What is the chemical structure of 3-(3-Pyridyl)acrylic acid?

3-(3-Pyridyl)acrylic acid is an organic compound with an interesting chemical structure.3-(3-Pyridylacrylic acid) is an organic compound that has an interesting chemical structure.
Let's break down its structure description.Let's describe its structure. First, the term "acrylic acid" gives us a basic framework.The term "acrylic" provides a framework for understanding the chemical. Acrylic acid has a structure where there is a two - carbon chain with a double bond between the two carbons (a vinyl group) and a carboxyl group (-COOH) attached to one of the carbons.Acrylic acid is a two-carbon chain with a double-bond between the two carbons. (A vinyl group). A carboxyl group (+COOH) is attached to one carbon. The general formula for acrylic acid is CH2=CH - COOH.The general formula of acrylic acid is CH2=CH-COOH.

Now, when we consider the "3-(3 - Pyridyl)" part.When we look at the "3-(3-Pyridyl)", it is a bit more complicated. The pyridyl group is a derivative of the pyridine ring.The pyridyl ring is a derivative. Pyridine is a six - membered aromatic heterocyclic compound with one nitrogen atom in the ring.The pyridine ring is six-membered heterocyclic aromatic compound with one nitrogen in it. In the 3 - position of the pyridine ring, it is attached to the acrylic acid part.In the 3 – position of the pyridine, it is attached with the acrylic acid part. So, in 3-(3 - Pyridyl)acrylic acid, the 3 - position of the pyridine ring is connected to the carbon of the vinyl group in acrylic acid.In 3-(3- Pyridyl-)acrylic acid the 3 - position pyridine ring connects to the carbon group of the acrylic acid.

The pyridine ring in 3-(3 - Pyridyl)acrylic acid has a planar structure due to the delocalization of p - electrons, which is a characteristic of aromatic compounds.The pyridine ring of 3-(3- Pyridyl-acrylic acid) has a planar shape due to delocalization of the p-electrons, which is characteristic of aromatic compounds. The nitrogen atom in the pyridine ring has a lone pair of electrons, which can participate in various chemical reactions such as hydrogen bonding or acting as a base in some cases.The nitrogen atom of the pyridine has a single pair of electrons that can be used in various chemical reactions, such as hydrogen bonds or acting as a basic in some cases.

The double bond in the acrylic acid part of 3-(3 - Pyridyl)acrylic acid is reactive.The double bond in 3-(3-Pyridyl)acrylic acids is reactive. It can undergo addition reactions, for example, addition of halogens, hydrogen, or other electrophiles.It can undergo addition reactions such as the addition of halogens or hydrogen. The carboxyl group (-COOH) at the end of the acrylic acid part is also reactive.The carboxyl group at the end (-COOH), which is part of the acrylic acid, is also reactive. It can participate in acid - base reactions, forming salts with bases.It can be used in acid-base reactions to form salts. It can also react with alcohols to form esters in the presence of an appropriate catalyst, such as sulfuric acid in a Fischer esterification reaction.It can also form esters when it reacts with alcohols in the presence an appropriate catalyst such as sulfuric in a Fischer esterification.

Overall, the combination of the pyridine ring, the double bond in the vinyl part, and the carboxyl group in 3-(3 - Pyridyl)acrylic acid gives the compound a rich chemistry and potential applications in various fields such as pharmaceuticals, materials science, and organic synthesis.The combination of the pyridine group, the double bond on the vinyl part and the carboxyl groups in 3-(3-Pyridyl)acrylic acids gives the compound an interesting chemistry. It has potential applications in many fields, such as pharmaceuticals and materials science.

What are the applications of 3-(3-Pyridyl)acrylic acid?

3-(3-Pyridyl)acrylic acid is a compound with various applications in different fields.3-(3-Pyridylacrylic) acid is a compound that has many applications in various fields.
In the pharmaceutical industry, it serves as an important intermediate for the synthesis of numerous drugs.It is an important intermediate in the pharmaceutical industry for the synthesis and synthesis of many drugs. Its pyridine and acrylic acid moieties can participate in chemical reactions to form complex structures with potential biological activities.Its pyridine- and acrylic acid-containing moieties can be involved in chemical reactions that form complex structures with biological activity potential. For example, it can be used to create molecules that target specific biological pathways.It can be used, for example, to create molecules that target certain biological pathways. Compounds derived from 3-(3 -Pyridyl)acrylic acid might have antibacterial, anti - inflammatory, or anti - cancer properties.Compounds derived by 3-(3-Pyridyl-acrylic) acid may have antibacterial, cancer-fighting, anti-inflammatory, or anti-inflammatory properties. By modifying the structure through further chemical reactions, researchers can fine - tune the biological activity of the resulting drugs to treat various diseases.Researchers can fine-tune the biological activity of drugs by modifying the structure via further chemical reactions.

In the field of materials science, 3-(3 -Pyridyl)acrylic acid can be used in the preparation of functional polymers.In the field of material science, 3-(3-Pyridyl )acrylic acid is used to prepare functional polymers. When incorporated into a polymer matrix, it can introduce unique properties.It can be incorporated into polymer matrices to introduce unique properties. The pyridine group has the ability to coordinate with metal ions.The pyridine group can coordinate with metal ions. This property can be exploited to create polymers that can selectively bind to metal ions, which is useful in applications such as metal ion separation and sensing.This property can be used to create polymers which can selectively bind metal ions. This is useful for applications such as metal-ion separation and sensoring. Additionally, the unsaturated double bond in the acrylic acid part allows for polymerization reactions.The unsaturated double bonds in the acrylic acid allow for polymerization reactions. These polymers can be used in coatings, where they can provide enhanced adhesion, durability, and chemical resistance.These polymers are used in coatings to provide increased adhesion, durability and chemical resistance.

In the area of organic synthesis, 3-(3 -Pyridyl)acrylic acid is a valuable building block.In the field of organic synthesis 3-(3-Pyridyl )acrylic acid is an important building block. It can undergo a variety of reactions such as Michael addition, Diels - Alder reactions, and Heck reactions.It can undergo various reactions, such as Michael additions, Diels-Alder reactions, or Heck reactions. These reactions enable the construction of more complex organic molecules with diverse structures.These reactions allow the construction of complex organic molecules that have diverse structures. Organic chemists can use it to create compounds with specific geometries and functional groups, which are essential for the development of new materials, agrochemicals, and other organic products.Organic chemists use it to create compounds that have specific geometries or functional groups. These compounds are important for the development of new organic products, agrochemicals and other materials.

In summary, 3-(3 -Pyridyl)acrylic acid plays a crucial role in pharmaceuticals, materials science, and organic synthesis.Summary: 3-(3-Pyridyl )acrylic acid is a key component in organic synthesis, materials science and pharmaceuticals. Its unique structure allows for a wide range of chemical modifications and applications, making it an important compound in modern chemical research and industry.Its unique structure makes it a compound of great importance in modern chemical research.

What are the physical and chemical properties of 3-(3-Pyridyl)acrylic acid?

3-(3-Pyridyl)acrylic acid is an organic compound with certain characteristic physical and chemical properties.3-(3-Pyridylacrylic acid) is a compound that has certain physical and chemical characteristics.
Physical Properties

Appearance: It typically exists as a solid.Appearance: Usually, it is a solid. Solids of this compound often have a crystalline or powder - like form.Solids of the compound are often crystalline or powder-like. The color can range from white to off - white, which is common for many organic acids with relatively simple structures.The color can vary from white to off-white, which is common among many organic acids that have relatively simple structures.

Melting Point: The melting point of 3-(3 - Pyridyl)acrylic acid is an important physical property.Melting Point: The melting temperature of 3-(3-pyridyl)acrylic is an important property. It melts at a specific temperature, which is determined by the strength of the intermolecular forces within the solid.It melts only at a certain temperature, which is determined based on the strength of intermolecular forces in the solid. The intermolecular forces, such as hydrogen bonding, van der Waals forces, and dipole - dipole interactions, hold the molecules together in the solid state.The molecules are held together by intermolecular forces such as hydrogen bonds, van der Waals and dipole-dipole interactions. When heated to its melting point, these forces are overcome, and the solid transforms into a liquid.These forces are overcome when the solid is heated to its melting temperature.

Solubility: In terms of solubility, it shows some solubility in polar solvents.Solubility: It shows some solubility with polar solvents. Water, being a highly polar solvent, can dissolve a certain amount of 3-(3 - Pyridyl)acrylic acid due to the presence of the carboxylic acid group (-COOH).Water, a highly-polar solvent, can dissolve some 3-(3-pyridyl)acrylic acids due to the presence carboxylic acid group. The carboxylic acid group can form hydrogen bonds with water molecules.The carboxylic group can form hydrogen bond with water molecules. However, its solubility in water is not extremely high because the pyridyl group also contributes to the hydrophobic nature of the molecule.Its solubility in the water is not very high, however, because the pyridyl groups also contribute to the hydrophobicity of the molecule. It is more soluble in organic solvents like ethanol and methanol.It is more soluble when it comes to organic solvents such as ethanol and methanol. These alcohols can form hydrogen bonds with the carboxylic acid group and also have some compatibility with the pyridyl ring due to their relatively non - polar alkyl parts.These alcohols are able to form hydrogen bonds with carboxylic acids and have some compatibility with pyridyl rings due to their non-polar alkyl parts.

Chemical Properties

Acidity: The carboxylic acid group in 3-(3 - Pyridyl)acrylic acid gives it acidic properties.Acidity: The carboxylic group in 3-(3-pyridyl)acrylic gives it acidic characteristics. It can donate a proton (H+) in an aqueous solution or in the presence of a base.It can donate a proton (H+) when in an aqueous or base-containing solution. This acidic behavior is a characteristic of carboxylic acids.This acidic behavior of carboxylic acid is a characteristic. The acidity constant (pKa) of the carboxylic acid group in this compound is related to the stability of the resulting carboxylate anion after the loss of a proton.The acidity constant of the carboxylic group in this compound (pKa), is related to the stability after proton loss of the carboxylate anion. The presence of the pyridyl group can influence the pKa value.The presence of pyridyl groups can affect the pKa values. The electron - withdrawing or - donating effects of the pyridyl ring can either stabilize or destabilize the carboxylate anion, thus affecting the acidity of the carboxylic acid group.The electron-donating or - withdrawing effects of the pyridyl group can either stabilize or destroy the carboxylate anion. This will affect the acidity of carboxylic acid groups.

Reactivity of the Double Bond: The compound contains a carbon - carbon double bond (C = C) in the acrylic acid part.Reactivity of the Double Bond. The compound contains in the acrylic acid a double carbon-carbon bond (C=C). This double bond is reactive and can undergo addition reactions.This double bond can undergo addition reactions. For example, it can react with halogens (such as bromine) in an addition reaction, where the bromine atoms add across the double bond, breaking the p - bond of the double bond and forming new carbon - bromine single bonds.It can, for example, react with halogens, such as bromine, in an addition reaction where the bromine adds across the double bonds, breaking the p-bond of the double bonds and forming new single carbon-bromine bonds. It can also react with hydrogen in the presence of a catalyst (hydrogenation reaction) to convert the double bond into a single bond, forming a saturated compound.It can also be used to react with hydrogen (hydrogenation reaction), in the presence a catalyst, to convert the double bonds into single bonds.

Reactivity of the Pyridyl Ring: The pyridyl ring, a heterocyclic aromatic structure, can also participate in various chemical reactions.Reactivity of Pyridyl Ring. The pyridyl structure, which is a heterocyclic aroma, can participate in a variety of chemical reactions. It can undergo electrophilic aromatic substitution reactions.It can undergo electrophilic substitution reactions. Due to the presence of the nitrogen atom in the ring, the electron density distribution in the pyridyl ring is different from that of a benzene ring.The pyridyl rings electron density distribution is different than that of a typical benzene ring due to the presence in the ring of a nitrogen atom. The nitrogen atom can direct the incoming electrophile to specific positions on the ring.The nitrogen atom can direct an incoming electrophile towards specific positions on a ring. For example, nitration or halogenation reactions can occur on the pyridyl ring under appropriate reaction conditions.Under the right conditions, nitration and halogenation can occur on pyridyl rings. Additionally, the pyridyl nitrogen can act as a Lewis base, coordinating with metal ions or reacting with electrophiles to form various derivatives.The pyridyl ring can also act as a Lewis basis, coordinating metal ions and reacting with electronphiles to produce various derivatives.

How is 3-(3-Pyridyl)acrylic acid synthesized?

3-(3 - Pyridyl)acrylic acid can be synthesized through the following general steps.The following general steps can be used to synthesize 3-(3-Pyridyl)acrylic Acid.
1. Knoevenagel condensation method
This is a common approach.This is a common method. Start with 3 - pyridinecarboxaldehyde and malonic acid as the key starting materials. These two compounds are reacted in the presence of a base catalyst.These two compounds are then reacted with a base catalyst. A typical base used could be piperidine.Piperidine is a common base. The reaction is usually carried out in a suitable solvent, such as pyridine.The reaction is carried out in a suitable solvant, such as pyridine.
The role of the base is to deprotonate malonic acid, generating a carbanion.The base's role is to deprotonate the malonic acid and generate a carbanion. This carbanion then attacks the carbonyl carbon of 3 - pyridinecarboxaldehyde. Subsequently, a series of elimination and rearrangement steps occur.Then, a series elimination and rearrangement reactions occur. The elimination of a molecule of carbon dioxide from the intermediate formed leads to the formation of 3-(3 - Pyridyl)acrylic acid.The formation of 3-(3-Pyridyl)acrylic Acid is achieved by removing a carbon dioxide molecule from the intermediate.
The reaction temperature is often carefully controlled, typically in the range of 80 - 120 degC.The temperature of the reaction is usually carefully controlled and typically falls between 80-120 degC. The reaction time can vary depending on the reaction scale and the efficiency of the reaction system, usually several hours to ensure sufficient conversion.The reaction time will vary depending on the scale of the reaction and the efficiency level of the system. It is usually several hours in order to ensure sufficient conversion. After the reaction is complete, the reaction mixture is cooled.The reaction mixture is cooled after the reaction has been completed. The product can be isolated through methods like acid - base extraction.Acid-base extraction is one way to isolate the product. First, the reaction mixture is acidified to protonate the product if it exists in its anionic form due to the basic reaction conditions.The reaction mixture is first acidified in order to protonate any product that may exist as an anionic form because of the basic reaction conditions. Then, it can be extracted into an organic solvent such as ethyl acetate.It can then be extracted in an organic solvent, such as ethyl-acetate. The organic layer is then washed, dried over anhydrous salts like magnesium sulfate, and the solvent is removed under reduced pressure to obtain the crude product.The organic layer is washed and dried over anhydrous sodium salts such as magnesium sulfate. The solvent is then removed under reduced pressure in order to obtain the crude product. The crude product can be further purified by recrystallization from a suitable solvent system, for example, a mixture of ethanol and water, to obtain pure 3-(3 - Pyridyl)acrylic acid.The crude product may be purified further by recrystallization using a suitable solvent, such as a mixture of water and ethanol, to obtain pure 3-(3-Pyridyl)acrylic Acid.

2. Other possible methodsOther possible methods
Another potential route could involve the functionalization of a pre - existing pyridine derivative with an acrylic acid - like moiety.Another possible route would be to functionalize a pyridine derivative that already exists with an acrylic acid-like moiety. For instance, if there is a pyridine compound with a suitable leaving group at the 3 - position, it could react with an acrylic acid derivative containing a nucleophilic group.If there is a pyridine derivative with a suitable nucleophilic group in the 3 - position it could react with a nucleophilic acrylic acid derivative. However, this method may require more elaborate synthetic steps to prepare the starting materials with the appropriate functional groups.This method may require more complex synthetic steps to prepare starting materials with functional groups. Also, controlling the regioselectivity of the reaction to ensure the attachment at the 3 - position of the pyridine ring can be a challenge.Controlling the regioselectivity to ensure attachment at the 3-position of the pyridine rings can also be a challenge. Compared to the Knoevenagel condensation method, this alternative route may be less straightforward and more complex in terms of reaction design and execution.This alternative method may be more complex and less straightforward than the Knoevenagel condensing method in terms of design and execution. Overall, the Knoevenagel condensation is a more commonly employed and practical approach for the synthesis of 3-(3 - Pyridyl)acrylic acid.Knoevenagel condensation has been found to be a more practical and common method for the synthesis 3-(3-Pyridyl)acrylic Acid.

What are the safety precautions when handling 3-(3-Pyridyl)acrylic acid?

3-(3 - Pyridyl)acrylic acid is a chemical compound that requires certain safety precautions during handling.3-(3-Pyridyl)acrylic Acid is a chemical compound which requires certain safety precautions when handling.
First, in terms of personal protective equipment.Personal protective equipment is the first thing to consider. Wear appropriate respiratory protection.Wear respiratory protection. If there is a risk of dust or vapor generation, a respirator with a suitable filter should be used to prevent inhalation of the chemical.To prevent inhalation, use a respirator equipped with a filter if there is a possibility of dust or vapor. This is crucial as inhaling 3-(3 - Pyridyl)acrylic acid can potentially cause irritation to the respiratory tract, and in more severe cases, may have long - term health impacts.Inhaling 3-(3-Pyridyl-)acrylic acid may cause irritation of the respiratory tract and, in more severe cases can have long-term health effects.

For eye protection, safety goggles or a face shield should be worn.Safety goggles or face shields should be worn for eye protection. Chemical splashes can occur during handling, and getting this compound in the eyes can lead to significant irritation, pain, and possible damage to the eye tissues.During handling, chemical splashes may occur. Getting this compound into the eyes can cause significant irritation, pain and even damage to the eye tissue.

Regarding hand protection, thick - walled chemical - resistant gloves are necessary.Hand protection is best achieved by using gloves with thick walls that are chemical resistant. Skin contact with 3-(3 - Pyridyl)acrylic acid can result in skin irritation, itching, and redness.Skin irritation, itching and redness can occur when 3-(3- Pyridyl )acrylic acid is in contact with the skin. Prolonged or repeated contact might even cause more serious skin problems.Contact that is prolonged or repeated can cause skin problems.

In the handling environment, ensure good ventilation.Assure good ventilation in the handling environment. This helps to quickly disperse any fumes or dust that may be generated during the handling process.This will help to disperse any dust or fumes that may be produced during the handling process. A well - ventilated area reduces the concentration of the chemical in the air, thus minimizing the risk of inhalation.A well-ventilated area reduces the concentration in the air of the chemical, reducing the risk of inhalation.

When storing 3-(3 - Pyridyl)acrylic acid, keep it in a cool, dry place away from sources of heat and ignition.Store 3-(3-Pyridyl)acrylic Acid in a cool and dry place, away from heat sources and ignition. This compound may have certain chemical reactivity, and exposure to high temperatures or flames could potentially lead to decomposition or even combustion in some cases.This compound has a certain chemical reactivity. Exposure to high temperatures or fires can lead to decomposition, or even combustion.

In case of accidental contact, if it gets on the skin, immediately wash the affected area with plenty of soap and water for at least 15 minutes.If it accidentally gets on your skin, wash the area thoroughly with soap and water. Do this for at least 15 mins. If it enters the eyes, flush the eyes with copious amounts of water for an extended period and seek immediate medical attention.If it gets into the eyes, wash them with a lot of water and for a long time. Seek immediate medical attention. In case of inhalation, move to an area with fresh air and if breathing difficulties persist, call for emergency medical help.If you inhale the substance, get to a place with fresh air. If breathing problems persist, seek emergency medical attention.

During disposal, follow all local and national regulations.Follow all local and national regulations when disposing of the product. Do not simply discard 3-(3 - Pyridyl)acrylic acid in regular waste.Do not throw away 3-(3-Pyridyl)acrylic in regular waste. It should be disposed of in an appropriate waste stream for chemical compounds to prevent environmental contamination.It should be disposed in a waste stream that is appropriate for chemical compounds. This will prevent contamination of the environment.