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3-(4-hydroxyphenyl)acrylic Acid


Properties
Product Name 3-(4-Hydroxyphenyl)acrylic acid
Cas Number 501-98-4
Formula C9H8O3
Molar Mass 164.16
Property 1 White crystalline solid
Property 2 Melting point: 214-217°C
Property 3 Boiling point: 318.5°C at 760 mmHg
Property 4 Solubility: Soluble in water, alcohol, and ether
Property 5 Density: 1.265 g/cm³
Property 6 Acidity (pKa): 4.49
Property 7 Flash point: 174°C
Property 8 Refractive index: 1.590
Property 9 LogP: 1.29
Property 10 Appearance: Odorless solid
FAQ

What are the applications of 3-(4-Hydroxyphenyl)acrylic acid?

3-(4-Hydroxyphenyl)acrylic acid, also known as p -coumaric acid, has several important applications.
In the food industry, it plays a role as an antioxidant.It is used as an antioxidant in the food industry. Antioxidants help prevent the oxidation of fats, oils, and other food components, thus extending the shelf - life of food products.Antioxidants prevent the oxidation and degradation of fats, oils and other food components. This extends the shelf life of food products. By scavenging free radicals, 3-(4 - Hydroxyphenyl)acrylic acid can slow down the process of food spoilage, discoloration, and the development of off - flavors. It can be added to various food items such as processed meats, baked goods, and beverages.It can be added into various food items, such as baked goods, processed meats, and beverages. Additionally, it may contribute to the natural color and flavor stability of certain foods.It may also contribute to the natural color stability and flavor of certain foods.

In the pharmaceutical field, this compound shows potential for health - promoting effects.This compound has the potential to promote health in the pharmaceutical industry. It has been studied for its anti - inflammatory properties.Its anti-inflammatory properties have been studied. Inflammation is associated with many chronic diseases like arthritis, cardiovascular diseases, and some types of cancer.Inflammation has been linked to many chronic diseases such as arthritis, cardiovascular disease, and certain types of cancer. By reducing inflammation at the cellular level, 3-(4 - Hydroxyphenyl)acrylic acid may help in preventing or alleviating the symptoms of these diseases. It also exhibits antibacterial and antifungal activities.It also has antibacterial and antifungal properties. This can be useful in the development of new antibiotics or antifungal agents, especially considering the growing problem of antibiotic resistance.This can be used to develop new antifungal or antibiotic agents, especially in light of the increasing problem of antibiotic resistance. It may be used to combat harmful microorganisms that can cause infections in humans and animals.It can be used to fight harmful microorganisms which can cause infections in both humans and animals.

In the cosmetics industry, 3-(4 - Hydroxyphenyl)acrylic acid is valued for its skin - beneficial properties. Its antioxidant nature helps protect the skin from damage caused by free radicals, which are generated by environmental factors such as UV radiation, pollution, and smoking.Its antioxidant properties protect the skin against damage caused by free-radicals, which can be generated by environmental factors like UV radiation, pollution and smoking. This protection can slow down the aging process of the skin, reducing the appearance of wrinkles and age spots.This protection can slow the aging of the skin and reduce wrinkles and age spots. It may also have a role in skin whitening.It may also play a role in skin lightening. By inhibiting the activity of enzymes involved in melanin production, it can help to even out skin tone and reduce hyperpigmentation.It can even out the skin tone and reduce hyperpigmentation by inhibiting the enzymes that are involved in melanin.

In the agricultural sector, it can be used as a natural plant growth regulator.It can be used in the agricultural sector as a natural plant-growth regulator. It may influence various physiological processes in plants, such as seed germination, root and shoot growth, and flowering.It can influence a variety of physiological processes in plants such as seed germination and growth of roots and shoots. Moreover, its antibacterial and antifungal properties can also be exploited to protect crops from diseases, reducing the need for synthetic pesticides.Its antibacterial and antifungal qualities can also be used to protect crops against diseases, reducing their need for synthetic pesticides. This can contribute to more sustainable and environmentally - friendly agricultural practices.This can lead to more sustainable and environmentally-friendly agricultural practices.

What are the properties of 3-(4-Hydroxyphenyl)acrylic acid?

3-(4 - Hydroxyphenyl)acrylic acid, also known as p - coumaric acid, has several notable properties.
Physical properties:Physical Properties
In terms of appearance, 3-(4 - Hydroxyphenyl)acrylic acid is usually a white to light - yellow crystalline powder. It has a melting point in the range of around 212 - 214 degC.It has a melting temperature in the range 212-214 degC. This relatively high melting point is due to the presence of strong intermolecular forces such as hydrogen bonding.This high melting point is due in part to strong intermolecular interactions, such as hydrogen bonds. The hydroxyl group in the 4 - position of the phenyl ring can form hydrogen bonds with other molecules of the same compound, holding them tightly together in the solid state.The hydroxyl group at the 4 -position of the phenyl can form hydrogen bonding with other molecules in the same compound. This holds them tightly together in solid state.

It has limited solubility in water.It has a limited solubility when dissolved in water. The hydrophobic nature of the phenyl ring and the relatively non - polar double - bond region in the acrylic acid part contribute to this low solubility.This low solubility is due to the hydrophobic nature and non-polar double-bond region of the acrylic acid. However, it shows better solubility in polar organic solvents like ethanol, methanol, and dimethyl sulfoxide (DMSO).It is more soluble in polar organics such as ethanol, methanol and dimethyl sulfoxide.

Chemical properties:Chemical properties
The presence of the phenolic hydroxyl group makes 3-(4 - Hydroxyphenyl)acrylic acid a good antioxidant. The hydroxyl group can donate a hydrogen atom to free radicals, thereby neutralizing them and preventing oxidative damage.The hydroxyl group is able to donate a hydrogen atom, neutralizing free radicals and preventing oxidative damages. This property is significant in biological systems, as it can protect cells from damage caused by reactive oxygen species.This property is important in biological systems as it can protect the cells from damage caused reactive oxygen species.

The double bond in the acrylic acid moiety is reactive.The double bond of the acrylic acid moiety can be reactive. It can participate in various addition reactions.It can be involved in different addition reactions. For example, it can undergo Michael addition reactions, where a nucleophile adds to the double bond.It can, for example, undergo Michael addition reactions where a nucleophile is added to the double bond. This reactivity allows it to be used in organic synthesis to build more complex molecules.This reactivity can be used to build more complex organic molecules.

The carboxylic acid group is also reactive.The carboxylic group is also reactive. It can undergo typical carboxylic acid reactions such as esterification, where it reacts with an alcohol in the presence of an acid catalyst to form an ester.It can undergo typical carboxylic reactions, such as esterification. This is where it reacts in the presence of a catalyst acid with an alcohol to form an ester. This reaction is important in the production of esters of 3-(4 - Hydroxyphenyl)acrylic acid, which may have different applications compared to the parent compound.

Biological properties:Biological properties
3-(4 - Hydroxyphenyl)acrylic acid has been found to possess anti - inflammatory properties. It can inhibit the production of pro - inflammatory cytokines in cells, thus reducing the inflammatory response in the body.It can inhibit production of pro-inflammatory cytokines within cells, reducing inflammation in the body. It also shows some antibacterial and antifungal activities.It also has antibacterial and antifungal properties. These biological activities make it potentially useful in the development of drugs, nutraceuticals, and in food preservation to prevent spoilage caused by microorganisms.These biological properties make it useful in the development and production of drugs, nutraceuticals and food preservation products to prevent food spoilage due to microorganisms.

Is 3-(4-Hydroxyphenyl)acrylic acid safe to use?

3-(4 - Hydroxyphenyl)acrylic acid, also known as p - coumaric acid, is generally regarded as safe for use in many contexts.
In nature, it is widely distributed in plants.It is found in many plants. It can be found in fruits, vegetables, and grains.It is found in grains, fruits, and vegetables. This natural occurrence is one indication of its relatively low inherent toxicity.This is a natural occurrence that indicates its relatively low toxicity. In the human diet, it is consumed through the ingestion of various plant - based foods, and the human body has evolved to handle such substances without significant adverse effects.It is found in the human diet through various plant-based foods. The human body has evolved over time to be able to handle these substances without any significant adverse effects.

From a biochemical perspective, 3-(4 - Hydroxyphenyl)acrylic acid has antioxidant properties. It can scavenge free radicals in the body, which are harmful molecules that can damage cells and contribute to various diseases.It can neutralize free radicals, which are harmful molecules in the body that can damage cells or contribute to diseases. These antioxidant effects are beneficial, potentially reducing the risk of chronic diseases such as heart disease and certain cancers.These antioxidant effects can reduce the risk of chronic illnesses such as heart disease or certain cancers.

When it comes to its use in cosmetics, it is often included for its skin - protecting properties.Its skin-protective properties are often cited when it comes to its inclusion in cosmetics. Since it can combat oxidative stress caused by factors like UV radiation and pollution, it can help maintain skin health.It can maintain skin health by combating oxidative stress, which is caused by factors such as UV radiation and pollution. And as long as it is used within the recommended concentration limits, it is considered safe for topical application.As long as it's used within the recommended concentration limit, it's considered safe for topical use. There are regulations in place to ensure that cosmetic products containing this ingredient do not pose risks to consumers.Cosmetic products containing this substance are regulated to ensure they do not pose any risks to consumers.

In the food industry, it can be used as a natural preservative due to its antibacterial and antifungal properties.It can be used in the food industry as a natural preserver due to its antibacterial properties. This use helps extend the shelf - life of food products while being a more natural alternative to some synthetic preservatives.This helps to extend the shelf-life of food products and is a natural alternative to some synthetic preservers. It is also approved for use in food in many regions, further attesting to its safety when used appropriately.It is approved for use in foods in many regions. This further confirms its safety when used correctly.

However, like any substance, individual sensitivities may exist.As with any substance, there are individual sensitivities. Some people might be allergic to 3-(4 - Hydroxyphenyl)acrylic acid, although such cases are likely to be rare. Also, high - dose studies in animal models might show certain effects, but these may not directly translate to human safety concerns when used in normal, everyday applications.Also, studies on high-doses in animal models may show certain effects. However, these effects may not translate directly to human safety concerns if used in normal everyday applications. Overall, when used in appropriate amounts in food, cosmetics, and other applications, 3-(4 - Hydroxyphenyl)acrylic acid is considered a safe and beneficial compound.

What is the price of 3-(4-Hydroxyphenyl)acrylic acid?

The price of 3-(4-Hydroxyphenyl)acrylic acid can vary significantly depending on several factors.
Firstly, the purity of the compound plays a major role.First, the purity of a compound is important. Higher purity versions are generally more expensive.Higher purity versions tend to be more expensive. For example, a reagent - grade 3-(4-Hydroxyphenyl)acrylic acid with a purity of around 97 - 99% might be priced differently compared to a technical - grade product with a slightly lower purity. A high - purity product may be more suitable for applications in research, such as in pharmaceutical research where precise chemical properties are crucial.A high-purity product may be better suited for research applications, such as pharmaceutical research.

Secondly, the quantity purchased affects the price per unit.Second, the quantity purchased will affect the price per unit. Buying in bulk usually leads to a lower cost per gram or kilogram.Bulk purchases usually result in a lower price per gram or kilogram. If you are purchasing only a small amount, say a few grams for laboratory - scale experiments, the price per gram will be relatively high.If you only need a small quantity, such as a few grams to conduct laboratory experiments, then the price per gram is likely to be high. However, if a company needs large quantities, like hundreds of kilograms for industrial production, they can often negotiate a better price per unit with the supplier.If a company is buying large quantities of the product, such as hundreds of kilograms, for industrial production, it can negotiate a lower price per unit.

Thirdly, the source of the compound matters.Thirdly, it is important to consider the source of the compound. Different suppliers may have different pricing strategies.Different suppliers can have different pricing strategies. Some well - established chemical companies may charge more due to their reputation for quality control and reliable supply.Some chemical companies with a long history of quality control and reliable supplies may charge higher prices. On the other hand, emerging suppliers or those in regions with lower production costs may offer more competitive prices.On the other hand emerging suppliers or those located in regions with lower costs of production may offer more competitive pricing.

In general, on the laboratory chemical market, for small quantities (e.g., 1 - 5 grams) of high - purity 3-(4-Hydroxyphenyl)acrylic acid, the price could range from around $20 to $50 per gram. If purchasing in larger quantities, like 100 grams, the price per gram might drop to around $10 - $20.If you purchase in larger quantities like 100 grams, then the price per gram could drop to $10 - $20. For industrial - scale purchases in kilograms, the price per kilogram could be in the range of $500 - $1500, depending on all the factors mentioned above.The price per kilogram for industrial-scale purchases in kilograms could range from $500 to $1500 depending on the factors above.

It's also important to note that market conditions, such as supply and demand, can impact the price.Also, market conditions such as supply and demands can affect the price. If there is a sudden increase in demand, perhaps due to a new research breakthrough or an emerging industrial application, the price may rise.The price can rise if there is an unexpected increase in demand due to a new breakthrough in research or a new industrial application. Conversely, if there is an oversupply, the price may decline.In the event of an oversupply or shortage, prices may fall. Additionally, fluctuations in the cost of raw materials used to synthesize 3-(4-Hydroxyphenyl)acrylic acid can also affect its final price.

Where can I buy 3-(4-Hydroxyphenyl)acrylic acid?

3-(4-Hydroxyphenyl)acrylic acid, also known as 4-coumaric acid, is a chemical compound that can be purchased from various sources.
One of the primary places to buy it is from chemical suppliers.Chemical suppliers are the most common place to purchase this compound. Well - known chemical companies like Sigma - Aldrich, Alfa Aesar, and TCI Chemicals often stock this compound.This compound is often stocked by well-known chemical companies such as Sigma - Aldrich and Alfa Aesar. These suppliers typically offer high - purity products, which are suitable for scientific research, pharmaceutical development, and other applications that require precise chemical compositions.These suppliers offer high-purity products that are ideal for scientific research, pharmaceutical developments, and other applications requiring precise chemical compositions. They have extensive catalogs available online, where you can search for 3-(4 - Hydroxyphenyl)acrylic acid by its chemical name or relevant product codes. Ordering from these suppliers is relatively straightforward.It is easy to order from these suppliers. You create an account on their websites, add the desired quantity of the product to the cart, and proceed with the payment and shipping details.You create an online account, add the desired amount of the product to your cart, then proceed with payment and shipping. They usually ship to a wide range of locations around the world, but shipping costs and delivery times may vary depending on your location.They ship to many locations around the globe, but shipping rates and delivery times can vary based on your location.

Another option is to check with local chemical distributors.You can also check with local chemical distributors. These are companies that act as intermediaries between the large chemical manufacturers and end - users.These companies act as intermediaries for large chemical manufacturers. They might offer more personalized service and potentially better deals in terms of pricing, especially if you are a local customer.If you are a local client, they may offer better pricing and more personalized service. You can find local chemical distributors through business directories or by asking for recommendations from other professionals in the field, such as researchers in chemistry - related laboratories or chemical engineers.You can find local distributors of chemical products through business directories, or by asking other professionals to recommend them.

Online marketplaces that specialize in scientific and laboratory supplies can also be a source.Online marketplaces that are specialized in laboratory and scientific supplies can be another source. Platforms like Amazon Business (in some regions) or Alibaba may have sellers offering 3-(4 - Hydroxyphenyl)acrylic acid. However, when buying from such marketplaces, it is crucial to carefully check the seller's reputation, product reviews, and the authenticity of the product.When buying from such platforms, it's important to check the seller, the product reviews and the authenticity of the item. Some sellers may offer lower - quality or mislabeled products.Some sellers may offer products of lower quality or that are mislabeled.

In addition, if you are associated with an academic institution or a research laboratory, you can check if the institution has a preferred supplier or a purchasing system in place.If you are affiliated with an academic institution, or a laboratory for research, you can also check if they have a preferred supplier, or a purchasing program in place. Sometimes, institutions negotiate bulk purchase agreements with certain chemical suppliers, which can result in cost savings.Institutions can negotiate bulk purchase agreements, which may result in cost savings. You can reach out to the purchasing department or the laboratory manager to inquire about the process of obtaining 3-(4 - Hydroxyphenyl)acrylic acid through the institutional channels.