What is the chemical structure of 3-(4-Bromo-2-fluoro-phenyl)-acrylic acid?

The chemical structure of 3-(4 - Bromo - 2 - fluoro - phenyl)acrylic acid can be understood by breaking it down into its components.By breaking down the chemical structure of 3-(4- Bromo-2- Fluoro-phenyl)acrylic Acid, you can understand its composition.
First, let's consider the phenyl group.Let's start with the phenyl ring. A phenyl group is a six - membered aromatic ring, C6H5.A phenyl ring is a six-membered aromatic ring C6H5. In this compound, the phenyl ring has two substituents.The phenyl group has two substituents in this compound. At the 4 - position (counting from a chosen reference carbon on the ring), there is a bromine atom (Br), and at the 2 - position, there is a fluorine atom (F).The bromine atom is at the 4 -position (counting backwards from a reference carbon chosen on the ring) and the fluorine is at the 2 – position. So the part of the structure related to the substituted phenyl ring is a benzene ring with a Br attached to one carbon and an F attached to another carbon in the specific 4 - and 2 - positions respectively.The part of the structure that is related to the substituted Phenyl Ring is a benzene with a Br attached on one carbon, and an F attached on another carbon at the specific 4'and 2'positions.

Next, we have the acrylic acid part.The next step is the acrylic acid. Acrylic acid has the general formula CH2=CH - COOH.Acrylic acid is a general formula CH2=CH-COOH. It consists of a vinyl group (CH2=CH -) attached to a carboxylic acid group (-COOH).It is composed of a vinyl group attached to a carboxylic group (-COOH).

In 3-(4 - Bromo - 2 - fluoro - phenyl)acrylic acid, the 3 - position of the acrylic acid moiety is where the 4 - bromo - 2 - fluoro - phenyl group is attached.The 4 – bromo- 2– fluoro- phenyl group of 3-(4- Bromo- 2– fluoro- phenyl- phenyl-acrylic acid) is attached to the moiety at the 3 position. So the overall structure can be thought of as follows: the 4 - bromo - 2 - fluoro - phenyl group is connected to the carbon atom of the vinyl part of the acrylic acid.The overall structure is as follows: the 4-bromo-2-fluoro-phenyl group connects to the carbon atom in the vinyl part of acrylic acid. The carbon - carbon double bond of the vinyl group is still present, and on the other end of the vinyl group is the carboxylic acid functional group.The double carbon-carbon bond of the vinyl is still present. On the other end is the carboxylic group.

To summarize, the molecule contains a benzene ring with a bromine at the 4 - position and a fluorine at the 2 - position, which is then linked to a carbon atom of a vinyl group.The molecule is composed of a benzene group with a bromine atom at the 4 position and a 2 position fluorine atom, which are then linked to the carbon atoms of a vinyl ring. The vinyl group is further connected to a carboxylic acid group.The vinyl group is connected to a carboxylic group. This arrangement gives the compound its unique chemical and physical properties, which can be relevant in various chemical reactions, such as those in organic synthesis, and potentially in biological applications depending on its reactivity with biological molecules.This arrangement gives the compound unique chemical and physical characteristics, which can be important in various chemical reactions such as those in organic syntheses, and possibly in biological applications, depending on its reactivity to biological molecules. The presence of the halogen atoms (bromine and fluorine) can influence the molecule's polarity, reactivity in substitution reactions, and its interaction with other substances.The presence of halogen (bromine and Fluorine) atoms can affect the molecule's polarity and reactivity during substitution reactions as well as its interaction with other substances. The carboxylic acid group allows for reactions like esterification and salt formation, which are important in the synthesis of more complex organic compounds.The carboxylic group allows for reactions such as esterification and the formation of salts, which are crucial in the synthesis more complex organic compounds.

What are the applications of 3-(4-Bromo-2-fluoro-phenyl)-acrylic acid?

3-(4-Bromo-2-fluoro-phenyl)acrylic acid is an organic compound with several potential applications.
In the field of medicinal chemistry, it can serve as a crucial building block.It can be used as a building block in the field of medicinal chemical. The presence of the bromine and fluorine atoms in its structure provides unique reactivity and properties.Its unique properties and reactivity are due to the presence of bromine and fluorine in its structure. These halogen atoms can influence the compound's lipophilicity and electronic characteristics, which are important factors in drug - receptor interactions.These halogens can affect the compound's electronic and lipophilicity characteristics, which are key factors in drug-receptor interactions. It can be incorporated into drug molecules to enhance their binding affinity to specific biological targets.It can be added to drug molecules to increase their affinity for binding to specific biological targets. For example, it might be used in the synthesis of anti - inflammatory drugs.It could be used to synthesize anti-inflammatory drugs, for example. By attaching this moiety to a lead compound, researchers can potentially improve the drug's ability to penetrate cell membranes and interact with relevant enzymes or receptors involved in the inflammatory pathways.Researchers can improve the drug's penetration of cell membranes by attaching this moiety.

In materials science, 3-(4 - Bromo - 2 - fluoro - phenyl)acrylic acid can be utilized in the preparation of functional polymers.In materials science, 3-(4-bromo- 2-fluoro-phenyl-phenyl-acrylic acid) can be used to prepare functional polymers. It can participate in polymerization reactions, either through its acrylic acid group.It can participate in polymerization through its acrylic acid group. The resulting polymers can have special optical or electronic properties due to the presence of the bromine and fluorine - containing aromatic ring.The presence of the aromatic ring containing bromine and fluorine can give the polymers special optical or electronic properties. For instance, these polymers could be used in the production of organic light - emitting diodes (OLEDs).These polymers can be used to produce organic light-emitting diodes. The bromine and fluorine atoms can tune the energy levels of the polymer, affecting its fluorescence efficiency and color emission.The fluorine and bromine atoms can be used to tune the energy level of the polymer. This will affect its fluorescence efficiency. This can lead to the development of OLEDs with improved performance and color purity.This can lead to OLEDs that have improved performance and color purity.

In the area of agrochemicals, it may have applications in the synthesis of pesticides or herbicides.It may be used in the synthesis or pesticides and herbicides. The unique structure of the compound can be designed to target specific biological processes in pests or weeds.The unique structure of this compound can be tailored to target specific biological processes within pests or weeds. The bromine and fluorine substituents can help the molecule interact selectively with the proteins or enzymes in these organisms, disrupting their normal physiological functions.The fluorine and bromine substituents help the molecule to interact selectively with proteins or enzymes of these organisms disrupting their normal physiological function. This selectivity can lead to more effective and environmentally friendly agrochemicals that are less harmful to non - target organisms.This selectivity can result in more environmentally friendly and effective agrochemicals, which are less harmful to non-target organisms.

In chemical research, 3-(4 - Bromo - 2 - fluoro - phenyl)acrylic acid is a valuable reagent for organic synthesis.In organic synthesis, 3-(4-Bromo- 2-Fluoro- Phenyl)acrylic Acid is a valuable reagent. It can be used in various reactions such as coupling reactions.It can be used for various reactions, such as coupling. The bromine atom can participate in cross - coupling reactions like Suzuki - Miyaura or Stille reactions, allowing for the formation of new carbon - carbon bonds.The bromine atom is able to participate in cross-coupling reactions such as Suzuki - Miyaura and Stille reactions. This allows for the formation of carbon-carbon bonds. This enables the synthesis of more complex organic molecules with diverse structures, which can be further explored for different applications in the future.This allows the synthesis of complex organic molecules that have diverse structures. These can be explored further for future applications.

What are the properties of 3-(4-Bromo-2-fluoro-phenyl)-acrylic acid?

3-(4 - Bromo - 2 - fluoro - phenyl)acrylic acid is an organic compound with several notable properties.3-(4-bromo-2-fluoro-phenyl-phenyl-acrylic acid) is a compound with a number of notable properties.
Physical properties

In terms of appearance, it is likely to be a solid at room temperature.It is likely that it will appear as a solid when at room temperature. Many aromatic carboxylic acids, which this compound belongs to, are solids due to the relatively strong intermolecular forces present.Due to the relatively strong intermolecular force, many aromatic carboxylic acid compounds, including this compound, are solids. The presence of the bromine, fluorine, and carboxylic acid functional groups contribute to its polarity.Its polarity is due to the presence of carboxylic acid, bromine and fluorine functional groups. The bromine atom, being large and electronegative, and the fluorine atom, which is highly electronegative, along with the polar -COOH group, make the molecule polar.The polarity of the molecule is due to the large and highly electronegative bromine atom and the highly electronegative fluorine atom. This polarity affects its solubility properties.This polarity influences its solubility. It is likely to be sparingly soluble in non - polar solvents such as hexane.It is unlikely to be soluble in non-polar solvents like hexane. However, it may show some solubility in polar organic solvents like ethanol or acetone.It may be soluble in polar organic solvents such as ethanol or Acetone. In water, its solubility might be limited because although the carboxylic acid group can form hydrogen bonds with water, the relatively large non - polar aromatic part of the molecule reduces its overall solubility in water.In water, it's solubility may be limited, because the carboxylic group can form hydrogen bond with water. However, the relatively large non-polar aromatic part of molecule reduces the overall solubility.

Chemical properties

The carboxylic acid group (-COOH) in 3-(4 - Bromo - 2 - fluoro - phenyl)acrylic acid is reactive.The carboxylic group (-COOH), in 3-(4-Bromo-2-fluoro-phenyl)acrylic acids, is reactive. It can undergo typical carboxylic acid reactions.It can undergo carboxylic acid reactions. For example, it can react with bases to form salts.It can, for example, react with bases to produce salts. When treated with an alkali like sodium hydroxide (NaOH), it will form the corresponding carboxylate salt, 3-(4 - Bromo - 2 - fluoro - phenyl)acrylate, and water.When treated with an acid like sodium hydroxide, it will form the carboxylate salt, 3-(4-Bromo-2-fluoro-phenyl)acrylate and water. This reaction is an acid - base neutralization reaction.This is an acid-base neutralization reaction. The carboxylic acid can also be esterified.The carboxylic acids can also be esterified. When reacted with an alcohol in the presence of an acid catalyst, such as sulfuric acid, it forms an ester.It forms an ester when it reacts with an alcohol, in the presence an acid catalyst such as sulfuric. This reaction is important in organic synthesis for the formation of various esters which have applications in the fragrance and flavor industry.This reaction is crucial in organic synthesis because it forms various esters that are used in the fragrance and flavor industries.

The double bond in the acrylic acid part of the molecule is also a site of reactivity.The double bond of the acrylic acid molecule is a reactivity site. It can participate in addition reactions.It can be involved in addition reactions. For instance, it can react with bromine (Br2) in an electrophilic addition reaction.It can, for example, react with bromine in an electrophilic reaction. The bromine adds across the double bond, forming a dibromo - derivative.Bromine adds across double bond to form a dibromo-derivative. This double bond can also be used in polymerization reactions.This double bond is also useful in polymerization reactions. Under appropriate conditions, monomers containing such double bonds can polymerize to form polymers, which can have applications in the production of plastics and other polymeric materials.Monomers containing these double bonds can polymerize under the right conditions to form polymers that can be used in the production and use of plastics, polymers, and other polymeric materials.

The halogen atoms, bromine and fluorine, on the phenyl ring also influence the reactivity of the compound.The halogen atoms on the phenyl rings, bromine and Fluorine, also influence the reactivity. The bromine atom can be involved in substitution reactions.Bromine can be involved in substitute reactions. Nucleophilic substitution reactions can occur where a nucleophile replaces the bromine atom under suitable reaction conditions.Under certain conditions, nucleophilic reactions can occur when a nucleophile is used to replace the bromine atom. The fluorine atom, due to its high electronegativity, can affect the electron density of the phenyl ring, influencing the reactivity of the entire molecule in electrophilic aromatic substitution reactions.Fluorine, because of its high electronegativity can influence the electron density of phenyl rings, affecting the reactivity in electrophilic aromatic substitute reactions. Overall, 3-(4 - Bromo - 2 - fluoro - phenyl)acrylic acid has a combination of physical and chemical properties that make it a useful compound in organic synthesis and potentially in various industrial applications.Overall, 3-(4-Bromo- 2-Fluoro-phenyl-acrylic acid) has a combination physical and chemical properties which make it useful in organic synthesis.

What is the synthesis method of 3-(4-Bromo-2-fluoro-phenyl)-acrylic acid?

Here is a possible synthesis method of 3-(4 - Bromo - 2 - fluoro - phenyl)acrylic acid:Here is a possible method of synthesis of 3-(4-Bromo-2-Fluoro-Phenyl)acrylic Acid:
1. Preparation of the starting materialPrepare the starting material
The synthesis often starts with 4 - bromo - 2 - fluorobenzaldehyde.The synthesis is usually started with 4 -bromo -2 -fluorobenzaldehyde. This compound can be obtained through a series of reactions from appropriate benzene derivatives.This compound can be produced by a series reactions using appropriate benzene derivates. For example, starting from 4 - bromo - 2 - fluorotoluene.Starting with 4 - Bromo -2 - Fluorotoluene, for example. Oxidation of 4 - bromo - 2 - fluorotoluene using an appropriate oxidizing agent such as potassium permanganate or chromium - based oxidants in an acidic medium can convert the methyl group to an aldehyde group, yielding 4 - bromo - 2 - fluorobenzaldehyde.The methyl group can be converted to an aldehyde by oxidizing 4 – bromo 2 – fluorotoluene with potassium permanganate, chromium-based oxidants or other appropriate oxidizing agents in an acidic environment.

2. Knoevenagel condensation
The key step in synthesizing 3-(4 - Bromo - 2 - fluoro - phenyl)acrylic acid is the Knoevenagel condensation reaction.The Knoevenagel reaction is the key step to synthesizing 3-(4-Bromo- 2 – Fluoro- Phenyl)acrylic Acid. In this reaction, 4 - bromo - 2 - fluorobenzaldehyde reacts with a compound containing an active methylene group.In this reaction, the 4 - Bromo -2 - Fluorobenzaldehyde is combined with a compound that contains an active methylene. Malonic acid is a commonly used reagent in this context.In this context, malonic acid is commonly used.
The reaction is typically carried out in the presence of a base catalyst.The reaction is usually carried out in presence of a catalyst. Piperidine is a frequently used base for this type of reaction.Piperidine is often used as a base in this type of reaction. The reaction mixture is usually heated in an appropriate solvent.The reaction mixture is heated in a suitable solvent. Solvents like pyridine or ethanol can be used.Solvents such as pyridine or alcohol can be used.
During the reaction, the base deprotonates the active methylene group of malonic acid, generating a carbanion.This carbanion then attacks the carbonyl carbon of 4 - bromo - 2 - fluorobenzaldehyde. This carbanion then attacks the carbonyl carbon of 4 - bromo - 2 - fluorobenzaldehyde.Sui Hou , a series of proton - transfer and elimination reactions occur. The intermediate formed loses a molecule of carbon dioxide, resulting in the formation of 3-(4 - Bromo - 2 - fluoro - phenyl)acrylic acid.The intermediate forms loses one molecule of carbon, resulting in 3-(4-Bromo -2 - Fluoro phenyl )acrylic acid.

3. Purification
After the reaction is complete, the product needs to be purified.Purification is required after the reaction has been completed. One common purification method is recrystallization.Recrystallization is a common method of purification. The crude product is dissolved in a suitable solvent system.The crude product is dissolved into a suitable solvent. Solvents such as a mixture of ethanol and water can be used.Solvents like ethanol and water mixtures can be used. As the solution cools, pure 3-(4 - Bromo - 2 - fluoro - phenyl)acrylic acid crystallizes out, while impurities remain in the solution.As the solution cools down, the pure 3-(4-Bromo- 2 – Fluoro- phenyl-acrylic acid) crystallizes while the impurities remain. Filtration can then be used to isolate the pure solid product.Filtration is used to isolate the pure solid. Another purification method could be column chromatography, where the crude product is separated on a silica gel column using an appropriate eluent system to obtain the pure 3-(4 - Bromo - 2 - fluoro - phenyl)acrylic acid.Column chromatography is another purification method. The crude product can be separated on a silica-gel column using a suitable eluent to obtain pure 3-(4-Bromo- 2 – Fluoro- phenyl-acrylic acid).

What are the safety precautions for handling 3-(4-Bromo-2-fluoro-phenyl)-acrylic acid?

3-(4 - Bromo - 2 - fluoro - phenyl)acrylic acid is a chemical compound, and when handling it, several safety precautions should be taken.When handling 3-(4- Bromo- 2- Fluoro- Phenyl)acrylic Acid, it is important to take several safety precautions.
First, in terms of personal protective equipment.Personal protective equipment is the first thing to consider. Wear appropriate respiratory protection.Wear respiratory protection. Since it's possible that fine particles or vapors of this chemical could be present in the air during handling, a properly - fitted respirator with an appropriate filter for organic chemicals can prevent inhalation of potentially harmful substances.A respirator fitted with a filter that is suitable for organic chemicals will prevent inhalation. This helps to avoid respiratory tract irritation, which could range from mild coughing to more severe damage in the long - term.This can help to prevent respiratory tract irritation which could range from mild symptoms such as coughing, to more serious long-term damage.

For eye protection, safety goggles should be worn at all times during handling.Safety goggles are recommended to be worn at all time when handling chemicals. Chemical splashes into the eyes can cause serious damage, including burns, irritation, and potential loss of vision.Chemical splashes in the eyes can cause serious injury, including irritation, burns, and even loss of vision. The goggles should form a tight seal around the eyes to prevent any splashes from reaching the eyes.Goggles should form an airtight seal around the eye to prevent any splashes reaching the eyes.

In terms of body protection, long - sleeved laboratory coats or chemical - resistant coveralls should be worn.Wearing long-sleeved lab coats or chemical-resistant coveralls is the best way to protect your body. This protects the skin on the body from direct contact with the chemical.This will protect the skin from the chemical. If the chemical comes into contact with the skin, it may cause skin irritation, redness, itching, or even chemical burns depending on the duration and amount of contact.If the chemical is in contact with the skin it can cause irritation, redness, itchiness, or even chemical burning depending on the duration of the contact.

When it comes to hand protection, use chemical - resistant gloves.Use chemical-resistant gloves for hand protection. Nitrile gloves are often a good choice as they offer resistance to a wide range of chemicals.Nitrile gloves can be a good option as they are resistant to a variety of chemicals. Gloves should be inspected regularly for any signs of damage or leakage to ensure continuous protection.To ensure that gloves are always protected, they should be checked regularly for signs of damage or leakage.

In the workplace, ensure good ventilation.Assure good ventilation in the workplace. A well - ventilated area helps to disperse any vapors or fine particles of the chemical, reducing the concentration in the air.A well-ventilated area will help disperse any vapors of fine particles, reducing concentration in the air. This can be achieved through the use of fume hoods when performing tasks such as weighing, dissolving, or mixing the compound.Fume hoods can be used to reduce the concentration of the chemical in the air when performing tasks like weighing, dissolving or mixing.

Proper storage is also crucial.The right storage is also important. Store 3-(4 - Bromo - 2 - fluoro - phenyl)acrylic acid in a cool, dry place away from sources of heat, ignition, and incompatible substances.Store 3-(4-Bromo- 2-Fluoro- Phenyl)acrylic Acid in a cool and dry place, away from heat sources, ignitions, and incompatible materials. Keep it in a tightly - sealed container to prevent leakage and evaporation.Keep it in a tightly-sealed container to prevent leaking and evaporation. Label the container clearly with the chemical name, hazard warnings, and any relevant information.Label the container with the chemical name and any other relevant information.

In case of accidental exposure, have an emergency response plan in place.Prepare an emergency response plan for accidental exposure. If it gets on the skin, immediately wash the affected area with plenty of water for at least 15 minutes and remove any contaminated clothing.If it gets onto the skin, wash the area thoroughly with water for at least fifteen minutes and remove any contaminated clothes. For eye exposure, rinse the eyes thoroughly with water for an extended period and seek medical attention promptly.If you have been exposed to the substance through your eyes, wash them thoroughly with plenty of water for a long time and seek medical help immediately. If inhaled, move to fresh air and seek medical help if breathing difficulties persist.If inhaled move to fresher air and seek medical attention if breathing problems persist. In case of ingestion, do not induce vomiting unless directed by medical personnel and seek immediate medical assistance.In the event of ingestion, you should not induce vomiting without medical supervision and seek immediate medical attention.