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Hydroxyethyl Methacrylate(hema)


Properties
Product Name Hydroxyethyl methacrylate
Cas Number 868-77-9
Formula C6H10O3
Molar Mass 130.14 g/mol
Density 1.07 g/cm3
Boiling Point 213°C
Melting Point -12°C
Refractive Index 1.452
Viscosity 4.3 cP at 20°C
Flash Point 97°C
Solubility Miscible with water
Vapor Pressure 0.1 mmHg at 20°C
Appearance Clear liquid
Odor Estray-like odor
FAQ

What is the chemical structure of Hydroxyethyl Methacrylate (HEMA)?

Hydroxyethyl Methacrylate (HEMA) is an important monomer in polymer chemistry.Hydroxyethyl methacrylate is an important monomer for polymer chemistry. Its chemical formula is C6H10O3.Its chemical formula C6H10O3.
The chemical structure of HEMA consists of several key components.HEMA is composed of several key components. At its core, it has a methacrylate group.Its core is a methacrylate. The methacrylate part contains a carbon - carbon double bond (C=C) which is crucial for its polymerization ability.The methacrylate group contains a double carbon-carbon bond (C=C), which is critical for its polymerization capability. This double bond can react under appropriate conditions, such as in the presence of initiators, to form long - chain polymers.This double bond can react in certain conditions, like the presence of initiators to form long-chain polymers.

Attached to the methacrylate group is an ethyl group that has been hydroxylated.A hydroxylated ethyl group is attached to the methacrylate. Specifically, an ethylene glycol unit (-CH2CH2OH) is linked to the methacrylate.A ethylene glycol unit is attached to the methacrylate. The -OH group in the ethylene glycol part provides HEMA with certain properties.The -OH group of the ethylene glycol component gives HEMA certain properties. It can participate in hydrogen bonding, which affects the solubility and interaction of HEMA - based polymers with other substances.It can participate in hydrogen bonds, which affects solubility and interactions of HEMA-based polymers with different substances.

The general structure can be described as follows: Starting from the carbon - carbon double bond of the methacrylate, one of the carbon atoms of the double bond is attached to a methyl group (-CH3).The general structure is as follows: starting from the double carbon-carbon bond of the methacrylate (-CH3), one of its carbon atoms is attached to a group of methyl (-CH3). The other carbon of the double bond is part of a carbonyl group (C=O), which is then connected to an oxygen atom.The other carbon atom of the double-bond is part of a group called carbonyl (C=O), and is then connected to a oxygen atom. This oxygen atom is further linked to the ethylene glycol unit.This oxygen atom then links to the ethylene-glycol unit. The ethylene glycol unit has two carbon atoms in a linear arrangement, with the terminal carbon atom bearing the hydroxyl (-OH) group.The ethylene glycol has two carbon atoms arranged in a straight line, with the terminal carbon bearing the hydroxyl group (-OH).

HEMA's structure gives it a unique set of characteristics.The structure of HEMA gives it a unique collection of characteristics. The presence of the double bond enables it to polymerize and form cross - linked or linear polymers.The double bond allows it to polymerize, forming linear or cross-linked polymers. These polymers find applications in various fields.These polymers are used in many different fields. In the medical field, for example, due to its relatively good biocompatibility and the ability to form hydrogels when polymerized, it is used in contact lenses.It is used to make contact lenses in the medical field due to its biocompatibility. The -OH group in its structure contributes to the water - absorbing properties of these hydrogels, allowing the lenses to remain moist and comfortable on the eye.The -OH group contributes to its water-absorbing properties, allowing lenses to stay moist and comfortable. In coatings and adhesives, the polymerized form of HEMA can provide good adhesion and durability, taking advantage of the reactivity of the double bond during the curing process.The polymerized form HEMA is a good adhesive and can be durable in coatings and adhesions. It takes advantage of the reactivity and double bond during curing. Overall, the chemical structure of HEMA is the foundation for its wide - ranging applications in different industries.HEMA's chemical structure is the basis for its wide-ranging applications across different industries.

What are the main applications of HEMA?

HEMA, or 2 - Hydroxyethyl Methacrylate, has a wide range of applications due to its unique properties such as good biocompatibility, low toxicity, and the ability to polymerize.HEMA, or 2-Hydroxyethyl methacrylate, is a versatile material due to its unique properties, such as biocompatibility and low toxicity. It can also polymerize.
One of the major applications of HEMA is in the field of ophthalmology.HEMA has many applications in the field ophthalmology. It is a key component in the production of contact lenses.It is used as a component in the manufacture of contact lenses. Soft contact lenses are often made from hydrogels containing HEMA.Hydrogels containing HEMA are commonly used to make soft contact lenses. The hydrophilic nature of HEMA allows the lenses to absorb and retain water, which is crucial for maintaining the comfort and oxygen permeability of the contact lenses on the eye surface.The hydrophilic properties of HEMA allow the lenses to retain and absorb water, which is essential for maintaining comfort and oxygen permeability of the lenses on the eye surface. This helps to keep the eyes hydrated and reduces the risk of irritation and dryness.This helps keep the eyes hydrated, reducing the risk of irritation or dryness.

In the dental industry, HEMA is used in dental adhesives and composites.HEMA is used to make dental composites and adhesives. Dental adhesives need to bond well with tooth structures.Dental adhesives must bond well with tooth structure. HEMA can react with the functional groups present in the tooth surface, providing a strong and durable bond.HEMA can react to the functional groups on the surface of the tooth, forming a strong and lasting bond. In dental composites, which are used for filling cavities, HEMA helps in the polymerization process.HEMA is used in dental composites that are used to fill cavities. It enables the composite material to harden and set in place, restoring the tooth's structure and function.It allows the composite material hardening and setting in place to restore the tooth's function and structure.

HEMA also finds use in the area of biomedical engineering for making tissue - engineering scaffolds.HEMA is also used in biomedical engineering to make tissue-engineering scaffolds. These scaffolds are designed to support cell growth and tissue regeneration.These scaffolds support cell growth and regeneration of tissue. The biocompatibility of HEMA makes it suitable for this purpose.HEMA is biocompatible and therefore suitable for this application. Cells can attach, proliferate, and differentiate on HEMA - based scaffolds, promoting the formation of new tissues.HEMA-based scaffolds allow cells to attach, multiply, and differentiate, promoting the growth of new tissues. For example, in bone tissue engineering, HEMA - containing scaffolds can provide a three - dimensional structure for osteoblasts (bone - forming cells) to grow on, facilitating bone repair and regeneration.HEMA-containing scaffolds, for example, can provide a three-dimensional structure on which osteoblasts (bone-forming cells) can grow, facilitating bone regeneration and repair.

Another application is in the production of coatings.Another application is the production of coatings. HEMA can be incorporated into various coating formulations.HEMA can be included in various coating formulations. For instance, in automotive coatings, it can improve the hardness, scratch - resistance, and chemical resistance of the paint.In automotive paints, for example, it can increase the hardness, chemical resistance, and scratch-resistance of the paint. In industrial coatings, it helps to enhance the durability and performance of the coated surfaces, protecting them from environmental factors such as moisture, chemicals, and abrasion.In industrial coatings it can improve the durability and performance, protecting the surfaces from environmental factors like moisture, chemicals, abrasion, and abrasion.

In the field of cosmetics, HEMA can be used in some formulations.HEMA is used in cosmetic formulations. It can contribute to the texture and stability of products like nail polishes.It can improve the texture and stability in products such as nail polishes. In nail polishes, it helps the polish to adhere well to the nail surface and form a hard, shiny film.It helps nail polish adhere to the nail surface, forming a hard, glossy film.

Is HEMA harmful to human health?

HEMA, or 2 - Hydroxyethyl Methacrylate, is a monomer widely used in various industries, and its potential impact on human health is a topic of interest.HEMA or 2 - Hydroxyethyl methacrylate is a monomer that is widely used in many industries. Its potential impact on the human health is of great interest.
In general, direct contact with pure HEMA monomer can be harmful.Direct contact with pure HEMA can be harmful in general. It is a known skin and eye irritant.It is known to irritate the skin and eyes. When HEMA comes into contact with the skin, it can cause redness, itching, and in more severe cases, dermatitis.HEMA can cause skin irritation, rashes, itching and, in more severe cases dermatitis, when it comes into contact with your skin. This is because the monomer can penetrate the skin's outer layer and trigger an immune response.The monomer can penetrate skin's outer layer, triggering an immune response.

In the case of eye contact, HEMA can lead to significant discomfort, pain, and possible damage to the cornea.HEMA can cause significant discomfort and pain in the eyes, as well as possible corneal damage. Workers in industries where HEMA is used, such as in the production of dental materials and some types of plastics, are at a higher risk of such direct - contact exposures.Workers in industries that use HEMA, such as the production of dental materials or some types of plastics are at greater risk of direct-contact exposure.

Another concern is its potential for inhalation.Inhalation is another concern. In industrial settings where HEMA is processed and there may be vapor or aerosol formation, inhaling HEMA can irritate the respiratory tract.In industrial settings, where HEMA may be processed and aerosols or vapors are formed, inhaling HEMA could irritate respiratory tracts. Prolonged or high - level inhalation exposure may lead to more serious respiratory problems, although the exact long - term effects are still being studied.Inhaling HEMA at high levels or for long periods of time may cause respiratory problems. However, the exact long-term effects are still being investigated.

However, it's important to note that when HEMA is polymerized, its properties change significantly.It's important to know that HEMA's properties change dramatically when it is polymerized. In many consumer products like contact lenses, the polymerized form of HEMA is considered relatively safe.The polymerized HEMA is used in many consumer products, such as contact lenses. The polymerization process locks the HEMA monomers into a larger, more stable structure, reducing the likelihood of the individual monomers causing harm.The polymerization process locks HEMA monomers together into a larger and more stable structure. This reduces the likelihood that the monomers can cause harm.

In dental applications, once HEMA - based materials are cured into dental restorations or orthodontic appliances, they are generally well - tolerated by the oral cavity.Once HEMA-based materials are cured and used in dental applications such as orthodontic appliances or dental restorations, they are generally well-tolerated by the oral cavity. But during the dental procedure when the uncured HEMA - containing materials are being used, dental professionals and patients may be briefly exposed to the monomer.Dental professionals and patients can be exposed to monomer during dental procedures when HEMA-containing materials are used.

Overall, while HEMA in its monomer form has the potential to be harmful to human health, proper handling in industrial settings, and the use of polymerized HEMA in consumer products with appropriate safety measures, help to minimize these risks.HEMA monomer can be harmful to health. However, the proper handling of HEMA in industrial settings and the use polymerized HEMA as a consumer product with appropriate safety measures will help minimize these risks. Continued research is needed to fully understand the long - term and low - level exposure effects of HEMA on human health.HEMA's effects on human health at low and long-term levels will require further research.

How is HEMA synthesized?

HEMA, or 2 - Hydroxyethyl Methacrylate, is synthesized through several methods, with the most common being the reaction of methacrylic acid with ethylene oxide.HEMA, or 2-Hydroxyethyl methacrylate, can be synthesized in several ways, the most common of which is the reaction between methacrylic and ethylene oxide.
In this process, methacrylic acid serves as one of the key starting materials.Methacrylic acid is one of the main starting materials in this process. Methacrylic acid can be produced from the oxidation of isobutylene or the hydrolysis of methyl methacrylate.Methacrylic acids can be made by oxidizing isobutylene, or by hydrolyzing methyl methacrylate. Ethylene oxide is the other crucial reactant.The other important reactant is ethylene oxide. Ethylene oxide is typically derived from the oxidation of ethylene.Ethylene is usually converted to ethylene oxide through oxidation.

The reaction between methacrylic acid and ethylene oxide occurs in the presence of a catalyst.A catalyst is required to initiate the reaction between methacrylic and ethylene oxide. Commonly used catalysts include metal salts or tertiary amines.Catalysts are commonly used metal salts and tertiary amino acids. The reaction is an addition reaction, where the ethylene oxide molecule adds to the double - bond of the methacrylic acid.The reaction is an add-on reaction where the ethylene molecule adds on to the double – bond of the methacrylic acids. The oxygen atom in ethylene oxide forms a bond with the carbon atom of the double - bond in methacrylic acid, and the remaining part of the ethylene oxide molecule attaches to the adjacent carbon atom.The oxygen atom from ethylene oxide forms an atom with the carbon atom that is part of the double-bond in methacrylic acids, and the remainder of the ethylene molecule attaches itself to the adjacent carbon. This results in the formation of HEMA.HEMA is formed.

The reaction conditions need to be carefully controlled.The reaction conditions must be carefully controlled. The temperature is usually maintained within a certain range, typically around 60 - 100 degrees Celsius.Temperatures are usually kept within a certain range - typically between 60 and 100 degrees Celsius. If the temperature is too low, the reaction rate will be slow, and if it is too high, side reactions may occur.If the temperature is low, the reaction will be slow. If it is high, there may be side reactions. The pressure is often close to atmospheric pressure, although in some cases, slightly elevated pressures may be used to enhance the reaction rate.The pressure is usually close to atmospheric pressure. However, in some cases, slightly higher pressures can be used to increase the reaction rate.

After the reaction, the product mixture may contain unreacted starting materials, by - products, and the desired HEMA.After the reaction the product mixture can contain unreacted materials, by-products, and the desired HEMA. Purification steps are then necessary.Then, purification steps are required. These purification steps can include techniques such as distillation.Purification techniques can include distillation. HEMA has a specific boiling point, and by carefully controlling the distillation conditions, HEMA can be separated from other components in the mixture.HEMA has a boiling point and by carefully controlling distillation conditions it can be separated from the other components of the mixture. Other purification methods like extraction may also be used to remove impurities more effectively, ensuring a high - purity HEMA product suitable for various applications such as in the production of contact lenses, dental materials, and coatings.Purification methods such as extraction can be used to remove impurities. This ensures a high-purity HEMA product that is suitable for various applications, including the production of dental materials, coatings, and contact lenses.

What are the safety precautions when handling HEMA?

HEMA, or 2 - Hydroxyethyl Methacrylate, is a common monomer used in various industries, especially in the production of polymers for dental materials, contact lenses, and coatings.HEMA or 2 - Hydroxyethyl methacrylate is a monomer that is used in many industries, including the production of polymers, contact lenses and coatings. When handling HEMA, several safety precautions are necessary.HEMA handling requires several safety precautions.
First, in terms of personal protective equipment (PPE), appropriate clothing is essential.Clothing is a vital part of personal protective equipment. Workers should wear chemical - resistant clothing.Chemical-resistant clothing should be worn by workers. This could be a full - body suit made of materials that can withstand contact with HEMA without being degraded.This could be a body suit made from materials that are resistant to HEMA and will not degrade. Such suits prevent the chemical from coming into contact with the skin, which can cause irritation, redness, and allergic reactions.These suits prevent the chemical from contacting the skin which can cause irritations, redness and allergic reactions.

Eye protection is also crucial.Eye protection is equally important. Chemical - splash goggles should be worn at all times when handling HEMA.Wear chemical - splash goggles at all times while handling HEMA. Even a small splash of this monomer into the eyes can lead to significant discomfort, potential damage to the cornea, and long - term vision problems.Even a small splash can cause significant discomfort, corneal damage, and long-term vision problems.

Respiratory protection is another key aspect.Respiratory protection also plays a key role. If there is a risk of HEMA vapor or mist inhalation, workers should use respiratory devices.Workers should use respiratory protection if there is a danger of HEMA mist or vapor inhalation. For low - level exposure, a half - face respirator with appropriate cartridges can be sufficient.A half-face respirator with cartridges that are appropriate for low-level exposure can be sufficient. However, in areas with high - concentration vapors, a full - face respirator may be required.In areas with high concentrations of vapors a full-face respirator may be needed. Inhalation of HEMA can cause respiratory tract irritation, coughing, and in severe cases, difficulty in breathing.Inhaling HEMA can cause respiratory tract inflammation, coughing and, in severe cases of difficulty breathing.

In the workplace, proper ventilation is of utmost importance.Proper ventilation is essential in the workplace. HEMA should be handled in well - ventilated areas, preferably under a fume hood.HEMA should only be handled in well-ventilated areas, preferably with a fume hood. A fume hood effectively captures and exhausts any vapors or mists generated during the handling process, preventing their spread in the working environment.A fume hood is an effective way to capture and exhaust any vapors, mists or vapors that are generated during the handling procedure. This prevents their spread into the working environment.

Storage of HEMA also requires care.HEMA must also be stored with care. It should be stored in a cool, dry place away from sources of heat and ignition.It should be kept in a cool and dry place, away from heat sources and ignition sources. HEMA is flammable, so keeping it away from open flames, hot surfaces, and any potential ignition sources is vital to prevent fires and explosions.HEMA is flammable. It is important to keep it away from open fires, hot surfaces and other potential ignition sources. Additionally, storage containers should be tightly sealed to prevent leakage and evaporation.Storage containers should also be tightly sealed to avoid leakage and evaporation.

In case of accidental exposure, immediate action is necessary.Immediate action is required in the event of accidental exposure. If HEMA comes into contact with the skin, the affected area should be washed thoroughly with soap and water for at least 15 minutes.If HEMA is in contact with the skin for more than 15 minutes, wash the area thoroughly with soap and warm water. For eye contact, rinse the eyes with copious amounts of water for an extended period and seek immediate medical attention.If HEMA comes into contact with the eyes, wash them thoroughly for a long time using copious amounts water. Seek immediate medical attention. In case of inhalation, move the affected person to fresh air immediately and get medical help if symptoms such as coughing or shortness of breath persist.In the case of inhalation move the person to fresh air as soon as possible. Seek medical attention if symptoms like coughing or shortness-of-breath persist.