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Product Name | cis-a,b-Dimethylacrylic acid |
Cas Number | 541-47-9 |
Formula | C5H8O2 |
Molar Mass | 100.12 g/mol |
Melting Point | 22-24 °C |
Boiling Point | 184-186 °C |
Density | 0.972 g/cm³ |
Vapor Pressure | 0.4 mmHg at 25 °C |
Refractive Index | 1.4310 |
Flash Point | 86 °C |
Solubility In Water | Slightly soluble |
Pka | 4.83 |
Appearance | Colorless liquid |
Odor | Pungent odor |
What are the main applications of cis-a%252Cb-Dimethylacrylic acid?
Cis-a,b - Dimethylacrylic acid, also known as tiglic acid, has several important applications.The tiglic acid (also known as Cis-a-b-dimethylacrylic acid) has many important applications.
In the field of pharmaceuticals, it can serve as a key intermediate in the synthesis of various drugs.It can be used as a key chemical intermediate in the pharmaceutical industry to synthesize various drugs. For example, some antibacterial and anti - inflammatory medications may incorporate structures derived from cis - a,b - Dimethylacrylic acid.Some antibacterial and anti-inflammatory medications, for example, may contain structures derived from dimethylacrylic acid cis-a,b. Its unique chemical structure can participate in reactions that build complex molecular frameworks necessary for the biological activity of these drugs.Its unique chemical composition can be used in reactions to build complex molecular structures necessary for these drugs' biological activity. By reacting with other chemical compounds, it can help form the active ingredients that target specific disease - causing agents or inflammatory pathways in the body.It can react with other chemical compounds to form active ingredients that target specific disease-causing agents or inflammation pathways in the body.
In the fragrance and flavor industry, cis - a,b - Dimethylacrylic acid plays a role.In the fragrance and flavor industries, cis-a,b-dimethylacrylic acid is used. It can be used to create certain esters through esterification reactions.It can be used in esterification reactions to create certain esters. These esters often have pleasant scents and flavors.These esters have pleasant flavors and scents. Some of them may be used in perfumes to add a unique, fruity or floral - like undertone.Some of these esters can be added to perfumes to give them a fruity or floral undertone. In the food industry, these esters can be used as flavor enhancers.These esters are used in the food industry as flavor enhancers. For instance, they might be added to beverages, confectionery, or baked goods to impart a special, appealing taste.They can be added to baked goods, confectionery or beverages to give them a unique, appealing flavor.
The polymer industry also benefits from cis - a,b - Dimethylacrylic acid.The polymer industry can also benefit from cis-a,b-dimethylacrylic acid. It can be copolymerized with other monomers.It can be copolymerized. When copolymerized, it can modify the properties of the resulting polymers.It can be copolymerized to modify the properties of polymers. For example, it can improve the thermal stability, mechanical strength, and chemical resistance of the polymers.It can, for example, improve the polymers' thermal stability, mechanical resistance, and chemical resistance. These modified polymers are then used in a wide range of applications, such as in the production of plastics for packaging materials, where enhanced barrier properties against moisture and gases are required.These modified polymers can be used in a variety of applications. For example, they are used to produce plastics for packaging, where improved barrier properties against gases and moisture are needed. In addition, they can be used in coatings, providing better adhesion and durability to the surfaces they are applied to.They can also be used as coatings to improve adhesion and durability of surfaces.
In the agricultural sector, derivatives of cis - a,b - Dimethylacrylic acid may have potential as plant growth regulators.Derivatives of cis-a,b-dimethylacrylic acids may be useful as plant growth regulators in the agricultural sector. They can influence various physiological processes in plants, such as seed germination, root development, and flowering.They can influence a variety of physiological processes in plants such as seed germination and root development. By carefully controlling the application of these derivatives, farmers may be able to improve crop yields, enhance the quality of produce, and increase the resistance of plants to environmental stresses like drought or disease.Farmers may be able, by carefully controlling the application, to increase crop yields, improve the quality of the produce, and increase plant resistance to environmental stresses such as drought or disease. Overall, cis - a,b - Dimethylacrylic acid has diverse applications across multiple industries, contributing to the development of many essential products.Overall, cis-a,b-dimethylacrylic acid is used in many industries and contributes to the development of essential products.
What are the properties of cis-a%252Cb-Dimethylacrylic acid?
Cis - a,b - Dimethylacrylic acid, also known as (Z)-2 - methyl - 2 - butenoic acid, has several distinct properties.The properties of (Z)-2-methyl - 2- butenoic acids, also known by the name Cis a,b-dimethylacrylic acid are quite distinct.
Physical properties:Physical Properties
In terms of appearance, it is a colorless to pale - yellow liquid.It is a colorless or pale-yellow liquid. It has a pungent, unpleasant odor.It has an unpleasant, pungent odor. The compound has a relatively low boiling point.The compound has a low boiling point. This is because the intermolecular forces in cis - a,b - Dimethylacrylic acid are mainly dipole - dipole interactions and hydrogen bonding.The intermolecular interactions in cis-a,b-dimethylacrylic acids are mainly dipole-dipole interactions and hydrogen bonds. The hydrogen bonding occurs due to the presence of the carboxylic acid (-COOH) group.The carboxylic acid group (-COOH), which is present in the molecule, causes hydrogen bonding. However, compared to larger molecules with more extensive intermolecular forces, its boiling point is not extremely high.Its boiling point is lower than larger molecules that have more extensive intermolecular interactions.
The melting point of cis - a,b - Dimethylacrylic acid is also influenced by these intermolecular forces.These intermolecular forces also influence the melting point of cis-a,b-dimethylacrylic acid. The carboxylic acid group can form strong hydrogen - bonded dimers, which affects the packing of molecules in the solid state.The carboxylic group can form strong hydrogen-bonded dimers which affects the packing in the solid state. This results in a melting point that is characteristic of a compound with relatively strong yet not overly dominant intermolecular forces.This results in a melting temperature that is typical of a compound that has relatively strong but not overly dominant intermolecular interactions.
Chemical properties:Chemical properties
The most prominent feature of cis - a,b - Dimethylacrylic acid is the presence of the carboxylic acid functional group.The carboxylic group is the most distinctive feature of cis-a,b-dimethylacrylic acid. This group is acidic.This group is acidic. In an aqueous solution, it can donate a proton (H+) to form a carboxylate anion.In an aqueous solvent, it can donate one proton (H+), forming a carboxylate ion. The acidity is due to the resonance stabilization of the carboxylate ion.Acidity is caused by the resonance stabilization. The two oxygen atoms in the - COO - group share the negative charge, making the conjugate base relatively stable.The two oxygen atoms of the -COO - group have the same negative charge, which makes the conjugate base relatively stabile.
The double bond in cis - a,b - Dimethylacrylic acid also endows it with reactivity.The double bond in the cis-a,b- Dimethylacrylic Acid also gives it reactivity. It can participate in addition reactions.It can also participate in other reactions. For example, it can react with hydrogen in the presence of a catalyst such as palladium to form 2 - methylbutanoic acid through hydrogenation.It can, for example, react with hydrogen and a catalyst like palladium in order to form 2 -methylbutanoic acids through hydrogenation. It can also react with halogens like bromine in an addition reaction, where the double bond breaks and bromine atoms add across the double bond.It can also be used to react with halogens such as bromine, whereby the double bonds are broken and the bromine atoms are added across the double bonds.
Cis - a,b - Dimethylacrylic acid can also undergo esterification reactions.Dimethylacrylic Acid can also undergo esterification. When reacted with an alcohol in the presence of an acid catalyst, such as sulfuric acid, an ester is formed.When an alcohol is reacted with in the presence an acid catalyst such as sulfuric, an ester forms. The carboxylic acid group reacts with the - OH group of the alcohol, eliminating a molecule of water in the process.The carboxylic group reacts with -OH group of alcohol, removing a water molecule in the process. This reaction is important in the synthesis of various esters, which can have applications in the fragrance and flavor industry.This reaction is crucial in the synthesis and application of different esters in the fragrance industry.
In terms of its cis - configuration, it has different properties compared to its trans - isomer.Its cis-configuration has different properties than its trans-isomer. The cis - configuration can cause some steric hindrance due to the proximity of the two methyl groups on the same side of the double bond.The cis-configuration can cause steric hindrance because of the proximity of two methyl groups to each other on the same side as the double bond. This steric factor can influence its reactivity in some reactions and also affect its physical properties such as solubility and melting point when compared to the trans - isomer.This steric factor may affect its reactivity and physical properties, such as its solubility and melting temperature when compared with the trans-isomer.
How is cis-a%252Cb-Dimethylacrylic acid synthesized?
Cis - a,b - Dimethylacrylic acid can be synthesized through the following general approach.The following general approach can be used to synthesize Cis-a,b-dimethylacrylic acid.
One common method involves starting from suitable precursors.A common method is to start with suitable precursors. For example, it can be synthesized from isobutyraldehyde.It can be made from isobutyraldehyde, for example. The synthesis typically proceeds through a series of chemical reactions.The synthesis is usually carried out through a series chemical reactions. First, isobutyraldehyde can react with a reagent in a condensation reaction.In a condensation reaction, isobutyraldehyde reacts with a reagent. This condensation reaction often involves an enolate - type intermediate formation.This condensation reaction involves an enolate-type intermediate formation.
An aldol - like condensation can be carried out.A condensation similar to aldol can be performed. Isobutyraldehyde can react with another carbonyl - containing compound or a reagent capable of generating a nucleophilic species that attacks the carbonyl group of isobutyraldehyde.Isobutyraldehyde reacts with another carbonyl-containing compound or a chemical reagent that can generate a nucleophilic species capable of attacking the carbonyl group in isobutyraldehyde. Through this condensation step, a new carbon - carbon bond is formed, building the basic carbon skeleton of the desired dimethylacrylic acid structure.This condensation step forms a new carbon-carbon bond, which is the basis of the dimethylacrylic acid structure.
After the formation of the carbon - carbon bond in the condensation product, subsequent steps are usually required to introduce the carboxylic acid functionality.After the formation of a carbon-carbon bond in the condensation product is usually required, additional steps are usually needed to introduce the carboxylic acids functionality. This can be achieved through oxidation reactions.This can be done through oxidation reactions. For instance, if the intermediate has an alcohol or aldehyde group in a position suitable for oxidation to a carboxylic acid, an appropriate oxidizing agent can be used.If the intermediate contains an alcohol or an aldehyde in a position that is suitable for oxidation into a carboxylic acids, then an appropriate oxidizing agents can be used. Commonly, oxidizing agents like potassium permanganate or chromic acid derivatives can be employed under carefully controlled reaction conditions to selectively oxidize the relevant functional group to the carboxylic acid.Commonly, oxidizing substances like potassium permanganate and chromic acid derivates can be used under carefully controlled conditions to selectively oxidize a functional group into a carboxylic acid.
During the synthesis, reaction conditions such as temperature, reaction time, and the stoichiometry of the reactants play crucial roles.During the syntheses, conditions such as temperature and reaction time are crucial. The temperature needs to be optimized to ensure that the desired reactions occur at a reasonable rate without promoting side reactions.The temperature must be optimized so that the desired reaction occurs at a reasonable pace without promoting side-reactions. For example, in the condensation reaction, if the temperature is too high, it may lead to over - condensation or decomposition of the reactants.In the condensation reaction for example, if the temperatures are too high, they can lead to an over-condensation or decomposition. The reaction time also affects the yield and purity of the product.The reaction time can also affect the yield and purity. Insufficient reaction time may result in incomplete formation of the desired intermediate or final product, while excessive reaction time may cause degradation or further unwanted reactions.Insufficient reaction times can result in incomplete formation or degradation of the desired intermediate product or final product.
The stoichiometry of the reactants must be carefully adjusted.The stoichiometry must be adjusted carefully. If there is an excess of one reactant, it may lead to side reactions or make the purification of the final product more difficult.A reaction that is too strong can cause side reactions, or make it more difficult to purify the final product. After the synthesis is complete, purification steps such as distillation, recrystallization, or chromatography may be necessary to obtain pure cis - a,b - Dimethylacrylic acid.Purification steps, such as recrystallization or chromatography, may be required after the synthesis to obtain pure cis-a,b-dimethylacrylic acid. These purification methods help to separate the product from unreacted starting materials, by - products, and reaction intermediates.These purification methods are used to separate the final product from unreacted materials, by-products, and reaction intermediates.
What is the purity of cis-a%252Cb-Dimethylacrylic acid usually?
The purity of cis-a,b - Dimethylacrylic acid can vary significantly depending on its source and the manufacturing or purification processes it has undergone.The purity of cis a,b Dimethylacrylic Acid can vary greatly depending on the source and the manufacturing processes or purification it has undergone.
In laboratory - synthesized samples, with careful purification techniques such as recrystallization, column chromatography, or distillation, relatively high purities can be achieved.Purities of up to 95% can be achieved in laboratory-synthesized samples using purification techniques like recrystallization or column chromatography. For research - grade cis - a,b - Dimethylacrylic acid prepared in well - equipped chemical laboratories, purities often exceed 95%.Purities of research-grade cis-a,b-dimethylacrylic acids prepared in well-equipped chemical laboratories often exceed 95%. Recrystallization, for example, can be an effective method.Recrystallization is one method that can be effective. By dissolving the crude acid in a suitable solvent at an elevated temperature and then slowly cooling the solution, the pure compound crystallizes out, leaving impurities in the solution.The pure compound is crystallized by dissolving the crude acids in a suitable solvent and cooling it slowly. Multiple rounds of recrystallization can further enhance the purity.Multiple rounds of recrystallization will further improve the purity.
Industrial - scale production may have different purity levels.Purity levels may vary in industrial-scale production. If the production is aimed at applications where extremely high purity is not a strict requirement, such as in some basic chemical reactions or as a starting material in less - sensitive processes, the purity might be in the range of 80 - 90%.Purity levels may be 80-90 percent if the production is for applications where ultra-purity is not required, such as some basic chemical reactions, or as a starter material in less-sensitive processes. This is because achieving very high purities on an industrial scale can be costly and time - consuming.It is difficult and expensive to achieve very high purity on an industrial scale. Industrial purification methods might involve distillation processes, but due to the scale and cost - benefit considerations, it may not be feasible to purify to extremely high levels.Due to scale and cost-benefit considerations, industrial purification methods may involve distillation processes. However, it may not always be possible to purify at extremely high levels.
If cis - a,b - Dimethylacrylic acid is sourced from natural products and then isolated, the initial purity can be quite low, perhaps around 50 - 70%.If cis-a,b-dimethylacrylic acid is obtained from natural products, and then isolated, its initial purity may be low, around 50-70 percent. Natural sources often contain a complex mixture of compounds, and the isolation process to obtain the pure acid can be challenging.The natural sources are often a complex mixture, and isolating the pure acid from them can be difficult. Additional purification steps are usually required to increase the purity to a more useful level.Purification steps are often required to bring the acid to a useful level.
In some cases, if the cis - a,b - Dimethylacrylic acid is part of a mixture where it is used in a reaction without prior high - level purification, its effective purity can be considered in the context of the reaction's tolerance to impurities.In some cases, the cis-a,b- Dimethylacrylic Acid can be used in a reaction that does not require high-level purification. Its effective purity is then considered in relation to the reaction's tolerance of impurities. Some reactions may be able to tolerate a relatively low purity of the starting acid, as long as the impurities do not interfere significantly with the reaction mechanism or product formation.Some reactions can tolerate a relatively low level of purity in the starting acid as long as it does not interfere with the reaction mechanism. However, for applications such as pharmaceutical synthesis or high - end materials production, a purity of at least 98 - 99% may be required to ensure consistent product quality and avoid unwanted side - reactions.For applications such as pharmaceutical synthesis and high-end materials production, a minimum purity of 98-99% may be required in order to ensure product quality, and avoid unwanted side-reactions.
What safety precautions should be taken when handling cis-a%252Cb-Dimethylacrylic acid?
When handling cis-a,b - Dimethylacrylic acid, several safety precautions should be observed.Safety precautions must be observed when handling cis a,b Dimethylacrylic Acid.
First, personal protective equipment (PPE) is crucial.Personal protective equipment (PPE), or PPE, is essential. Wear appropriate chemical - resistant gloves.Wear gloves that are resistant to chemicals. Nitrile gloves are often a good choice as they can provide a barrier against the acid.Nitrile gloves can be a good option as they provide a barrier to the acid. This helps prevent skin contact, which can lead to irritation, burns, or allergic reactions.This can help prevent skin contact that could lead to irritations, burns or allergic reactions. Additionally, safety goggles or a face shield should be worn.Safety goggles or face shields should also be worn. The acid can splash, and getting it in the eyes is extremely dangerous, potentially causing serious eye damage, including loss of vision.Acid can splash and if it gets in your eyes, it could cause serious eye damage including loss of sight. A lab coat or other protective clothing should cover the body to safeguard against spills onto the skin and clothing.To protect against spills on the skin and clothing, a lab coat or other protective clothing is recommended.
Ventilation is another key aspect.Ventilation plays a key role. Cis - a,b - Dimethylacrylic acid may release fumes.Dimethylacrylic Acid (Cis-a,b) may emit fumes. Working in a well - ventilated area, preferably under a fume hood, is essential.It is important to work in an area that is well-ventilated, preferably under a hood. The fume hood will draw away any potentially harmful vapors, reducing the risk of inhalation.The fume hood will remove any potentially harmful vapors and reduce the risk of inhalation. Inhalation of these fumes can irritate the respiratory tract, causing coughing, shortness of breath, and in severe cases, more serious respiratory problems.Inhaling these fumes may cause irritation of the respiratory tract. This can lead to coughing, shortness in breath, or even more serious respiratory problems.
When handling the acid, proper handling techniques must be followed.Acid handling must be done with care. Always add the acid slowly to water, not the other way around.Add the acid to the water slowly, not the opposite. This is because the dilution process of an acid in water is exothermic.The dilution of an acid with water is exothermic. Adding water to acid can cause a violent reaction, leading to splashing due to the rapid release of heat.Addition of water to acid can result in a violent reaction that may cause splashing as a result of the rapid release heat. Use appropriate glassware or plastic containers that are compatible with the acid.Use glassware or containers made of plastic that are compatible with acid. Avoid using materials that can react with the acid, such as certain metals, which could cause corrosion and potentially dangerous reactions.Avoid using metals that may react with the acid. This could cause corrosion or other potentially dangerous reactions.
Storage is also important.It is also important to store the acid properly. Keep cis - a,b - Dimethylacrylic acid in a cool, dry place away from sources of heat and ignition.Keep cis-a,b-dimethylacrylic acid away from heat sources and ignition. It should be stored separately from incompatible substances, such as bases, reducing agents, and oxidizing agents.Store it separately from other incompatible substances such as bases, reducing and oxidizing agents. This separation helps prevent accidental reactions that could result in the release of heat, gases, or other hazardous by - products.This separation helps to prevent accidental reactions which could result in the release or hazardous by-products such as heat, gases and other substances.
In case of a spill, have a spill kit readily available.Have a spill kit on hand in case of an emergency. First, evacuate the area if the spill is large or if fumes are spreading.If the spill is large, or if fumes spread, first evacuate the area. For small spills, absorb the acid with an appropriate absorbent material, such as vermiculite or sand.For small spills absorb the acid using an appropriate absorbent, such as vermiculite, sand, or other suitable absorbent materials. Then, clean the area thoroughly with a suitable neutralizing agent, following the safety guidelines for the disposal of the contaminated absorbent and neutralizing waste.Then, thoroughly clean the area with a neutralizing agent. Follow the safety guidelines on how to dispose of the contaminated neutralizing and absorbent waste.
Finally, ensure that all personnel handling cis - a,b - Dimethylacrylic acid are properly trained.Final, ensure that all personnel who handle cis-a,b-dimethylacrylic acid is properly trained. They should be aware of the potential hazards associated with the acid and know how to respond in case of an emergency, such as contacting the appropriate emergency services and following first - aid procedures for skin or eye exposure.They should be trained on the hazards of the acid, and how to respond in an emergency.