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3-ethoxyacrylic Acid Chloride


Properties
Product Name 3-Ethoxyacrylic acid chloride
Cas Number 6191-99-7
Formula C5H7ClO2
Molar Mass 134.56 g/mol
Boiling Point 158-160 °C
Density 1.171 g/cm³
Refractive Index n20/D 1.446
Flash Point 43 °C
Solubility Reacts with water
Appearance Colorless liquid
Vapor Pressure 0.4 mmHg at 25 °C
Stable Under Recommended Conditions Yes
Risk Statements R34: Causes burns
Precautionary Statements S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
FAQ

What are the applications of 3-ethoxyacrylic acid chloride?

3 - Ethoxyacrylic acid chloride is a reactive compound with several applications.3 - Ethoxyacrylic Acid Chloride is a reactive chemical with many applications.
In the field of organic synthesis, it serves as a crucial building block.It is a key building block in organic synthesis. It can be used in the formation of various esters.It can be used to form various esters. When reacted with different alcohols, it enables the creation of ethoxyacrylic esters.It can be used to create ethoxyacrylic esters by reacting with different alcohols. These esters are often utilized in the production of specialty polymers.These esters are used in the production specialty polymers. For instance, they can be incorporated into polymers to modify their physical properties, such as improving solubility or enhancing the flexibility of the resulting polymer materials.They can be used to modify the physical properties of polymers, such as increasing their solubility and flexibility.

It also plays an important role in the synthesis of pharmaceutical intermediates.It is also used in the synthesis and production of pharmaceutical intermediates. By reacting with appropriate amine - containing compounds, it can form amide - based intermediates.It can produce amide-based intermediates by reacting with appropriate amine-containing compounds. These amide - containing intermediates may then be further transformed into bioactive molecules.These amide-containing intermediates can be further transformed into bioactive molecule. Some of these bioactive molecules can potentially be developed into drugs that target specific biological pathways in the human body.Some of these bioactive molecule can be developed into drugs which target specific biological pathways within the human body. For example, they might be used in the development of drugs for treating certain inflammatory conditions or as potential anti - cancer agents.They could be used to develop drugs that treat certain inflammatory conditions, or as potential anti-cancer agents.

In the area of agrochemicals, 3 - ethoxyacrylic acid chloride can be involved in the synthesis of pesticides or herbicides.In the field of agrochemicals 3 - ethoxyacrylic chloride is used in the production of pesticides and herbicides. The unique structure of the compounds derived from it can confer specific biological activities.The unique structure can confer specific biological activity to the compounds derived from this acid chloride. Compounds synthesized using this acid chloride may have the ability to disrupt the normal physiological functions of pests or weeds.Compounds synthesized with this acid chloride could disrupt the normal physiological functions in pests or weeds. For example, they could interfere with the growth, reproduction, or metabolic processes of these organisms, thus providing an effective means of controlling agricultural pests and weeds.They could, for example, interfere with the growth or reproduction of these organisms.

Furthermore, in the production of fine chemicals, it is used to introduce specific functional groups into molecules.In the production of fine chemical, it is also used to introduce specific functional group into molecules. This can be essential for creating chemicals with precise properties required in various industries.This is essential when creating chemicals that have the precise properties needed in different industries. For example, in the fragrance and flavor industry, derivatives of 3 - ethoxyacrylic acid chloride can be used to synthesize unique aroma - or taste - imparting compounds.In the fragrance and flavor industries, for example, derivatives of 3-ethoxyacrylic chloride can be synthesized to create unique compounds that impart aroma or taste. These compounds can be added to products such as perfumes, food, and beverages to enhance their sensory appeal.These compounds can be used to enhance the sensory appeal of products like perfumes, foods, and beverages.

In summary, 3 - ethoxyacrylic acid chloride has diverse applications across multiple industries, from organic synthesis for polymers to the development of pharmaceuticals, agrochemicals, and fine chemicals.Summary: 3 - ethoxyacrylic chloride is used in a wide range of industries. Its applications include organic synthesis, pharmaceuticals, agrochemicals and fine chemicals. Its reactivity allows for the creation of a wide range of useful compounds that contribute to different aspects of modern life, from improving the performance of materials to safeguarding agricultural production and enhancing the quality of consumer products.Its reactivity allows the creation of a variety of useful compounds which contribute to various aspects of modern living, from improving the performance and quality of materials to safeguarding agriculture production and enhancing consumer products.

What are the safety precautions when handling 3-ethoxyacrylic acid chloride?

3 - ethoxyacrylic acid chloride is a chemical compound that requires careful handling due to its potentially hazardous nature.The ethoxyacrylic chloride chemical compound is potentially hazardous and requires special handling. Here are some safety precautions.Here are some safety tips.
Firstly, personal protective equipment (PPE) is essential.Personal protective equipment (PPE), is a must. Wear appropriate chemical - resistant gloves.Wear gloves that are resistant to chemicals. Nitrile gloves are often a good choice as they can resist many chemicals.Nitrile gloves can be a good option as they are resistant to many chemicals. This helps prevent direct skin contact, which could lead to skin irritation, burns, or absorption of the chemical into the body.This prevents direct skin contact that could cause skin irritation, burns or absorption of chemicals into the body. Additionally, put on safety goggles or a face shield to protect the eyes.Wear safety goggles, or a face shield, to protect your eyes. Chemical splashes in the eyes can cause severe damage, including permanent vision loss.Chemical splashes can cause serious damage to the eyes, including permanent loss of vision. A lab coat or other protective clothing should be worn to cover the body, reducing the risk of spills reaching the skin.Wearing a lab coat or other protective clothing will reduce the risk that spills will reach the skin.

Secondly, work in a well - ventilated area.Second, make sure you are working in an area that is well-ventilated. It is advisable to use a fume hood if possible.If possible, it is best to use a fume-hood. 3 - ethoxyacrylic acid chloride may release harmful vapors.Ethoxyacrylic Acid Chloride can release harmful vapors. Adequate ventilation helps to dilute these vapors, reducing the risk of inhalation.Adequate ventilation can dilute the vapors and reduce the risk of inhalation. Inhalation of the chemical can cause respiratory problems such as coughing, shortness of breath, and damage to the respiratory tract.Inhalation can cause respiratory problems, such as coughing and shortness of breathe, or damage to the respiratory system.

Thirdly, when handling the chemical, be careful to avoid spills.Thirdly, avoid spills when handling the chemical. Ensure that containers are properly sealed when not in use.When not in use, ensure that containers are sealed properly. If a spill occurs, immediately take appropriate clean - up measures.Take immediate action to clean up any spills. Small spills can be absorbed with an appropriate absorbent material, such as vermiculite or sand.Small spills can easily be absorbed by using an absorbent material such as vermiculite, sand or other suitable absorbent materials. Dispose of the contaminated absorbent according to local regulations.Dispose of contaminated absorbents according to local regulations. For larger spills, evacuate the area if necessary and notify the appropriate safety personnel.If the spill is larger, evacuate the area and notify the safety personnel.

Fourthly, do not eat, drink, or smoke in the area where 3 - ethoxyacrylic acid chloride is being handled.Fourthly, avoid eating, drinking, or smoking in the vicinity of 3 - ethoxyacrylic chloride. This helps prevent ingestion of the chemical, which could have serious health consequences.This will help prevent ingestion, which can have serious health effects. Wash hands thoroughly after handling the chemical to remove any potential residues.After handling the chemical, wash your hands thoroughly to remove any residues.

Finally, be aware of the reactivity of 3 - ethoxyacrylic acid chloride.Be aware of the reactivity 3 - ethoxyacrylic chloride. It may react with water, alcohols, and other common substances.It can react with alcohols, water, and other substances. Store it away from incompatible materials to prevent dangerous reactions.Store it away incompatible materials to avoid dangerous reactions. Read and understand the safety data sheet (SDS) for the chemical before handling it, as the SDS provides detailed information on hazards, safety precautions, and first - aid measures.Before handling the chemical, read and understand the safety information sheet (SDS). The SDS contains detailed information about hazards, safety precautions and first-aid measures.

How is 3-ethoxyacrylic acid chloride synthesized?

3 - ethoxyacrylic acid chloride is an important organic synthesis intermediate.The ethoxyacrylic chloride is a key organic synthesis intermediate. Here is a common synthesis method:Here is a common method of synthesis:
1. Starting materials preparationStart materials preparation
The synthesis often starts from 3 - ethoxyacrylic acid.Synthesis often begins with 3 - ethoxyacrylic acids. This acid can be obtained through a series of reactions.This acid can be produced through a series reactions. For example, ethyl acetoacetate can be reacted with ethanol under the action of a base such as sodium ethoxide to form an intermediate, which is then further hydrolyzed and decarboxylated to get 3 - ethoxyacrylic acid.For example, ethylacetoacetate reacts with ethanol when a base like sodium ethoxide is present to form an intermediary. This intermediate can then be hydrolyzed and decarboxylated in order to obtain 3 - ethoxyacrylic acids.

2. Conversion to acid chlorideConversion to acid chloride
Once 3 - ethoxyacrylic acid is obtained, it is converted to its acid chloride form.Once 3 - ethoxyacrylic is obtained, it must be converted to its acid chloride. The most common reagent for this conversion is thionyl chloride (SOCl2).This conversion is most commonly performed with thionyl chloride (SOCl2). The reaction mechanism involves the substitution of the -OH group of the carboxylic acid with a -Cl group.The mechanism of the reaction involves the substitution of a -Cl with the -OH of the carboxylic acids.

The reaction is carried out as follows: Place 3 - ethoxyacrylic acid in a suitable reaction flask.The reaction is performed as follows: Place the 3 - ethoxyacrylic in a suitable reaction flask. Add an appropriate amount of thionyl chloride.Add a suitable amount of thionylchloride. A catalytic amount of a base like pyridine can be added.Add a catalytic amount such as pyridine. Pyridine helps to activate the reaction by binding to the acidic hydrogen of the carboxylic acid, facilitating the attack of the thionyl chloride.Pyridine activates the reaction by binding with the acidic hydrogen in the carboxylic acids, facilitating the attack by the thionyl chloride.

The reaction proceeds with the evolution of sulfur dioxide (SO2) and hydrogen chloride (HCl) gases.The reaction proceeds by releasing sulfur dioxide (SO2), and hydrogen chloride gases (HCl). The chemical equation for the reaction of 3 - ethoxyacrylic acid (R - COOH) with thionyl chloride can be written as: R - COOH+SOCl2-R - COCl + SO2+HClThe chemical equation of the reaction between 3 - ethoxyacrylic (R – COOH) and thionyl chloride can be written: R – COOH+SOCl2-R- COCl+ SO2+HCl

During the reaction, it is necessary to control the reaction temperature.During the reaction it is important to control the temperature. Usually, the reaction can be carried out at a moderate temperature, such as around 40 - 60 degC.The reaction can usually be carried out at moderate temperatures, such as 40-60 degC. Higher temperatures may lead to side reactions, while lower temperatures may slow down the reaction rate significantly.Higher temperatures can cause side reactions while lower temperatures can slow down the rate of reaction.

After the reaction is complete, the excess thionyl chloride can be removed by distillation under reduced pressure.The excess thionyl can be removed after the reaction by distillation at reduced pressure. The remaining product is 3 - ethoxyacrylic acid chloride, which can be further purified by techniques such as distillation or recrystallization depending on the purity requirements of the final product.The remaining product, 3 - ethoxyacrylic chloride, can be purified further by techniques such distillation or crystallization depending on the purity requirement of the final product.

It should be noted that during the synthesis process, proper safety precautions need to be taken.During the synthesis process it is important to take safety precautions. Thionyl chloride is a corrosive and volatile chemical, and the evolved sulfur dioxide and hydrogen chloride gases are toxic and harmful.Thionyl Chloride is a volatile and corrosive chemical. The gases produced by the synthesis are toxic and harmful. Adequate ventilation and personal protective equipment should be used.Personal protective equipment and adequate ventilation should be used.

What are the physical and chemical properties of 3-ethoxyacrylic acid chloride?

3 - ethoxyacrylic acid chloride is an organic compound with distinct physical and chemical properties.The organic compound ethoxyacrylic chloride has distinct physical and chemical characteristics.
Physical Properties

Appearance: It is likely to be a color - less to light - colored liquid under standard conditions.Appearance: Under standard conditions, it is likely to appear as a liquid of a lighter to less intense color. This is common for many acyl chloride compounds, especially those with relatively short carbon - chain substituents.This is common in many acyl - chloride compounds. The ethoxy group (-OCH2CH3) and the unsaturated acrylic acid - related structure contribute to its overall physical state.The ethoxy (-OCH2CH3) group and the unsaturated acryl acid - related structural component contribute to its overall state.

Boiling Point: The boiling point of 3 - ethoxyacrylic acid chloride is influenced by its molecular structure.Boiling point: The molecular structure of 3 - ethoxyacrylic chloride influences its boiling point. The presence of the polar carbonyl chloride group (C = O - Cl) and the ethoxy group, along with the unsaturated carbon - carbon double bond in the acrylic acid part, results in a certain degree of intermolecular forces.The presence of a polar carbonyl group (C = O-Cl) and an ethoxy group in the acrylic acid component, together with the unsaturated double carbon-carbon bond, results in intermolecular force. The polar carbonyl chloride group can participate in dipole - dipole interactions, while the ethoxy group can contribute to van der Waals forces.The polar carbonyl group can participate in dipole-dipole interactions, whereas the ethoxy can contribute to van der Waals force. Generally, acyl chlorides have relatively high boiling points compared to non - polar hydrocarbons of similar molecular weight due to these polar interactions.Due to these polar interactions, acyl halides generally have higher boiling points than non-polar hydrocarbons with similar molecular weight. However, compared to compounds with strong hydrogen - bonding capabilities, their boiling points are lower.Their boiling points are lower compared to compounds that have strong hydrogen-bonding capabilities.

Solubility: It is sparingly soluble in water.It is sparingly water soluble. This is because when 3 - ethoxyacrylic acid chloride comes into contact with water, it reacts readily (as will be discussed in chemical properties).This is because 3 - ethoxyacrylic chloride reacts readily with water (as discussed in chemical properties). In organic solvents, it shows good solubility.It is soluble in organic solvents. Organic solvents such as dichloromethane, chloroform, and ethyl acetate can dissolve it well.Dichloromethane chloroform and ethyl Acetate are organic solvents that can dissolve it. These solvents have similar non - polar or moderately polar characteristics to 3 - ethoxyacrylic acid chloride, following the principle of "like dissolves like."These solvents are similar to 3 -ethoxyacrylic chloride in terms of non-polar or moderately-polar characteristics, according to the principle "like dissolves as."

Chemical Properties

Reactivity with Water: One of the most characteristic chemical properties of 3 - ethoxyacrylic acid chloride is its high reactivity towards water.Reactivity with water: 3 - ethoxyacrylic chloride has a high reactivity to water. The carbonyl chloride group is highly electrophilic.The carbonyl group is highly electrophilic. Water molecules can act as nucleophiles, attacking the carbon atom of the carbonyl group.Water molecules can act like nucleophiles and attack the carbon atom in the carbonyl group. This reaction leads to the hydrolysis of 3 - ethoxyacrylic acid chloride.This reaction leads the hydrolysis of 3- ethoxyacrylic chloride. The end - products of hydrolysis are 3 - ethoxyacrylic acid and hydrochloric acid.The hydrolysis end-products are 3 -ethoxyacrylic and hydrochloric acids. The reaction is exothermic and proceeds rapidly, which is typical of acyl chloride hydrolysis reactions.The reaction is exothermic, and proceeds quickly. This is typical for acyl chloride reactions.

Reaction with Alcohols: 3 - ethoxyacrylic acid chloride reacts with alcohols to form esters.Reaction with Alcohols : 3 - Ethoxyacrylic Acid Chloride reacts alcohols to produce esters. The alcohol's hydroxyl group (-OH) acts as a nucleophile, attacking the electrophilic carbon of the carbonyl chloride group.The hydroxyl group of the alcohol (-OH), acts as a nucleophile and attacks the electrophilic carbon in the carbonyl chloride. Chloride ion is then eliminated, and an ester linkage is formed.The chloride ion then is eliminated and an ester bond is formed. For example, when reacting with methanol, it will produce the corresponding methyl 3 - ethoxyacrylate and hydrogen chloride.When reacting with methanol it will produce the corresponding hydrogen chloride and methyl 3-ethoxyacrylate. This reaction is an important method for the synthesis of esters, and it can be catalyzed by bases in some cases to increase the reaction rate.This reaction is a key method for the synthesis and ethoxyacrylate. It can be catalyzed in some cases by bases to increase the rate of the reaction.

Reaction with Amines: Amines can also react with 3 - ethoxyacrylic acid chloride.Amines can also react 3 - ethoxyacrylic chloride. The lone pair of electrons on the nitrogen atom of the amine acts as a nucleophile, attacking the carbonyl carbon.The single pair of electrons of the nitrogen atom in the amine acts like a nucleophile and attacks the carbonyl carbon. Chloride is displaced, and an amide is formed.The chloride is displaced and an amide forms. This reaction is useful in the synthesis of amides, which are important functional groups in many pharmaceuticals and polymers.This reaction is used to synthesize amides which are functional groups that are important in many pharmaceuticals and other polymers. The reaction can be carried out in the presence of a base to neutralize the hydrogen chloride generated during the reaction.The reaction can be carried in the presence a base, which will neutralize the hydrogen chloride produced during the reaction.

What are the storage requirements for 3-ethoxyacrylic acid chloride?

3 - ethoxyacrylic acid chloride is a chemical compound with specific storage requirements due to its reactivity and potential hazards.3 - Ethoxyacrylic Acid Chloride is a chemical compound that has specific storage requirements because of its reactivity.
Firstly, it should be stored in a cool and dry place.It should be stored in an area that is cool and dry. High temperatures can accelerate chemical reactions, leading to decomposition or polymerization of 3 - ethoxyacrylic acid chloride.High temperatures can speed up chemical reactions and lead to the decomposition or polymerization 3 - ethoxyacrylic chloride. A temperature range between 2 - 8 degrees Celsius is often ideal for many reactive chemicals, and this compound might follow a similar pattern.Many reactive chemicals respond best to a temperature range of 2 - 8 degrees Celsius. This compound may follow a similar pattern. Storing it in a dry environment is crucial because moisture can react with the acid chloride group.It is important to store it in a completely dry environment because moisture can react and cause the acid chloride group to react. Water can hydrolyze 3 - ethoxyacrylic acid chloride, breaking the acyl - chloride bond and forming the corresponding carboxylic acid and hydrogen chloride gas.Water can hydrolyze 3-ethoxyacrylic chloride, breaking down the acyl-chloride bond to form carboxylic acid gas and hydrogen chloride. This not only ruins the chemical but also releases corrosive and harmful hydrogen chloride.This process not only destroys the chemical, but also releases harmful and corrosive hydrogen chloride.

Secondly, it must be stored in a well - ventilated area.Second, it should be stored in an area that is well-ventilated. If any leakage or decomposition occurs, the potentially harmful fumes such as hydrogen chloride can be quickly dissipated.The fumes, such as hydrogen chloride, can quickly dissipate if there is a leakage or a decomposition. A poorly ventilated storage space can lead to the accumulation of these fumes, creating a dangerous environment for anyone entering the area.Poorly ventilated storage spaces can lead to an accumulation of these fumes and create a dangerous environment. Additionally, good ventilation helps to maintain a stable temperature as heat can be carried away.A good ventilation system can also help to maintain a constant temperature by allowing heat to be carried away.

Thirdly, it should be stored away from incompatible substances.It should also be stored away. This includes amines, alcohols, and strong bases.This includes alcohols, amines and strong bases. Amines can react with the acid chloride group to form amides, while alcohols can form esters.Alcohols can react with acid chloride groups to form esters, while amines can react with the group. Strong bases can initiate various reactions, often leading to the degradation of the compound.Strong bases can initiate a variety of reactions, which often lead to the degradation or the compound. For example, a reaction with an amine could result in the formation of an unwanted by - product and the loss of the desired 3 - ethoxyacrylic acid chloride.A reaction with an amino acid could lead to the formation of unwanted by-products and the loss of desired 3 - ethoxyacrylic chloride.

Fourthly, the storage container is of great importance.The storage container is also very important. It should be made of a material that is resistant to corrosion by 3 - ethoxyacrylic acid chloride.It should be made from a material resistant to corrosion caused by 3-ethoxyacrylic chloride. Glass containers with tightly - sealed lids are often a good choice as glass is relatively inert to many chemicals.Glass containers with tightly-sealed lids are a good option as glass is relatively inert towards many chemicals. However, if there is a risk of breakage, high - density polyethylene or other suitable plastic containers might be considered, provided they have been tested and proven to be compatible with the compound.If there is a possibility of breakage, then high-density polyethylene or another suitable plastic container may be considered. However, they must have been tested to ensure compatibility with the compound. The container should be clearly labeled with the name of the chemical, its hazards, and storage conditions.The container should clearly be labeled, stating the name of the compound, its hazards and storage conditions.

Finally, proper inventory management is essential.Lastly, it is important to have a good inventory management system. Regularly check the storage conditions and the integrity of the containers.Check the storage conditions regularly and the integrity of containers. Any signs of leakage, discoloration, or unusual odors should be investigated immediately.Investigate immediately any signs of leakage or discoloration. Rotate the stock to ensure that older batches are used first, reducing the risk of long - term storage - related degradation.Rotate the stock so that older batches are used before the newer ones. This will reduce the risk of degradation due to long-term storage.