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Product Name | Methacrylic acid 2-hydroxyethyl ester |
Cas Number | 868-77-9 |
Formula | C6H10O3 |
Molar Mass | 130.14 g/mol |
Boiling Point | 213 °C |
Density | 1.053 g/cm³ |
Flash Point | 101 °C |
Refractive Index | 1.452 at 20 °C |
Vapor Pressure | 0.15 mmHg at 20 °C |
Viscosity | 5.8 mPa·s at 20 °C |
Solubility In Water | Partially soluble |
Melting Point | -10 °C |
Appearance | Colorless liquid |
Autoignition Temperature | 435 °C |
What are the main applications of Methacrylic acid 2-hydroxyethyl ester?
Methacrylic acid 2 - hydroxyethyl ester, abbreviated as HEMA, has a wide range of applications.HEMA (Hydroxyethyl Ester) is a shorthand for Methacrylic Acid 2 - Hydroxyethyl Ester. It has many applications.
One of the significant applications is in the field of coatings.Coatings are a significant application. HEMA can be incorporated into coating formulations.HEMA can be included in coating formulations. Its hydroxyl group allows for cross - linking reactions, which can improve the hardness, abrasion resistance, and chemical resistance of the coatings.Its hydroxyl groups allow for cross-linking reactions which can improve coatings' hardness, abrasion and chemical resistance. For example, in automotive coatings, it helps to create a durable finish that can withstand various environmental conditions, such as exposure to sunlight, rain, and road debris.In automotive coatings, for example, it can help create a durable finish which can withstand different environmental conditions such as exposure sunlight, rain and road debris. In industrial coatings, it can protect metal surfaces from corrosion and wear, thereby extending the lifespan of machinery and equipment.In industrial coatings it can protect metal surfaces against corrosion and wear. This extends the life of machinery and equipment.
HEMA is also crucial in the production of adhesives.HEMA is also important in the production and use of adhesives. The reactive groups in HEMA enable it to bond well with different substrates.HEMA's reactive groups allow it to bond with different substrates. It can be used in formulating pressure - sensitive adhesives that are used in applications like label - making.It can be used to formulate pressure-sensitive adhesives for applications such as label-making. These adhesives need to adhere firmly to surfaces but also be removable without leaving residue.These adhesives must adhere firmly to surfaces, but be removable without leaving residue. HEMA - based adhesives can provide the right balance of tack, peel strength, and shear strength to meet these requirements.HEMA-based adhesives are able to provide the perfect balance of tackiness, peel strength and shear strength in order to meet these demands. In addition, in structural adhesives, HEMA contributes to the formation of strong bonds between materials, such as in the assembly of composite materials used in aerospace and construction industries.HEMA also contributes to the formation strong bonds between materials in structural adhesives. This is especially true in the assembly composite materials used by the aerospace and construction industries.
In the area of dental materials, HEMA plays a vital role.HEMA is a key component in dental materials. It is a key component in dental resins.It is a major component of dental resins. Dental fillings made with HEMA - containing resins can bond well to tooth structure, providing good aesthetic results and long - lasting restoration.HEMA-containing resins are able to bond well with tooth structure and provide long-lasting restoration. The hydroxyl group in HEMA can interact with the hydroxyapatite in teeth, enhancing the adhesion.HEMA's hydroxyl group can interact with hydroxyapatite to enhance adhesion. Moreover, HEMA is used in dental impression materials.HEMA is also used in dental impression material. These materials need to be flexible during impression taking and then set to a stable form.These materials must be flexible when taking impressions and then set into a stable form. HEMA helps to achieve the proper rheological properties and setting characteristics for accurate dental impressions.HEMA helps achieve the correct rheological characteristics and setting properties for accurate dental impressions.
Another important application is in the production of contact lenses.Contact lenses are another important application. HEMA is a common monomer used in making hydrogel contact lenses.HEMA is used to make hydrogel contact lenses. Its hydrophilic nature allows the lenses to absorb water, which is essential for maintaining the health and comfort of the eyes.Hydrophilic lenses absorb water to maintain eye health and comfort. The cross - linked HEMA - based hydrogels can provide the necessary mechanical strength and optical clarity for the lenses, enabling clear vision while keeping the eyes moist.The HEMA-based hydrogels that are cross-linked can provide the necessary mechanical and optical strength for the lenses. This allows clear vision, while keeping the eye moist.
In the field of polymers and plastics, HEMA can be copolymerized with other monomers.HEMA can be polymerized with other monomers in the field of plastics and polymers. This copolymerization can modify the properties of the resulting polymers.This copolymerization may alter the properties of the polymers. For example, by copolymerizing HEMA with methyl methacrylate, polymers with improved impact resistance and optical properties can be obtained.By copolymerizing HEMA and methyl methacrylate for example, polymers can be produced with improved optical properties and impact resistance. These polymers can be used in various applications, such as in the production of optical lenses, light - emitting diode (LED) encapsulants, and plastic sheets for display applications.These polymers are suitable for a variety of applications, including the production optical lenses, LED encapsulants and plastic sheets used in display applications.
What are the properties of Methacrylic acid 2-hydroxyethyl ester?
Methacrylic acid 2 - hydroxyethyl ester, also known as HEMA, has several important properties.HEMA (also known as Methacrylic Acid 2 - Hydroxyethyl Ester) has many important properties.
Physical properties:Physical Properties
It is a colorless, clear liquid at room temperature.At room temperature, it is a clear, colorless liquid. It has a characteristic odor.It has a distinctive odor. HEMA has a relatively low viscosity, which allows it to flow easily.HEMA is relatively low in viscosity and flows easily. This property is beneficial in applications such as coatings and adhesives, where good flow and spreading characteristics are required.This property is useful in applications like coatings and adhesions where good flow and spread characteristics are needed. Its boiling point is around 189 - 195degC, which makes it suitable for processes that involve heating to moderate temperatures without excessive evaporation loss.Its boiling temperature is between 189 and 195degC. This makes it suitable for processes involving heating to moderate temperatures, without excessive evaporation.
Chemical properties:Chemical properties
HEMA contains both a hydroxyl (-OH) group and a methacrylate double bond.HEMA contains a methacrylate (-OH) double bond as well as a hydroxyl group. The methacrylate double bond is highly reactive.The double bond of the methacrylate is highly reactive. It can undergo polymerization reactions, either by free - radical polymerization or other polymerization mechanisms.It can undergo polymerization by free-radical polymerization, or other polymerization methods. This reactivity is the basis for its use in the production of a wide range of polymers.This reactivity is what makes it so useful in the production of many polymers. For example, in the manufacture of dental polymers, the double bond polymerizes to form a hard and durable structure.In the manufacture of dental materials, for example, the double bonds polymerize to form a durable and hard structure. The hydroxyl group in HEMA imparts hydrophilicity to the molecule.The hydroxyl group of HEMA confers hydrophilicity on the molecule. This means it has an affinity for water.It has an affinity towards water. In contact lens materials, this property allows the lenses to retain moisture, making them more comfortable to wear.This property is used in contact lens materials to allow lenses to retain moisture and be more comfortable. It can also participate in chemical reactions such as esterification and etherification.It can also be involved in chemical reactions like esterification and the etherification. For instance, the hydroxyl group can react with carboxylic acids to form esters, which can be used to modify the properties of the resulting polymers.The hydroxyl group, for example, can react with carboxylic acid to form esters. These esters can be used to modify properties of the polymers resulting from the reaction.
Polymerization - related properties:Polymerization and related properties
When polymerized, HEMA forms polymers with good mechanical properties.HEMA polymerizes to form polymers with excellent mechanical properties. The resulting polymers can be tailored to have different degrees of hardness, flexibility, and toughness depending on the polymerization conditions and the presence of other monomers.Polymers resulting from HEMA polymerization can be tailored for different degrees of toughness, flexibility and hardness depending on polymerization conditions. The polymers formed from HEMA also have good optical clarity.Polymers made from HEMA have a good optical clarity. This is crucial in applications like optical lenses, where high transparency is required.This is important for applications such as optical lenses where high transparency is needed. Additionally, the polymers have good chemical resistance.The polymers are also chemically resistant. They can withstand exposure to a variety of chemicals, which is useful in industrial coatings and protective films.They can withstand exposure of a variety chemicals, which makes them useful for industrial coatings and protective film.
Biocompatibility:
HEMA is considered to have good biocompatibility.HEMA is considered biocompatible. This property makes it suitable for use in medical applications.This property makes HEMA suitable for medical applications. In the field of tissue engineering, polymers made from HEMA can be used as scaffolds to support cell growth.Polymers made from HEMA are used in tissue engineering as scaffolds that support cell growth. Its ability to interact well with biological systems without causing significant adverse reactions is an important advantage.Its ability to interact with biological systems without causing adverse reactions is a major advantage. However, in some cases, individual sensitivity to HEMA can occur, especially in the form of contact dermatitis when it comes into direct contact with the skin.HEMA can cause individual sensitivity in some cases. This is most common in contact dermatitis, which occurs when the HEMA comes into contact with the skin. But overall, with proper formulation and use, its biocompatibility allows for its widespread use in medical - related products.Biocompatibility is a major factor in the use of HEMA in medical-related products.
How is Methacrylic acid 2-hydroxyethyl ester synthesized?
Methacrylic acid 2 - hydroxyethyl ester is typically synthesized through an esterification reaction.Esterification is the most common way to synthesize Methacrylic Acid 2 - Hydroxyethyl Ester.
The main starting materials are methacrylic acid and ethylene oxide or 2 - chloroethanol.Methacrylic acid, ethylene oxide and 2 - chloroethanol are the main starting materials. When using ethylene oxide:
1. Reaction conditions: The reaction between methacrylic acid and ethylene oxide is usually carried out in the presence of a catalyst.Conditions of reaction: The reaction between ethylene oxide and methacrylic acids is usually carried out with the presence a catalyst. Commonly used catalysts include tertiary amines such as triethylamine or metal salts like zinc acetate.Catalysts are commonly used tertiary amino acids such as triethylamine, or metal salts such zinc acetate. The reaction is exothermic, so temperature control is crucial.Temperature control is important because the reaction is exothermic. It is often conducted at a relatively moderate temperature, typically in the range of 60 - 100 degC.The reaction is usually conducted at a moderate temperature, usually between 60 and 100 degC.
2. Reaction mechanism: Methacrylic acid contains a carboxylic acid group (-COOH), and ethylene oxide has a highly reactive epoxide ring.Reaction mechanism: Methacrylic acids contain a carboxylic group (-COOH) and ethylene oxide contains a highly reactive, epoxide-ring. The lone pair of electrons on the oxygen atom of the carboxylic acid attacks one of the carbon atoms in the epoxide ring of ethylene oxide.The oxygen atom in the carboxylic acids attacks the carbon atom in the epoxide rings of ethylene oxide. This opens the epoxide ring, and a new carbon - oxygen bond is formed.This opens the epoxide and a new bond between carbon and oxygen is formed. The result is the attachment of the 2 - hydroxyethyl group to the methacrylic acid, forming methacrylic acid 2 - hydroxyethyl ester.The 2 -hydroxyethyl group is attached to the methacrylic acids, resulting in the 2 hydroxyethyl esters.
3. Purification: After the reaction, the product mixture may contain unreacted starting materials, by - products, and the catalyst.Purification: The product mixture after the reaction may contain unreacted materials, by-products, and the catalyst. Purification steps are necessary.Purification steps are required. One common method is distillation.Distillation is a common method. Due to the differences in boiling points of methacrylic acid 2 - hydroxyethyl ester, unreacted methacrylic acid, and other components, distillation can be used to separate and obtain the pure product.Distillation is a common method to separate the components.
When using 2 - chloroethanol:When using 2 – chloroethanol:
1. Reaction process: First, methacrylic acid reacts with a base such as sodium hydroxide to form the sodium salt of methacrylic acid.Process of reaction: Methacrylic acids react with a base, such as sodium hydroxide, to form sodium salts of methacrylic acids. Then, 2 - chloroethanol is added to this sodium salt.Then, the 2 - chloroethanol salt is added. The chlorine atom in 2 - chloroethanol is a good leaving group.The chlorine atom of 2 - chloroethanol acts as a good leaving group. The negatively charged oxygen in the sodium methacrylate attacks the carbon atom bonded to the chlorine in 2 - chloroethanol.The oxygen negatively charged in sodium methacrylate attacks 2 - chloroethanol's carbon atom. This substitution reaction leads to the formation of methacrylic acid 2 - hydroxyethyl ester.This substitution reaction results in the formation of 2 - hydroxyethyl esters.
2. Separation and purification: Similar to the previous method, after the reaction, separation techniques like filtration to remove salts formed during the reaction, followed by distillation to purify the product, are employed to obtain high - purity methacrylic acid 2 - hydroxyethyl ester.Separation and Purification: After the reaction, similar to the previous method are used separation techniques such as filtration to remove the salts formed during reaction, followed by distillation to purify product to obtain high-purity methacrylic 2 -hydroxyethyl ester. This synthesis method is important as the resulting ester is widely used in various industries such as coatings, adhesives, and polymers due to its ability to polymerize and form cross - linked structures.This method is important because the resulting ester can be used in many industries, including coatings, adhesives and polymers, due to its ability polymerize and create cross-linked structures.
What are the safety precautions when handling Methacrylic acid 2-hydroxyethyl ester?
Methacrylic acid 2 - hydroxyethyl ester is a chemical compound with certain reactivity and potential hazards.Methacrylic Acid 2 - Hydroxyethyl Ester is a chemical compound that has a certain level of reactivity. It also poses some potential hazards. When handling it, the following safety precautions should be taken.Safety precautions are necessary when handling this chemical compound.
First, personal protective equipment is essential.Wearing personal protective equipment (PPE) is crucial. Wear appropriate chemical - resistant gloves, such as those made of nitrile or neoprene.Wear gloves that are resistant to chemicals, such as those made from nitrile or Neoprene. These gloves can prevent the chemical from coming into direct contact with the skin, as skin contact may cause irritation, redness, and in severe cases, burns.These gloves will prevent the chemical from coming in direct contact with your skin. This can cause irritation, redness and, in severe cases, even burns. Also, wear safety goggles or a face shield.Wear safety goggles, or a face shield. This will protect the eyes from any splashes of the methacrylic acid 2 - hydroxyethyl ester.This will protect your eyes from any splashes or vapors of methacrylic 2 - hydroxyethyl ester. If it gets into the eyes, it can cause serious eye damage, including corneal burns and loss of vision.If it gets in the eyes, it could cause serious eye damage including corneal burning and loss of sight.
Second, ensure good ventilation in the handling area.Second, make sure that the area where you are handling the chemical is well ventilated. This chemical may release vapors, and if inhaled, it can irritate the respiratory tract, causing coughing, shortness of breath, and potentially more serious respiratory problems.Inhaling vapors from this chemical can cause irritation of the respiratory tract. This can lead to coughing, shortness breath, and even more serious respiratory problems. A well - ventilated area helps to dilute the vapors and reduce the risk of inhalation exposure.A well-ventilated area can help to dilute vapors, reducing the risk of inhalation. If possible, handle the substance in a fume hood, which can effectively capture and exhaust the vapors.If possible, use a fume-hood to capture and exhaust the vapors.
Third, be careful during storage.Third, take care when storing. Store methacrylic acid 2 - hydroxyethyl ester in a cool, dry place away from heat sources, flames, and oxidizing agents.Store methacrylic 2 - hydroxyethyl ester in a cool and dry place, away from heat sources, oxidizing agents, and flames. It is flammable, and high temperatures or contact with oxidizers can lead to fire or explosion hazards.It is flammable and contact with oxidizers or high temperatures can cause fire or explosion hazards. Keep the containers tightly sealed when not in use to prevent leakage and evaporation.Keep the containers tightly closed when not in use. This will prevent leakage and evaporation.
Fourth, in case of spills, act promptly.Act quickly in the event of spills. First, evacuate the area to prevent unnecessary exposure to others.To avoid unnecessary exposure, first evacuate the area. Then, use appropriate absorbent materials, like sand or vermiculite, to soak up the spill.Use absorbent materials like sand, vermiculite or sand to soak up the spill. Avoid using materials that may react with the chemical.Avoid materials that could react with the chemical. Dispose of the contaminated absorbent according to local regulations.Dispose of contaminated absorbents according to local regulations.
Finally, in case of contact with the skin or eyes, take immediate first - aid measures.In the event of contact with skin or eyes, you should take immediate first-aid measures. For skin contact, quickly rinse the affected area with plenty of water for at least 15 minutes.Rinse the affected area thoroughly with water for 15 minutes if it is skin contact. Remove any contaminated clothing during the rinsing process.Remove any contaminated clothing while rinsing. For eye contact, hold the eye open and rinse it gently with running water for at least 15 minutes, and then seek immediate medical attention.If you have eye contact, keep the eye open for 15 minutes and gently rinse it with running water. Then seek immediate medical attention. In case of inhalation, move the affected person to fresh air immediately and call for medical help if the person shows any signs of respiratory distress.In the case of inhalation of the substance, the affected person should be moved to fresh air as soon as possible. Call for medical assistance if they show signs of respiratory distress.
What are the storage requirements for Methacrylic acid 2-hydroxyethyl ester?
Methacrylic acid 2 - hydroxyethyl ester is a chemical compound with specific storage requirements to ensure its stability and safety.Methacrylic Acid 2 - Hydroxyethyl Ester is a chemical compound that has specific storage requirements for its safety and stability.
First, storage should be in a cool and well - ventilated area.Storage should be done in a well-ventilated, cool area. High temperatures can accelerate chemical reactions, such as polymerization.High temperatures can speed up chemical reactions such as polymerization. A recommended storage temperature range is typically between 2 - 8 degrees Celsius.The recommended temperature range for storage is usually between 2 and 8 degrees Celsius. This helps to slow down any potential self - reaction of the ester.This will help to slow down the potential self-reaction of the ester. If it is stored at too high a temperature, the risk of polymerization increases, which can lead to the formation of solid masses and render the product unusable.If the ester is stored at a high temperature, it increases the risk of polymerization, which can result in the formation of solid masses, rendering the product unusable.
Secondly, it must be stored away from sources of ignition.Second, it should be stored away form sources of ignition. Methacrylic acid 2 - hydroxyethyl ester is flammable.The flammable Methacrylic Acid 2 - Hydroxyethyl Ester. Any potential ignition sources like open flames, sparks from electrical equipment, or hot surfaces can cause a fire.A fire can be caused by any potential ignition source, such as open flames, sparks coming from electrical equipment or hot surfaces. In a storage facility, all electrical systems should be explosion - proof, and smoking should be strictly prohibited.In a storage area, all electrical equipment should be explosion-proof, and smoking must be strictly prohibited.
The storage containers also play a crucial role.The storage containers play an important role. They should be made of materials that are compatible with the chemical.The containers should be made from materials compatible with the chemical. Suitable materials include certain types of plastics and metals.Materials that are suitable include certain types plastics and metals. For example, some high - density polyethylene containers can be used as they do not react with the ester.Some high-density polyethylene containers, for example, can be used because they do not react to the ester. Metal containers, if used, need to be carefully selected to avoid corrosion.If metal containers are used, they must be carefully chosen to avoid corrosion. Corrosion can not only damage the container but also contaminate the product.Corrosion not only damages the container, but can also contaminate product.
The containers should be tightly sealed to prevent evaporation and contact with air.Containers should be tightly closed to prevent evaporation or contact with air. Exposure to air can lead to oxidation of the compound, which may change its chemical properties.Air exposure can cause oxidation, which could change the chemical properties of the compound. Additionally, moisture should be kept away.Moisture should also be kept at bay. Moisture can initiate hydrolysis reactions in the ester, breaking it down into its components and affecting its quality.Moisture can cause hydrolysis reactions, causing the ester to break down into its constituents and affect its quality.
Finally, when storing about 500 units (assuming volume or quantity), proper inventory management is essential.It is important to have a good inventory management system in place when storing 500 units. Regular checks should be carried out to monitor for any signs of leakage, changes in color or odor, which could indicate chemical degradation.Regular checks are needed to detect any signs of chemical degradation, such as color changes, odors, or leakage. In case of any issues, appropriate safety procedures should be followed to handle and dispose of the affected product safely.In the event of a problem, it is important to follow safety procedures in order to dispose of and handle the product safely.