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Furylacrylic Acid


Properties
Product Name Furylacrylic acid
Cas Number 623-43-8
Formula C7H6O3
Molar Mass 138.12 g/mol
Property 1 Density: 1.34 g/cm³
Property 2 Melting Point: 172-175°C
Property 3 Boiling Point: 295°C at 760 mmHg
Property 4 Flash Point: 133.1°C
Property 5 Solubility in Water: Slightly soluble
Property 6 Appearance: White to light yellow crystalline powder
Property 7 Odor: Characteristic
Property 8 pKa: 3.55
Property 9 Refractive Index: 1.572
Property 10 LogP: 1.28
FAQ

What is furylacrylic acid used for?

Furylacrylic acid, also known as 3-(2-furyl)acrylic acid, has several important applications.Furylacrylic Acid, also known by the name 3-(2-furyl-acrylic acid), has many important applications.
In the field of pharmaceuticals, furylacrylic acid derivatives can be synthesized and used as potential drug candidates.In the pharmaceutical industry, furylacrylic acids can be synthesized as drug candidates. Some of these derivatives have shown antibacterial, antifungal, and anti - inflammatory properties.Some of these derivatives show antibacterial, antifungal and anti-inflammatory properties. For example, certain chemical modifications of furylacrylic acid can lead to compounds that target specific enzymes or cellular pathways involved in the pathogenesis of infectious diseases.Furylacrylic acid, for example, can be modified chemically to produce compounds that target specific enzymes and cellular pathways involved in infectious disease pathogenesis. These derivatives can interact with the biological macromolecules in bacteria or fungi, inhibiting their growth and reproduction.These derivatives can interact and inhibit the growth of bacteria or fungi by interfering with their biological macromolecules. In the case of anti - inflammatory applications, they may interfere with the production of pro - inflammatory cytokines in the body, thus helping to alleviate inflammatory conditions.In the case anti-inflammatory applications, these derivatives may interfere with the body's production of pro-inflammatory cytokines, helping to alleviate inflammation conditions.

It is also utilized in the fragrance and flavor industry.It is also used in the fragrance and flavor industries. Furylacrylic acid and its esters possess pleasant odors.Furylacrylic acids and their esters have pleasant smells. They can be used to create unique and appealing scents in perfumes, air fresheners, and other fragrance - based products.They can be used in perfumes, air-fresheners, and other scent-based products to create unique and attractive scents. In the flavor aspect, they can contribute to the development of flavors in food and beverages.They can also contribute to the development and enhancement of flavors in foods and beverages. For instance, they might be added in small amounts to enhance the fruity or floral undertones in certain products, adding an extra layer of complexity to the taste profile.They can be added in small quantities to enhance the floral or fruity undertones of certain products. This will add an extra layer to the taste profile.

In the realm of organic synthesis, furylacrylic acid serves as a valuable building block.Furylacrylic acid is a useful building block in organic synthesis. Its unsaturated double bond and the furan ring make it a reactive molecule.Its double bond is unsaturated and its furan ring makes it a highly reactive molecule. Chemists can perform various chemical reactions on it, such as addition reactions, condensation reactions, and cycloaddition reactions.It can be subjected to a variety of chemical reactions such as addition reactions and condensation reactions. These reactions allow the creation of more complex organic compounds with diverse structures and properties.These reactions can create more complex organic compounds that have diverse properties and structures. These synthesized compounds can then be further used in different industries, from materials science to the production of specialty chemicals.These compounds can be used in a variety of industries, from materials to specialty chemicals.

In the production of polymers, furylacrylic acid can be incorporated into polymer structures.Furylacrylic acid is a component that can be used in the production of polymers. By copolymerizing furylacrylic acid with other monomers, polymers with unique properties can be obtained.Polymers with unique properties are obtained by copolymerizing the furylacrylic acids with other monomers. These polymers may have enhanced solubility, improved mechanical properties, or specific chemical reactivity due to the presence of the furyl and acrylic acid moieties.These polymers can have improved solubility, mechanical properties, or a specific chemical reactivity because of the presences of furyl and acrylic acids. This can expand the range of applications of these polymers in areas such as coatings, adhesives, and biodegradable materials.This can increase the range of applications for these polymers, such as in coatings, adhesives and biodegradable material.

Overall, furylacrylic acid plays a significant role in multiple industries, contributing to the development of new drugs, enhancing the sensory experiences in fragrance and flavor products, enabling the synthesis of complex organic compounds, and modifying the properties of polymers for various applications.Furylacrylic acid is used in a wide range of industries. It contributes to the development of new drugs and enhances the sensory experience of fragrances and flavor products. It also allows the synthesis and modification of polymers.

Is furylacrylic acid harmful to humans?

Furylacrylic acid can have both potential benefits and potential harmful aspects to humans, depending on the context.Furylacrylic acid has both potential benefits and potential harm to humans depending on context.
Furylacrylic acid is a compound that has been studied for its various properties.Furylacrylic Acid is a compound whose properties have been studied. In some cases, it has shown certain biological activities that could be beneficial.In some cases it has shown biological activities that may be beneficial. For example, it has been investigated for its possible antibacterial and antifungal properties.It has been studied for its antibacterial and antifungal qualities. These properties might be harnessed in the development of natural preservatives or in treating certain microbial - related conditions.These properties could be used to develop natural preservatives and treat certain microbial-related conditions.

However, there are also concerns regarding its potential harm.There are concerns about its potential harm. When it comes to direct human exposure, if inhaled in large amounts, it could potentially irritate the respiratory tract.Inhaling large amounts of furylacrylic acid could potentially irritate respiratory tracts when it comes to direct exposure. The fine particles of furylacrylic acid, if present in high concentrations in the air, may cause coughing, shortness of breath, and other respiratory discomforts.If high concentrations of furylacrylic acids are present in the air, they can cause coughing, shortness in breath, and other respiratory discomforts.

Skin contact can also be an issue.Skin contact can be a problem. It might cause skin irritation, especially in individuals with sensitive skin.It can cause skin irritation in people with sensitive skin. Prolonged or repeated contact could lead to redness, itching, and in more severe cases, skin lesions.Contact that is repeated or prolonged can cause skin irritation, including redness, itching and, in severe cases, lesions.

If ingested, furylacrylic acid may have effects on the digestive system.Furylacrylic Acid can have adverse effects on the digestive tract if ingested. It could potentially cause stomach upset, nausea, vomiting, and diarrhea.It may cause nausea, vomiting and diarrhea. The compound may interact with the normal functioning of the digestive enzymes and disrupt the digestive process.The compound could interfere with the normal function of digestive enzymes, disrupting the digestive process.

Moreover, long - term exposure to furylacrylic acid, even in low levels, might have cumulative effects.Even low-level exposure to furylacrylic acids over a long period of time could have cumulative effects. There is a lack of comprehensive long - term human studies, but based on animal studies and knowledge of similar compounds, it is possible that continuous exposure could impact the liver and kidneys, which are responsible for filtering and eliminating foreign substances from the body.Although there are no long-term human studies, animal studies and the knowledge of similar compounds suggest that a continuous exposure to furylacrylic acid could have an impact on the liver and kidneys. These organs are responsible for filtering out foreign substances.

In conclusion, while furylacrylic acid has some potentially useful properties, it is important to handle it with care.Furylacrylic Acid has some potential useful properties. However, it must be handled with care. Appropriate safety measures should be taken to avoid inhalation, skin contact, and ingestion to prevent potential harmful effects on human health.To prevent harmful effects to human health, it is important to take appropriate safety measures to avoid inhalation and skin contact.

How is furylacrylic acid synthesized?

Furylacrylic acid can be synthesized through several methods, with the Knoevenagel condensation being a common approach.Furylacrylic Acid can be synthesized in several ways, the Knoevenagel Condensation being one of them. Here is a general description of its synthesis.Here is a description of its general synthesis.
The reaction typically involves furfural and malonic acid as the main starting materials.Furfural and malonic acids are the two main starting materials in this reaction. Furfural is an aldehyde derived from biomass - based sources, and malonic acid contains two carboxylic acid groups.Furfural, an aldehyde that is derived from biomass-based sources, contains two carboxylic acids.

In the presence of a base catalyst, such as pyridine or piperidine, the reaction proceeds.The reaction proceeds in the presence of a catalyst, such a pyridine or a piperidine. The base first deprotonates malonic acid, generating a carbanion.The base deprotonates the malonic acid first, generating carbanion. This carbanion is highly reactive and attacks the carbonyl carbon of furfural.This carbanion attacks the carbonyl of furfural. The carbonyl group of furfural is polarized, with the carbon atom being electrophilic.The carbonyl group in furfural is polarized and the carbon atom is electrophilic. The addition of the carbanion to the carbonyl carbon forms an intermediate.The carbanion is added to the carbonyl atom of furfural to form an intermediate.

Subsequently, a series of intramolecular rearrangements and eliminations occur.Subsequently a series intramolecular rearrangements occur. A water molecule is eliminated, and the double bond is formed between the carbon atoms adjacent to the furyl ring and the remaining part of the molecule, leading to the formation of furylacrylic acid.A water molecule gets eliminated and a double bond forms between the carbon atoms next to the furyl ring, and the rest of the molecule. This leads to the formation furylacrylic acids.

The reaction is usually carried out in a suitable solvent.Solvents like ethanol or toluene can be used. Solvents like ethanol or toluene can be used.Solvents such as ethanol or toluene are suitable. The choice of solvent affects the reaction rate and the solubility of the reactants and products.The choice of solvent can affect the reaction rate and solubility of reactants and products. Ethanol, for example, is a polar solvent that can enhance the interaction between the reactants and the catalyst.Ethanol is a polar solvant that can enhance the interaction of the reactants with the catalyst.

After the reaction is complete, the product can be isolated through purification techniques.Purification techniques can be used to isolate the product after the reaction has been completed. One common method is recrystallization.Recrystallization is a common method. The reaction mixture is first cooled, and the furylacrylic acid may precipitate out.The reaction mixture must be cooled first, and the furylacrylic may precipitate. The crude product can be dissolved in a minimum amount of a hot suitable solvent, such as ethanol - water mixture.The crude product may be dissolved with a small amount of a suitable hot solvent, such as an ethanol-water mixture. As the solution cools, pure furylacrylic acid crystallizes out, leaving impurities in the solution.As the solution cools down, the pure furylacrylic crystallizes, leaving the impurities behind. Filtration can then be used to collect the pure crystals of furylacrylic acid.Filtration is then used to collect pure crystals of furylacrylic.

Another aspect to consider is the reaction conditions.The conditions of the reaction are also important. The reaction temperature is an important factor.The reaction temperature is a key factor. Generally, the reaction is carried out at a moderate temperature, usually around 80 - 120 degC.The reaction is usually carried out at a moderately high temperature, typically between 80 and 120 degC. Higher temperatures may lead to side reactions, while lower temperatures may slow down the reaction rate significantly.High temperatures can cause side reactions while low temperatures can slow down the rate of reaction. Also, the reaction time needs to be optimized.The reaction time must also be optimized. Too short a reaction time may result in incomplete conversion of the reactants, while an overly long reaction time may cause degradation of the product or formation of more by - products.A reaction time that is too short can result in an incomplete conversion of the reactants. On the other hand, a reaction speed that is too long may lead to degradation of the product and the formation of more by-products.

In conclusion, the synthesis of furylacrylic acid via Knoevenagel condensation is a well - established method, but careful control of reaction conditions and proper purification steps are essential to obtain high - quality product.In conclusion, the synthesis is furylacrylic via Knoevenagel condensing. However, careful control of the reaction conditions and proper purification are essential for obtaining high-quality product.

What are the properties of furylacrylic acid?

Furylacrylic acid, also known as 3 - (2 - furyl)acrylic acid, has several important properties.Furylacrylic Acid, also known by the name 3 - (2- furyl)acrylic acids, has a number of important properties.
Physical properties:Physical Properties
It exists as a white to light - yellow crystalline powder.It is a white or light-yellow crystalline powder. Furylacrylic acid has a characteristic melting point, typically in the range of around 139 - 141 degC.Furylacrylic Acid has a characteristic melting temperature, usually in the range 139-141 degC. This melting point is a key identifier for the compound and is useful in quality control and purification processes.This melting point is used to identify the compound, and is helpful in quality control and purification procedures. In terms of solubility, it has limited solubility in water.It has a limited solubility when it comes to water. However, it shows better solubility in some organic solvents such as ethanol, methanol, and acetone.It is more soluble in organic solvents like acetone, methanol and ethanol. This solubility behavior is related to the polar - nonpolar nature of the molecule.This solubility is related to the polar-nonpolar nature of the molecular structure. The furan ring is relatively non - polar, while the carboxylic acid group is polar.The carboxylic acid group, however, is polar. The balance between these two moieties determines its solubility characteristics.The balance between the two moieties determines the solubility.

Chemical properties:Chemical properties
The carboxylic acid group in furylacrylic acid is highly reactive.The carboxylic acid group of furylacrylic acids is highly reactive. It can participate in typical acid - base reactions.It can participate in acid-base reactions. For example, it can react with bases such as sodium hydroxide to form the corresponding carboxylate salt.It can, for example, react with bases like sodium hydroxide in order to form the carboxylate salt. This property is useful in the synthesis of derivatives and in the separation and purification of the compound.This property is helpful in the synthesis and separation of derivatives, as well as in the purification and separation of the compound. The double bond in the acrylic acid part of the molecule also endows it with reactivity.The double bond of the acrylic acid portion of the molecule gives it reactivity. It can undergo addition reactions, such as with bromine to form a dibromo - derivative.It can undergo addition reaction, such as with Bromine to form dibromo-derivative. This double - bond reactivity can be exploited in the synthesis of more complex organic molecules.This double-bond reactivity can also be used to synthesize more complex organic molecules. Additionally, the furan ring can also participate in certain electrophilic aromatic substitution reactions.The furan ring is also capable of participating in certain electrophilic aromatic substitute reactions. The electron - rich nature of the furan ring makes it susceptible to attack by electrophiles, although the reactivity may be modified by the presence of the acrylic acid side - chain.The furan ring is susceptible to electrophile attack due to its electron-rich nature. However, the reactivity can be modified by the presence the side-chain of acrylic acid.

Biological properties:Biological properties
Furylacrylic acid has shown some biological activities in certain studies.In certain studies, furylacrylic acid showed some biological activity. It has been reported to possess antibacterial properties against some common bacteria.It has been reported that it has antibacterial properties. This antibacterial activity may be related to its ability to interact with the cell membranes or metabolic pathways of the bacteria.This antibacterial activity could be related to the ability of the product to interact with cell membranes or metabolic pathway of the bacteria. It also has potential antioxidant properties.It may also have antioxidant properties. The conjugated system in the molecule, which includes the double bond and the furan ring, can act as a scavenger of free radicals.The double bond and furan ring in the conjugated system of the molecule can act as a scavenger for free radicals. These biological properties make it a compound of interest in the fields of medicine, food preservation, and cosmetics.These biological properties make this compound a compound of great interest in the fields such as medicine, food preservation and cosmetics.

In conclusion, furylacrylic acid has a combination of physical, chemical, and biological properties that make it valuable in various chemical and biological applications.Furylacrylic acid is a mixture of physical, chemical and biological properties. This combination makes it useful in a variety of chemical and biological applications. Its physical properties govern its handling and processing, while its chemical properties are the basis for its use in organic synthesis, and its biological properties open up possibilities in the life - science - related industries.Its physical properties determine its handling and processing. Its chemical properties allow it to be used in organic synthesis. And its biological properties offer new possibilities in life-science-related industries.

Where can furylacrylic acid be found?

Furylacrylic acid can be found in several places.Furylacrylic acids can be found in many places.
In nature, it may occur in some plants.It may be found in nature. Some plant species produce various organic compounds as part of their secondary metabolism, and furylacrylic acid could potentially be one of them.Furylacrylic acid is one of the organic compounds that some plant species produce as part of their second metabolism. However, its natural occurrence is not extremely widespread and may be limited to certain plant families or specific ecological niches.It is not widespread in nature and may only be found in certain plant families or ecological niches. These plants might use such compounds for defense mechanisms against pests, or as part of their chemical signaling processes.These plants may use these compounds as defense mechanisms against pests or as part their chemical signaling process.

In the laboratory, furylacrylic acid is a synthetically accessible compound.Furylacrylic acid can be synthesized in the laboratory. Chemists can prepare it through a variety of chemical reactions.It can be prepared by chemists through a variety if chemical reactions. One common method is via condensation reactions, often starting from furfural and appropriate aldehydes or ketones under specific reaction conditions.A common method is condensation reactions. This usually starts with furfural, and then appropriate aldehydes and ketones are added under specific conditions. These synthetic routes allow for the controlled production of furylacrylic acid with desired purity levels.These synthetic routes allow the controlled production of furylacrylic acids with desired purity levels. Laboratories that focus on organic synthesis, whether in academic research institutions or in the R & D departments of chemical companies, may be actively involved in its production.It can be produced in laboratories that specialize in organic synthesis. These may be in academic research institutions, or R & D departments in chemical companies.

Industrially, furylacrylic acid can be found in the supply chains related to the production of certain chemicals.In the chemical industry, furylacrylic acids are found in supply chains that relate to the production of some chemicals. It serves as an important intermediate in the synthesis of a range of products.It is an important intermediate used in the synthesis for a variety of products. For example, it can be used in the production of pharmaceuticals.It can be used to produce pharmaceuticals, for example. Some drugs or drug candidates may have furylacrylic acid as a key building block in their molecular structure.Furylacrylic acid may be a key component of the molecular structure of some drugs or drug candidates. Additionally, it can be utilized in the manufacturing of dyes.It can also be used to make dyes. The unique chemical structure of furylacrylic acid can contribute to the color - forming and light - absorbing properties of dyes, making it a valuable component in the dye - making industry.Furylacrylic Acid's unique chemical structure can contribute to the color-forming and light-absorbing properties of dyes. This makes it a valuable component for the dye-making industry. Chemical manufacturers that specialize in producing fine chemicals and intermediates are likely to have furylacrylic acid in their product portfolios, either for direct sale to other industries or for further in - house processing into more complex products.Furylacrylic Acid is likely to be in the product portfolios of chemical manufacturers who specialize in producing intermediates and fine chemicals. This acid can then be sold to other industries, or further processed in-house to produce more complex products.