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Furan-3-acrylic Acid


Properties
Product Name Furan-3-acrylic acid
Cas Number 110654-56-5
Formula C7H6O3
Molar Mass 138.12
Property 1 boiling_point_high
Property 2 moderate_solubility_in_water
Property 3 light_yellow_solid
Property 4 weak_carboxylic_acid_character
Property 5 aromatic_furan_ring_structure
Property 6 low_vapor_pressure
Property 7 reactive_double_bond
Property 8 capable_of_forming_esters
Property 9 susceptible_to_polymerization
Property 10 environmentally_sensitive
FAQ

What are the applications of furan-3-acrylic acid?

Furan - 3 - acrylic acid has several important applications.Furan -3 - acrylic acid is used in a variety of applications.
In the field of pharmaceuticals, it serves as a key intermediate.It is a key ingredient in pharmaceuticals. Its unique chemical structure allows for the synthesis of various bioactive compounds.Its unique chemistry allows the synthesis of bioactive compounds. For example, some derivatives of furan - 3 - acrylic acid can be designed to target specific biological pathways.Some derivatives of furan-3-acryl acid, for example, can be designed to target certain biological pathways. They may have antibacterial properties, helping to combat harmful bacteria.They may have antibacterial qualities, which can help combat harmful bacteria. By interfering with the bacteria's cell wall synthesis or metabolic processes, these derivatives can inhibit the growth and spread of bacteria.These derivatives can stop the growth of bacteria by interfering with their cell wall synthesis and metabolic processes. In addition, it may also play a role in the development of drugs for treating certain inflammatory diseases.It may also be used to develop drugs to treat certain inflammatory diseases. Compounds derived from it can potentially modulate the body's immune response, reducing inflammation and alleviating associated symptoms.Compounds derived therefrom can modulate the immune response of the body, reducing inflammation and relieving associated symptoms.

In the realm of materials science, furan - 3 - acrylic acid can be used in the preparation of specialty polymers.Furan - 3-acrylic acid is used to prepare specialty polymers in the field of materials science. When incorporated into polymer matrices, it can impart unique properties.It can be incorporated into polymer matrixes to impart unique properties. For instance, polymers containing furan - 3 - acrylic acid units may have enhanced thermal stability.Polymers containing furan-3-acrylic acid units, for example, may have improved thermal stability. This makes them suitable for applications where high - temperature resistance is required, such as in the manufacturing of components for the aerospace industry.This makes them ideal for applications requiring high-temperature resistance, such as the manufacture of components in the aerospace industry. These polymers can withstand the extreme temperatures experienced during flight, ensuring the durability and safety of the aircraft parts.These polymers are able to withstand the extreme temperature changes that occur during flight. This ensures the durability and safety for aircraft parts. Moreover, the functional groups in furan - 3 - acrylic acid can enable cross - linking reactions in polymers.Furan - 3-acrylic acid also contains functional groups that can be used to cross-link polymers. Cross - linked polymers often have improved mechanical strength, making them useful in the production of high - performance plastics for automotive applications.Cross-linked polymers are often stronger mechanically, making them useful for the production of high-performance plastics used in automotive applications.

In the area of organic synthesis, furan - 3 - acrylic acid is a valuable building block.Furan - 3-acrylic acid is an important building block in the field of organic synthesis. Chemists can utilize its double bond and furan ring to perform a variety of reactions.Chemists use its double bond and furan rings to perform a wide range of reactions. It can participate in Diels - Alder reactions, which are powerful methods for constructing complex cyclic structures.It can be used in Diels-Alder reactions which are powerful ways to construct complex cyclic structure. These cyclic compounds can then be further modified and functionalized to create a wide range of organic molecules with different properties and applications.These cyclic compounds are then further modified and functionalized in order to create a variety of organic molecules that have different properties and applications. Additionally, its reactivity can be exploited in coupling reactions, allowing for the formation of carbon - carbon or carbon - heteroatom bonds.Its reactivity can also be exploited to form carbon-carbon or carbon-heteroatom bonds. This versatility in organic synthesis enables the creation of new compounds with tailored properties for various fields, from dyes and pigments to agrochemicals.This versatility in organic syntheses allows the creation of new compounds that have tailored properties for a variety of fields, from dyes and agrochemicals to dyes and pigments.

Overall, furan - 3 - acrylic acid's applications span multiple important industries, highlighting its significance in modern chemistry and materials - based technologies.Furan - 3 acrylic acid is used in a wide range of industries, which highlights its importance in modern chemistry.

What are the properties of furan-3-acrylic acid?

Furan - 3 - acrylic acid has several important properties.Furan -3 - acrylic acid is a chemical with several important properties.
Physical properties:Physical Properties
In terms of appearance, furan - 3 - acrylic acid is typically a solid at room temperature.Furan - 3 acrylic acid appears as a solid when it is at room temperature. It has a defined melting point, which is an important characteristic for identifying and purifying the compound.It has a defined melt point, an important characteristic to identify and purify the compound. Precise determination of the melting point can help in assessing its purity, as impurities usually lower and broaden the melting range.The melting point can be used to determine the purity of a compound, since impurities tend to lower the melting range and increase it.

Solubility is another key physical property.Solubility is a key physical property. It shows some solubility in polar organic solvents.It is soluble in polar organic solvents. For example, it may dissolve to a certain extent in alcohols like methanol or ethanol due to the presence of polar functional groups in both the solvent and the molecule.It may, for example, dissolve to some extent in alcohols such as methanol orethanol due to the presence polar functional groups both in the solvent and molecule. The carboxylic acid group in furan - 3 - acrylic acid can form hydrogen bonds with the polar solvents, facilitating dissolution.Furan - 3- acrylic acid's carboxylic acid group can form hydrogen bond with polar solvents to facilitate dissolution. However, its solubility in non - polar solvents such as hexane is likely to be very low because the non - polar part of the furan - 3 - acrylic acid molecule is relatively small compared to the polar carboxylic acid group.Its solubility in non-polar solvents like hexane will be low, because the non-polar part of furan -3 - acrylic acids molecule is small compared to its polar carboxylic group.

Chemical properties:Chemical properties
The carboxylic acid group in furan - 3 - acrylic acid is highly reactive.The carboxylic group in furan-3-acrylic acid is highly reactive. It can undergo typical acid - base reactions.It can undergo typical acid-base reactions. For instance, it can react with bases such as sodium hydroxide to form the corresponding carboxylate salt and water.It can, for example, react with bases like sodium hydroxide in order to form the carboxylate salts and water. This property is useful in separating and purifying the compound from mixtures.This property can be used to separate and purify the compound from mixtures. It can also participate in esterification reactions.It can also be used in esterification reactions. When reacted with alcohols in the presence of an acid catalyst, it forms esters.When it reacts with alcohols, in the presence an acid catalyst, esters are formed. These esters may have different physical and chemical properties compared to the original acid, and they can be used in various applications such as in the fragrance and flavor industry.These esters can have different chemical and physical properties than the original acid. They can be used for various applications, such as the fragrance and flavor industries.

The double bond in the acrylic acid part of the molecule also endows it with reactivity.The double bond in acrylic acid gives it reactivity. It can undergo addition reactions.It can undergo addition reaction. For example, it can react with halogens like bromine through an electrophilic addition mechanism.It can, for example, react with halogens such as bromine via an electrophilic additive mechanism. The double bond can also be involved in polymerization reactions.Double bonds can also be involved with polymerization reactions. Under appropriate conditions, furan - 3 - acrylic acid monomers can polymerize to form polymers.Furan - 3 acrylic acid monomers are capable of polymerizing under the right conditions. These polymers may have unique properties depending on the structure and composition of the repeating units, and they can potentially be used in materials science applications.These polymers can have unique properties depending upon the structure and compositions of the repeating unit. They could be used for materials science applications.

The furan ring in the molecule also contributes to its chemical properties.Its chemical properties are also influenced by the furan ring. It is aromatic to some extent, although less aromatic than benzene.It is aromatic in some degree, but less aromatic than benzene. The furan ring can participate in reactions characteristic of aromatic compounds, such as electrophilic aromatic substitution reactions.The furan ring is capable of participating in aromatic compound reactions, such as electrophilic aromatic substitute reactions. These reactions can be used to introduce other functional groups onto the furan ring, expanding the chemical versatility of furan - 3 - acrylic acid and its derivatives.These reactions can be used for the introduction of other functional groups on the furan rings, increasing the chemical versatility and furan-3-acrylic acid and its derivatives.

How is furan-3-acrylic acid synthesized?

Furan - 3 - acrylic acid can be synthesized through several methods.Furan -3 - acrylic acid is synthesized in several ways. One common approach involves a Knoevenagel condensation reaction.One common method involves a Knoevenagel reaction.
In this method, furfural, which contains the furan ring with an aldehyde group, is used as a starting material.Furfural, a starting material that contains the furan ring and an aldehyde, is used in this method. Furfural reacts with malonic acid in the presence of a base catalyst.Furfural reacts in the presence a base catalyst with malonic acid. The base typically used can be pyridine.The base that is usually used is pyridine. Pyridine acts to deprotonate malonic acid, generating a reactive enolate ion.Pyridine deprotonates malonic acid to produce a reactive enolate.

The enolate ion from malonic acid then attacks the carbonyl carbon of furfural.The carbonyl carbon in furfural is attacked by the enolate ion of malonic acid. This nucleophilic addition forms an intermediate.This nucleophilic reaction forms an intermediate. Subsequently, a dehydration step occurs.Then, a step of dehydration occurs. The carboxylic acid group in the intermediate loses a molecule of water, facilitated by the basic reaction conditions and the nature of the intermediate structure.The carboxylic group in the intermediate loses one molecule of water due to the nature of the structure and the basic reaction conditions. This dehydration leads to the formation of a double bond, resulting in the synthesis of furan - 3 - acrylic acid.This dehydration results in the formation of a second bond, which leads to the synthesis furan-3-acrylic acid.

Another possible synthetic route could involve using other precursors that can be functionalized to introduce the furan ring and the acrylic acid moiety.Another possible route to synthesize the furan ring would be to use other precursors which can be functionalized in order introduce the acrylic acid moiety. For example, starting from a furan derivative with a suitable leaving group.Starting from a derivative of furan with a suitable 'leaving group'. This leaving group can be displaced by a reagent containing the acrylic acid - forming functionality through a substitution reaction.This leaving group can then be replaced by a reagent that contains the acrylic acid, forming functionality via a substitution reaction. However, this approach may require more complex synthetic steps to prepare the starting materials and control the reaction conditions to ensure the proper formation of the desired product.This approach may require more complicated synthetic steps to prepare starting materials and to control the reaction conditions in order to ensure that the desired product is formed.

The Knoevenagel condensation - based synthesis is relatively straightforward and commonly used due to the availability of furfural and malonic acid as starting materials, and the mild reaction conditions provided by the use of pyridine as a catalyst.The Knoevenagel condensation-based synthesis is relatively simple and widely used because it uses pyridine to provide mild reaction conditions. After the synthesis, the product can be purified through techniques such as recrystallization from an appropriate solvent system, which helps to remove any unreacted starting materials, by - products, or catalyst residues, obtaining pure furan - 3 - acrylic acid.Purification of the product is possible by using techniques such as recrystallization in an appropriate solvent system. This helps to remove unreacted starting materials or by-products, and catalyst residues.

What are the safety precautions when handling furan-3-acrylic acid?

When handling furan - 3 - acrylic acid, several safety precautions should be taken.Safety precautions must be taken when handling furan -3 - acrylic acid.
First, personal protective equipment (PPE) is essential.Personal protective equipment (PPE), first and foremost, is essential. Wear appropriate chemical - resistant gloves.Wear chemical-resistant gloves. Nitrile gloves are often a good choice as they can provide a certain degree of protection against contact with furan - 3 - acrylic acid.Nitrile gloves can offer some protection against furan -3 - acrylic acids. This helps prevent skin irritation, which could potentially occur if the acid comes into direct contact with the skin.This can help prevent skin irritation that could occur if the acid is in direct contact with your skin. Skin exposure might lead to redness, itching, or even chemical burns in severe cases.Skin exposure can cause redness, itchiness, or even chemical burning in severe cases.

Secondly, eye protection is crucial.Second, eye protection is essential. Safety goggles or a face shield should be worn.Wear safety goggles or face shields. If the acid splashes into the eyes, it can cause serious damage, including corneal abrasions and long - term vision problems.If the acid splashes in the eyes, serious damage can occur, including corneal erosions and long-term vision problems. By wearing proper eye protection, the risk of such injuries is significantly reduced.Wearing eye protection can reduce the risk of injury.

In terms of respiratory protection, in areas with poor ventilation or when there is a potential for the formation of dust or vapors of furan - 3 - acrylic acid, a respirator should be used.A respirator is recommended for respiratory protection in areas with poor ventilation, or when there's a possibility of dust or vapors forming from furan -3 - acrylic acids. Although furan - 3 - acrylic acid may not be highly volatile under normal conditions, fine dust particles could be inhaled, which might irritate the respiratory tract.Furan - 3 acrylic acid is not volatile in normal conditions. However, fine dust particles can be inhaled and cause irritation to the respiratory tract. Prolonged or high - level inhalation could potentially lead to more serious respiratory issues.Inhalation of high or prolonged levels could lead to respiratory problems.

When storing furan - 3 - acrylic acid, it should be kept in a cool, dry place away from sources of ignition.Furan - 3 acrylic acid should be stored in a cool and dry place, away from sources that can ignite. Although it is not highly flammable, like many organic compounds, it can still pose a fire risk if exposed to high heat or flames.It is not highly flammable like many organic compounds but it can still cause a fire if exposed to heat or flames. It should also be stored separately from strong oxidizing agents and bases.It should be stored away from bases and strong oxidizing agents. Contact with oxidizing agents could potentially lead to violent reactions, while reaction with bases could result in the formation of salts and other products, which might be difficult to handle or could have unexpected properties.Contact with oxidizing substances can cause violent reactions. Reactions with bases can result in salts or other products that are difficult to handle, or have unexpected properties.

During the handling process, ensure that the work area is clean and well - organized.Ensure that the work area remains clean and well-organized during the handling process. Spills should be cleaned up immediately.Spills must be cleaned immediately. In case of a spill, first, put on additional PPE if necessary.If necessary, wear additional PPE in the event of a spill. Then, carefully contain the spill using absorbent materials such as sand or vermiculite.Contain the spill carefully using absorbent materials like sand or Vermiculite. The contaminated absorbent should be disposed of properly according to local environmental regulations.The contaminated absorbent must be disposed of according to local environmental regulations.

Finally, it is important to be familiar with the first - aid procedures in case of an accident.It is also important to know how to administer first aid in the event of an accident. In case of skin contact, immediately flush the affected area with plenty of water for at least 15 minutes and seek medical attention if irritation persists.If you have skin contact, flush the area with water for at least fifteen minutes. Seek medical attention if irritation continues. For eye contact, rinse the eyes thoroughly with running water for an extended period and consult a doctor.If you have eye contact, wash your eyes with plenty of water and for a long time. Consult a doctor. If inhaled, move to fresh air and seek medical help if breathing difficulties occur.If inhaled move to fresh air if breathing problems occur.

Is furan-3-acrylic acid soluble in water?

Furan - 3 - acrylic acid is a compound with a furan ring and an acrylic acid moiety.Furan - 3 acrylic acid is a mixture of a furan ring with an acrylic acid moiety. Solubility in water depends on several factors.Solubility in aqueous solution depends on a number of factors.
First, consider the polar groups in furan - 3 - acrylic acid.Consider first the polar groups of furan - 3- acrylic acid. The carboxylic acid group (-COOH) is highly polar.The carboxylic acid (-COOH), is a highly polar group. In water, the carboxylic acid group can form hydrogen bonds with water molecules.The carboxylic group can form hydrogen bond with water molecules in water. The oxygen atom of the carbonyl group in -COOH can act as a hydrogen - bond acceptor, and the acidic hydrogen can act as a hydrogen - bond donor.The oxygen atom in the carbonyl group of -COOH may act as a donor of hydrogen bonds, while the acidic hydrogen may act as an acceptor. This hydrogen - bonding interaction is a key factor that promotes solubility in water for many carboxylic - acid - containing compounds.This hydrogen – bonding interaction is the key factor that promotes water solubility for many carboxylic acid-containing compounds.

However, the furan ring part of furan - 3 - acrylic acid is non - polar.Furan - 3 acrylic acid, however, contains a non-polar furan ring. The furan ring is composed of carbon and hydrogen atoms in a cyclic structure, and these C - H bonds do not have a significant dipole moment.The furan ring consists of carbon and hydrogen in a cyclic arrangement. These C-H bonds do not have an important dipole moment. Non - polar groups tend to oppose solubility in water, which is a polar solvent.Non-polar groups tend to be incompatible with solubility when dissolved in water, a polar solvant. The non - polar nature of the furan ring creates a hydrophobic effect.The non-polar nature of furan rings creates a hydrophobic reaction. Hydrophobic molecules or parts of molecules tend to aggregate together to minimize their contact with water molecules, reducing the overall solubility of the compound.Hydrophobic molecules and parts of molecules tends to aggregate together in order to minimize their contact to water molecules. This reduces the overall solubility.

Overall, the solubility of furan - 3 - acrylic acid in water is relatively limited.Furan - 3 acrylic acid is relatively soluble in water. The balance between the polar carboxylic acid group that promotes solubility and the non - polar furan ring that inhibits solubility results in a situation where it is not highly soluble in water.The balance between the polar carboxylic group that promotes water solubility and non -polar furan ring which inhibits it results in a compound that is not highly soluble. While the carboxylic acid group can form some hydrogen bonds with water, the presence of the relatively large non - polar furan ring restricts the extent to which the compound can dissolve.The carboxylic acid can form hydrogen bonds with water but the presence of the non-polar furan ring, which is relatively large, limits the amount to which the compound will dissolve. It is likely to be only sparingly soluble in water, meaning that only a small amount of furan - 3 - acrylic acid will dissolve in a given volume of water at a particular temperature.It is only sparingly water soluble, meaning that a small amount will dissolve in a certain volume of water when the temperature is a certain. Temperature can also affect its solubility.Temperature can affect its solubility. Generally, an increase in temperature might increase the solubility slightly as it provides more energy to overcome the hydrophobic interactions of the furan ring and allow more of the compound to interact with water molecules through the carboxylic acid group.In general, an increase in temperatures can increase its solubility as it gives more energy to overcome hydrophobic interactions between the furan ring. This allows more of the compound's carboxylic acid to interact with the water molecules. But overall, due to the presence of the non - polar furan ring, furan - 3 - acrylic acid is not considered highly soluble in water.Furan - 3 acrylic acid is not highly soluble in the water due to its non-polar furan ring.