidental contact.Fourth, in the event of accidental contact. If the chemical gets on the skin, immediately wash the affected area with plenty of soap and water for at least 15 minutes.If the chemical gets onto the skin, wash the area immediately with soap and water. This should be done for at least 15 min. If it splashes into the eyes, rinse the eyes thoroughly with running water for at least 15 minutes, lifting the eyelids occasionally to ensure complete rinsing, and then seek immediate medical attention.If the chemical splashes in the eyes, rinse them thoroughly with running water. Lift the eyelids periodically to ensure that the entire area is rinsing. Seek immediate medical attention if the chemical splashes in the eyes. If inhaled, move to fresh air immediately.If inhaled immediately move to fresh air. If breathing is difficult, provide oxygen and call for medical help.If breathing is difficult provide oxygen and contact medical help. In case of ingestion, do not induce vomiting unless directed by medical personnel, and seek emergency medical treatment right away.In the event of ingestion, you should not induce vomiting without medical supervision. Seek immediate medical attention.
Finally, when disposing of 3-(3 - Furyl)acrylic acid, follow all local environmental regulations.Follow all local environmental regulations when disposing 3-(3-Furyl)acrylic acid. Do not pour it down the drain or discard it in regular trash.Do not pour the acid down the drain, or throw it away in regular trash. It may need to be disposed of through a proper chemical waste disposal system to prevent environmental pollution.It may be necessary to dispose of it through a proper system for disposing chemical waste to prevent pollution.