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3-ethyoxyacrylic Acid


Properties
Product Name 3-Ethoxyacrylic acid
Cas Number 3967-59-3
Formula C5H8O3
Molar Mass 116.12 g/mol
Property 1 Appearance: Clear colorless liquid
Property 2 Boiling Point: 180-182 °C
Property 3 Density: 1.1 g/cm³
Property 4 Refractive Index: 1.430
Property 5 Solubility: Soluble in water
Property 6 Flash Point: 64 °C
Property 7 Melting Point: Not applicable
Property 8 Vapor Pressure: 0.46 mmHg at 25 °C
Property 9 pKa: 4.44
Property 10 LogP: -0.28
FAQ

What are the applications of 3-Ethyoxyacrylic acid?

3 - Ethoxyacrylic acid is a chemical compound with several important applications.3 - Ethoxyacrylic Acid is a chemical compound that has many important applications.
One significant application is in the field of organic synthesis.One important application is in organic synthesis. It serves as a valuable building block for the creation of more complex organic molecules.It is a useful building block to create more complex organic molecules. Due to the presence of the ethoxy and acrylic acid functional groups, it can participate in various chemical reactions.It can be used in a variety of chemical reactions due to the presence ethoxy- and acrylic acid-functional groups. For example, the acrylic acid moiety can undergo polymerization reactions.The acrylic acid moiety, for example, can undergo polymerization. By reacting 3 - Ethoxyacrylic acid with appropriate monomers, copolymers can be synthesized.Copolymers are synthesized by reacting 3 - Ethoxyacrylic Acid with monomers. These copolymers may have unique properties depending on the comonomers used, such as altered solubility, mechanical strength, or adhesion characteristics.These copolymers can have unique properties based on the comonomers they use, such as altered mechanical strength or adhesion. This makes them useful in the production of specialty polymers for applications like coatings, adhesives, and films.This makes them useful for the production of specialty materials such as coatings, films, and adhesives.

In the pharmaceutical industry, 3 - Ethoxyacrylic acid can play a role in drug synthesis.In the pharmaceutical industry 3 - Ethoxyacrylic Acid can play a part in drug synthesis. Its reactive functional groups can be utilized to introduce specific structural elements into drug molecules.Its reactive functional group can be used to introduce specific structural components into drug molecules. These structural modifications can potentially enhance the pharmacological properties of the resulting drugs.These structural modifications may enhance the pharmacological characteristics of the resulting drug. For instance, it can be used to attach certain side - chains that improve the drug's solubility, bioavailability, or target - binding affinity.It can be used, for example, to attach certain side-chains that improve the drug’s solubility or bioavailability. This allows for the development of more effective and efficient drugs.This allows for the creation of more efficient and effective drugs.

3 - Ethoxyacrylic acid is also relevant in the area of materials science.Ethoxyacrylic Acid is also relevant to materials science. As mentioned earlier, its ability to form polymers can be exploited to create materials with tailored properties.As previously mentioned, its ability form polymers allows for the creation of materials with tailored properties. In the development of smart materials, polymers derived from 3 - Ethoxyacrylic acid could potentially respond to external stimuli such as changes in temperature, pH, or light.In the development and use of smart materials, polymers made from 3 - Ethoxyacrylic Acid could respond to external stimuli, such as changes in temperature or pH. This responsiveness can be designed into the polymer structure during synthesis.This responsiveness can also be built into the polymer during synthesis. For example, a pH - sensitive polymer made from 3 - Ethoxyacrylic acid could be used in controlled - release drug delivery systems.A pH-sensitive polymer made of 3 - Ethoxyacrylic Acid could be used to deliver controlled-release drugs. In an acidic environment (such as the stomach), the polymer might change its conformation and release the encapsulated drug, while remaining stable in other body environments.In an acidic environment, such as the stomach, the polymer may change its conformation to release the drug encapsulated.

Furthermore, in the agrochemical industry, 3 - Ethoxyacrylic acid derivatives may have applications.3 - Ethoxyacrylic acids derivatives could also be used in the agrochemical sector. They could potentially be used to develop new pesticides or plant growth regulators.They could be used to create new plant growth regulators or pesticides. The chemical structure of 3 - Ethoxyacrylic acid can be modified to target specific biological processes in pests or plants.The chemical structure of 3 Ethoxyacrylic Acid can be modified to target biological processes in plants or pests. For example, by creating molecules that interfere with the metabolic pathways of pests, it can help in the development of more environmentally friendly and effective pest control agents.By creating molecules that interfere in the metabolic pathways of insects, it is possible to develop more environmentally friendly and efficient pest control agents. Similarly, for plant growth regulators, derivatives of 3 - Ethoxyacrylic acid could be designed to regulate plant growth and development, such as promoting root growth or enhancing flowering.Derivatives of 3 – Ethoxyacrylic Acid could also be used to regulate plant growth, such as by promoting root growth and flowering. Overall, 3 - Ethoxyacrylic acid has diverse applications across multiple industries, contributing to the development of new and improved products.Overall, 3 – Ethoxyacrylic Acid has diverse applications in multiple industries and contributes to the development of improved products.

What are the properties of 3-Ethyoxyacrylic acid?

3 - Ethoxyacrylic acid is an organic compound with several notable properties.Ethoxyacrylic Acid is a compound with many notable properties.
Physical properties

In terms of its physical state, it is typically a liquid at room temperature.It is usually a liquid when it is at room temperature. Its boiling point is an important characteristic.Its boiling temperature is an important characteristic. Due to the presence of the carboxylic acid group and the ethoxy side - chain, the boiling point is influenced by factors such as intermolecular hydrogen bonding and van der Waals forces.The presence of the carboxylic group and the side-chain ethoxy influences the boiling point. The carboxylic acid group can form strong hydrogen bonds with other molecules of 3 - ethoxyacrylic acid, which generally elevates the boiling point compared to compounds without such strong intermolecular interactions.The carboxylic group can form strong hydrogen bonding with other molecules of 3-ethoxyacrylic acids, which in turn raises the boiling temperature compared to compounds that do not have such strong intermolecular interactions.

The compound is likely to be soluble in polar organic solvents.The compound will likely be soluble in organic solvents that are polar. The carboxylic acid group is polar, and the ethoxy group also contributes to the overall polarity of the molecule to some extent.The carboxylic group is polar and the ethoxy groups also contribute to the overall polarity. It can dissolve in solvents like ethanol, methanol, and acetone.It can dissolve in solvents such as ethanol, methanol and acetone. However, its solubility in water is more limited.Its solubility in liquid water is limited. While the carboxylic acid group can form hydrogen bonds with water molecules, the relatively large non - polar ethoxy group reduces the overall hydrophilicity of the molecule, resulting in only partial solubility in water.The carboxylic group can form hydrogen bond with water molecules. However, the relatively large, non-polar ethoxy groups reduces the overall hydrophilicity, resulting in a partial solubility.

Chemical properties

The carboxylic acid group in 3 - ethoxyacrylic acid is highly reactive.The carboxylic group in 3 - Ethoxyacrylic Acid is highly reactive. It can undergo typical carboxylic acid reactions.It can undergo typical carboxylic acids reactions. For example, it can react with bases in an acid - base neutralization reaction.It can, for example, react with bases to neutralize an acid-base reaction. When treated with a base like sodium hydroxide, it forms the corresponding carboxylate salt and water.When it is treated with a hydroxide base, such as sodium hydroxide forms the carboxylate salts and water.

The double bond in the acrylic acid part of the molecule gives it the ability to participate in addition reactions.The double bond in acrylic acid gives it the ability for addition reactions. It can react with electrophiles in electrophilic addition reactions.It can react with other electrophiles to form electrophilic additions. For instance, it can react with halogens like bromine to form a dibromo - substituted product across the double bond.It can, for example, react with halogens such as bromine to produce a dibromo-substituted product across the double bonds. Radical addition reactions are also possible, where a radical species can add to the double bond, initiating a polymerization or other chain - growth reactions.Radical addition reactions can also occur, where a radical species adds to the double-bond, initiating polymerizations or other chain-growth reactions.

The ethoxy group can also be involved in reactions.The ethoxy can also be involved with reactions. Under certain conditions, it can be cleaved in a hydrolysis reaction.It can be cleaved under certain conditions in a hydrolysis. For example, in the presence of strong acids or bases and heat, the ethoxy group can be removed, and the resulting product would be acrylic acid along with ethanol as a by - product.In the presence of strong bases or acids and heat, for example, the ethoxy can be removed and the resultant product would be acrylic and ethanol as by-products.

3 - Ethoxyacrylic acid can also participate in esterification reactions.Ethoxyacrylic acids can also participate in esterification. The carboxylic acid group can react with an alcohol in the presence of an acid catalyst to form an ester.In the presence of an acid catalyser, the carboxylic acid group reacts with an alcohol to form an ester. This property makes it useful in the synthesis of various esters, which may have applications in the fragrance, flavor, and plasticizer industries.This property makes it useful for the synthesis of different esters that may have applications in the scent, flavor, or plasticizer industries.

In summary, 3 - ethoxyacrylic acid has a combination of physical and chemical properties that are characteristic of its functional groups, and these properties make it a valuable compound in organic synthesis and potentially in various industrial applications.Summary: 3 - ethoxyacrylic acids have a combination physical and chemical characteristics that are characteristic of their functional groups. These properties make it an important compound in organic synthesis, and potentially in a variety of industrial applications.

How is 3-Ethyoxyacrylic acid synthesized?

3 - Ethoxyacrylic acid can be synthesized through the following general approach.The following general approach can be used to synthesize ethoxyacrylic acids.
1. Preparation of starting materialsPrepare the starting materials
One common starting material is ethyl acetoacetate.Ethyl Acetoacetate is a common starting material. Ethyl acetoacetate can be obtained through the Claisen condensation of ethyl acetate.Ethyl Acetoacetate is obtained by the Claisen condensation. In this reaction, sodium ethoxide is used as a base.In this reaction, sodium isothoxide acts as a base. Two molecules of ethyl acetate react under the action of sodium ethoxide.Under the influence of sodium ethoxide, two molecules of ethyl-acetate react. The ethoxide ion deprotonates one molecule of ethyl acetate at the a - carbon, creating a nucleophilic enolate ion.The ethoxide deprotonates a molecule of ethyl-acetate at its a-carbon, creating a nucleophilic and enolate. This enolate then attacks the carbonyl carbon of another ethyl acetate molecule, followed by elimination of an ethoxide ion to form ethyl acetoacetate.This enolate attacks the carbonyl-carbon of another ethyl-acetate molecule.

2. Conversion to 3 - ethoxyacrylic acid derivativeConversion to 3-ethoxyacrylic Acid Derivative
Ethyl acetoacetate is then subjected to ethylation.Ethylacetoacetate will then be ethylated. For example, it can react with an ethylating agent such as ethyl iodide in the presence of a base like potassium carbonate.It can, for example, react with an agent that ethylates such as ethyliodide when a base such as potassium carbonate is present. The base deprotonates the a - carbon of ethyl acetoacetate, and the resulting enolate anion reacts with ethyl iodide to form an ethyl - substituted intermediate.The base deprotonates a-carbon of ethylacetoacetate and the resulting anion reacts ethyliodide in order to form an intermediate ethyl-substituted.

Next, the ethyl - substituted ethyl acetoacetate derivative is subjected to a hydrolysis - decarboxylation sequence.The ethyl-substituted ethyl-acetoacetate is then subjected to the hydrolysis-decarboxylation process. Hydrolysis of the ester group in the presence of an acid or a base can convert the ethyl - substituted ethyl acetoacetate into the corresponding carboxylic acid.The ester group can be hydrolyzed in the presence of a base or an acid to produce the carboxylic acid. For base - catalyzed hydrolysis, an aqueous solution of sodium hydroxide can be used.Aqueous sodium hydroxide solution can be used for base-catalyzed hydrogenation. The ester group is cleaved, forming the carboxylate salt.The ester group is cleaved to form the carboxylate. Acidification of the carboxylate salt with a strong acid like hydrochloric acid gives the free carboxylic acid.The carboxylate salt is acidified with a strong base like hydrochloric to give the free carboxylic acids.

Finally, decarboxylation occurs upon heating the resulting carboxylic acid.The carboxylic acid is heated to complete the decarboxylation. The b - keto - acid intermediate formed during the hydrolysis step undergoes decarboxylation.Decarboxylation is performed on the b-keto-acid intermediate formed during hydrolysis. The carboxyl group is lost as carbon dioxide, and a double bond is formed in the process, resulting in the formation of 3 - ethoxyacrylic acid.The carboxyl group, which is carbon dioxide, is lost in the process. A double bond is also formed, resulting in 3 - ethoxyacrylic acids.

Another possible route could involve starting from malonic acid derivatives.Another route would be to start with malonic acid derivatives. Malonic acid esters can be alkylated with an appropriate ethyl - containing reagent to introduce the ethoxy group at the desired position.The ethoxy group can be introduced at the desired location by alkylating malonic acid esters with an ethyl-containing reagent. Subsequent hydrolysis and decarboxylation steps similar to those described above can lead to the formation of 3 - ethoxyacrylic acid.Similar hydrolysis and decarboxylation processes can be followed to form 3 - ethoxyacrylic acids. However, the synthesis from ethyl acetoacetate is more straightforward and commonly used in laboratory - scale preparations due to the relatively easy availability of ethyl acetoacetate and the well - established reaction conditions for its subsequent modifications.The synthesis of ethylacetoacetate, however, is easier and more commonly used for laboratory-scale preparations because ethylacetoacetate can be readily obtained and the reaction conditions are well-established.

What are the safety precautions when handling 3-Ethyoxyacrylic acid?

When handling 3 - Ethoxyacrylic acid, several safety precautions should be followed.Safety precautions must be observed when handling 3 - Ethoxyacrylic Acid.
First, personal protective equipment (PPE) is crucial.Personal protective equipment (PPE), or PPE, is essential. Wear appropriate chemical - resistant gloves.Wear gloves that are resistant to chemicals. Nitrile gloves are often a good choice as they can provide a barrier against the acid.Nitrile gloves can be a good option as they provide a barrier to the acid. This helps prevent skin contact, which can lead to irritation, burns, or possible absorption of the chemical into the body.This will help prevent skin contact that can cause irritation, burns or absorption of the chemical. Additionally, use safety goggles or a face shield to protect the eyes.Use safety goggles, or a face shield, to protect your eyes. A splash of 3 - Ethoxyacrylic acid into the eyes can cause severe damage, including burns and potential vision impairment.A splash of 3 – Ethoxyacrylic Acid in the eyes can cause severe eye damage, including possible vision impairment and burns.

Second, proper ventilation is essential. Work in a well - ventilated area, preferably under a fume hood if possible.Work in an area that is well-ventilated, preferably under a fumehood. This acid may release vapors that can be irritating to the respiratory system.This acid can release vapors which can irritate the respiratory system. Inhalation of these vapors can cause coughing, shortness of breath, and irritation of the nose and throat.Inhaling these vapors may cause coughing, shortness in breath, and irritation to the nose and throat. Adequate ventilation helps to disperse the vapors, reducing the risk of inhalation exposure.Adequate ventilation can help disperse vapors and reduce the risk of exposure.

Third, when storing 3 - Ethoxyacrylic acid, keep it in a cool, dry place away from sources of heat and ignition.Third, store 3 - Ethoxyacrylic Acid in a cool and dry place, away from heat sources and ignition. It is important to store it in a tightly - sealed container to prevent leakage and evaporation.Store it in a tightly-sealed container to prevent leaking and evaporation. Also, store it separately from incompatible substances.Store it away from other substances that are incompatible. For example, acids should be kept away from bases as they can react violently.Acids should be kept separate from bases, as they can react violently.

Fourth, in case of skin contact, immediately rinse the affected area with plenty of water for at least 15 minutes.In the event of skin contact, rinse the affected area immediately with plenty of water and for at least 15 min. Remove any contaminated clothing during the rinsing process.During the rinsing, remove any contaminated clothing. After that, seek medical attention if the irritation persists.If irritation persists, seek medical help. If the acid gets into the eyes, immediately flush the eyes with copious amounts of water for at least 15 minutes, holding the eyelids open.If the acid gets in the eyes, flush them with water for 15 minutes while keeping the eyelids wide open. Then, get urgent medical help.Get immediate medical attention. In the event of inhalation, move to fresh air immediately.In the event of an inhalation, get to fresh air as soon as possible. If breathing is difficult, provide oxygen if available and call for emergency medical services.If breathing is difficult, use oxygen if it's available and call emergency medical services.

Finally, when handling the acid, be careful not to spill it.When handling the acid, take care not to spill any. In case of a spill, contain the spill area to prevent the spread of the acid.Contain the spill area in order to prevent the spread. Use appropriate absorbent materials, such as sand or a chemical - specific spill kit, to clean up the spill.To clean up a spill, use absorbent materials such as sand, or a chemical-specific spill kit. Dispose of the contaminated absorbent materials in accordance with local regulations for hazardous waste.Dispose the contaminated absorbent material in accordance with local regulations on hazardous waste.

What are the storage requirements for 3-Ethyoxyacrylic acid?

3 - Ethoxyacrylic acid has specific storage requirements to maintain its quality and safety.To maintain its quality and safety, ethoxyacrylic acids must be stored in a specific way.
Firstly, it should be stored in a cool place.It should be kept in a cool, dry place. High temperatures can accelerate chemical reactions, potentially leading to decomposition or polymerization of 3 - Ethoxyacrylic acid.High temperatures can accelerate chemical reaction, which could lead to the decomposition or polymerization 3 - Ethoxyacrylic Acid. A storage temperature preferably below 25 degrees Celsius is ideal.Ideal is a storage temperature below 25 degrees Celsius. This helps to slow down any thermally - induced degradation processes that could change the chemical structure of the compound.This will help to slow down any thermally-induced degradation processes which could change the chemical composition of the compound.

Secondly, it must be stored in a dry environment.Second, it should be stored in a completely dry environment. Moisture can react with 3 - Ethoxyacrylic acid.Moisture may react with 3 – Ethoxyacrylic Acid. Water might hydrolyze the ester - like structure present in 3 - Ethoxyacrylic acid, if any, or cause other side reactions.Water could hydrolyze any ester-like structure present in the 3 - Ethoxyacrylic Acid, or cause side reactions. This could result in the formation of unwanted by - products and a reduction in the purity of the acid.This could lead to the formation of unwanted by-products and a decrease in the purity of acid. Storage areas should be well - protected from sources of humidity, such as leaky roofs or pipes.Stored areas should be protected from sources of moisture, such as leaking roofs or pipes.

Thirdly, 3 - Ethoxyacrylic acid should be stored in a tightly sealed container.Thirdly, 3- Ethoxyacrylic Acid should be stored in an airtight container. Exposure to air can also pose risks.Air exposure can also be dangerous. Oxygen in the air may oxidize the acid over time, which can affect its chemical properties.Over time, oxygen in the air can oxidize the acids and affect their chemical properties. A proper seal on the storage container prevents air from entering, thus minimizing the potential for oxidation reactions.Proper sealing of the storage container will prevent air from entering and minimize the possibility of oxidation reactions. Suitable containers for storage include glass or certain types of plastics that are resistant to the corrosive nature of the acid.Glass or plastics resistant to acid corrosion are suitable containers for storage.

Fourthly, keep it away from incompatible substances.Keep it away from substances that are incompatible. 3 - Ethoxyacrylic acid is an acidic compound.3 - Ethoxyacrylic Acid is an acidic compound. It should be stored separately from strong bases, as they will react violently with the acid.It should not be stored near strong bases as they will react violently. Additionally, avoid storing it near reactive metals that could potentially react with the acid to form metal salts and release hydrogen gas.Avoid storing it in the vicinity of metals that are reactive and could react with it to form metal salts or release hydrogen gas.

Finally, proper labeling of the storage container is crucial.Labeling the container properly is also important. The label should clearly indicate the name of the compound, its chemical properties, any hazard warnings, and the date of storage.Labels should clearly state the name of the compound and its chemical properties. They should also include any warnings about hazards, as well as the date of storage. This ensures that handlers can easily identify the substance and take appropriate safety precautions.This allows the handlers to easily identify the substance, and take safety precautions. It also helps in inventory management and tracking the age of the stored 3 - Ethoxyacrylic acid, as older samples may be more prone to degradation.This helps with inventory management and determining the age of stored 3 - Ethoxyacrylic acids, as older samples are more susceptible to degradation. By adhering to these storage requirements, the integrity and usability of 500 grams or any quantity of 3 - Ethoxyacrylic acid can be maintained over an extended period.By following these storage requirements, 500 grams of 3 - Ethoxyacrylic Acid or any other quantity can be kept in a usable condition for a long time.