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Product Name | 2-Hydroxyethyl methacrylate phosphate |
Cas Number | 52628-03-2 |
Formula | C6H11O6P |
Molar Mass | 210.12 |
Density | 1.25 g/cm³ |
Boiling Point | Not available |
Melting Point | Not available |
Solubility | Soluble in water |
Viscosity | Not available |
Refractive Index | Not available |
Flash Point | Not available |
Ph | Not available |
Vapor Pressure | Not available |
Appearance | Clear liquid |
Odor | Mild |
What is the application of 2-Hydroxyethyl methacrylate phosphate?
2 - Hydroxyethyl methacrylate phosphate (HEMAP) has several important applications.2 - Hydroxyethyl Methacrylate Phosphate (HEMAP), has many important applications.
In the field of coatings, HEMAP is a valuable component.HEMAP is a very valuable component in the field of coatings. It can be incorporated into coating formulations to enhance properties like adhesion.It can be added to coating formulations to improve properties such as adhesion. The phosphate group in HEMAP can interact with various substrates, such as metals, plastics, and ceramics, forming strong chemical bonds.The phosphate group of HEMAP can interact strongly with substrates such as metals and plastics. This results in coatings that adhere well and are more resistant to peeling or flaking.This makes coatings more adherent and less likely to flake or peel. Additionally, it can improve the corrosion resistance of coatings on metal surfaces.It can also improve the corrosion resistance on metal surfaces. The phosphate functionality helps to passivate the metal, inhibiting the electrochemical reactions that lead to corrosion.The phosphate function helps to passivate metal surfaces, inhibiting electrochemical reactions which lead to corrosion. In automotive coatings, for example, HEMAP - containing coatings can provide long - lasting protection to the vehicle's body, maintaining its aesthetic appeal and structural integrity.In automotive coatings for example, HEMAP-containing coatings can provide long-lasting protection to the vehicle body, maintaining its structural integrity and aesthetic appeal.
HEMAP also plays a significant role in the dental materials industry.HEMAP plays a major role in the dental materials sector. It is used in the production of dental composites.It is used to produce dental composites. Dental composites need to bond effectively to tooth structures.Dental composites must bond well to tooth structures. The phosphate group in HEMAP can chelate with calcium ions present in teeth, facilitating strong adhesion.The phosphate in HEMAP can chelate calcium ions in teeth to facilitate strong adhesion. Moreover, HEMAP can contribute to the mechanical properties of dental composites.HEMAP also contributes to the mechanical properties in dental composites. It helps to improve the hardness and wear resistance of the composite, ensuring that dental restorations can withstand the forces of chewing over an extended period.It improves the hardness and wear-resistance of the composite to ensure that dental restorations are able to withstand the forces from chewing for a long period of time. This is crucial for the long - term success of dental treatments, as it reduces the need for frequent replacement of restorations.This is important for the long-term success of dental treatments as it reduces the frequency of replacement of restorations.
In the area of polymer - based adhesives, HEMAP is an important ingredient.HEMAP is a key ingredient in polymer-based adhesives. It can be copolymerized with other monomers to create adhesives with enhanced performance.It can be copolymerized to create adhesives that perform better. The presence of the phosphate group allows for better wetting of surfaces, enabling the adhesive to spread evenly and form a more intimate contact with the substrates.The presence of phosphate groups allows for better wetting surfaces, allowing the adhesive to spread more evenly and form an intimate contact with substrates. This leads to stronger adhesive bonds.This results in stronger adhesive bonds. These adhesives find applications in various industries, from electronics, where they are used to bond components, to packaging, where they help in sealing and joining different materials.These adhesives are used in many industries, including electronics, where they bond components, and packaging, where the adhesives help seal and join different materials.
In the realm of biomedical materials, HEMAP has potential uses.HEMAP is a biomedical material that has potential applications. Due to its ability to form cross - linked structures and its relatively biocompatible nature, it can be considered for applications such as tissue engineering scaffolds.It can be used for tissue engineering scaffolds due to its ability form cross-linked structures and its biocompatible nature. The phosphate groups might interact with biological molecules in the body, promoting cell adhesion and growth.The phosphate groups may interact with biological molecules within the body to promote cell adhesion and proliferation. This could potentially lead to the development of scaffolds that can support the regeneration of damaged tissues, providing a promising avenue for future biomedical research and treatments.This could lead to the creation of scaffolds which can support the regeneration and repair of damaged tissues.
What are the properties of 2-Hydroxyethyl methacrylate phosphate?
2 - Hydroxyethyl methacrylate phosphate, often abbreviated as HEMA - phosphate, has several notable properties.HEMA-phosphate is a 2 - Hydroxyethyl Methacrylate Phosphate with several notable properties.
Firstly, in terms of its chemical structure, it contains a phosphate group, which imparts certain characteristics.It has a phosphate molecule in its chemical structure. This molecule gives it certain characteristics. The phosphate group is polar, making the molecule hydrophilic to some extent.The phosphate group, which is polar in nature, makes the molecule to a certain extent hydrophilic. This hydrophilicity is significant as it can enhance the molecule's solubility in water - containing solvents.This hydrophilicity can be important as it can increase the molecule's soluble in water-containing solvents. It can also interact with other polar substances, like proteins or other biomolecules in biological systems, through electrostatic interactions.It can also interact through electrostatic interactions with other polar substances like proteins or biomolecules found in biological systems.
Secondly, the methacrylate part of the molecule provides polymerizability.Second, the methacrylate portion of the molecule is responsible for polymerizability. HEMA - phosphate can participate in polymerization reactions, typically radical - initiated polymerization.HEMA-phosphate can be involved in polymerization reactions. This property allows it to be incorporated into polymer networks.This property allows for its incorporation into polymer networks. When polymerized, it can contribute to the formation of cross - linked polymers.It can contribute to the creation of cross-linked polymers when polymerized. These polymers can have unique mechanical properties.These polymers may have unique mechanical properties. For example, the cross - linking can increase the hardness and durability of the resulting polymer material.Cross-linking can, for example, increase the durability and hardness of the polymer material.
The hydroxyl group in 2 - Hydroxyethyl methacrylate phosphate also plays an important role.The hydroxyl group also plays a significant role in 2 - Hydroxyethyl Methacrylate Phosphate. It can participate in hydrogen bonding.It can participate in hydrogen bonds. Hydrogen bonding can affect the physical properties of the molecule and its polymers.Hydrogen bonding affects the physical properties of a molecule and polymers. In solutions, it can influence the viscosity and intermolecular interactions.In solutions, hydrogen bonding can influence viscosity and the intermolecular interaction. In polymers, it can contribute to the formation of a more stable and ordered structure.In polymers, this can help to form a more ordered and stable structure.
In terms of biological properties, due to its relatively low toxicity and the ability to interact with biological components through the phosphate and hydroxyl groups, it has found applications in biomedical fields.It has applications in biomedical fields due to its biological properties. This is because of its low toxicity, and ability to interact with other biological components via the phosphate or hydroxyl groups. For instance, it can be used in the formulation of dental materials.It can be used to formulate dental materials. Its polymerizable nature allows for the creation of dental composites that can bond well to tooth structures, while its hydrophilicity helps in the initial wetting and adhesion processes.Its polymerizable properties allow for the creation dental composites which can bond well with tooth structures.
Furthermore, in coatings applications, 2 - Hydroxyethyl methacrylate phosphate can be used to formulate coatings with good adhesion properties.In addition, 2 - Hydroxyethyl Methacrylate Phosphate can be used in coatings to form coatings with excellent adhesion properties. The phosphate group can interact with various substrates, providing a strong bond between the coating and the surface.The phosphate group interacts with a variety of substrates to provide a strong bond between coating and surface. The polymerized form of HEMA - phosphate can also offer good chemical resistance, protecting the underlying substrate from environmental factors such as moisture, acids, and alkalis.The polymerized HEMA-phosphate can offer good chemical resistance and protect the underlying substrate against environmental factors like moisture, acids, or alkalis.
How is 2-Hydroxyethyl methacrylate phosphate synthesized?
2 - Hydroxyethyl methacrylate phosphate can be synthesized through the following general steps:The following general steps can be used to synthesize 2 - Hydroxyethyl Methacrylate Phosphate:
Reagents and Materials PreparationReagents & Materials Preparation
First, gather the necessary starting materials.Gather the materials you need to start. Hydroxyethyl methacrylate (HEMA) is a key monomer.Hydroxyethyl Methacrylate (HEMA), a key monomer, is required. Phosphorus - containing reagents such as phosphoric acid or phosphoryl chloride are also required.Also required are phosphorus-containing reagents, such as phosphoric or phosphoryl acid. Appropriate solvents like dichloromethane or toluene might be used depending on the reaction method, and catalysts such as triethylamine may be needed to facilitate the reaction.Depending on the method of reaction, dichloromethane and toluene may be used. Triethylamine or other catalysts might also be required to facilitate the process.
Reaction with Phosphoryl Chloride (One Common Method)Reaction with Phosphoryl Chloride: One Common Method
In a reaction vessel, under an inert gas atmosphere (such as nitrogen) to prevent oxidation, add a certain amount of HEMA.Add a small amount of HEMA to a reaction vessel under an inert atmosphere (such a nitrogen) to prevent the oxidation. Then, slowly add phosphoryl chloride drop - by - drop with continuous stirring.Add phosphoryl chloride slowly, drop by drop, while stirring continuously. The reaction is exothermic, so temperature control is crucial.Temperature control is important because the reaction is exothermic. Usually, the reaction is carried out at a relatively low temperature initially, around 0 - 10 degC.The reaction is usually carried out initially at a low temperature, between 0 and 10 degC. The phosphoryl chloride reacts with the hydroxyl group of HEMA.The phosphoryl group of HEMA reacts with phosphoryl chloride. The chemical reaction can be represented in a simplified way as: HEMA + POCl3 - intermediate product.The chemical reaction is represented in a simple way as HEMA + POCl3- intermediate product. During this process, hydrogen chloride gas is evolved as a by - product, which should be properly vented and trapped.During the process, hydrogen chloride is produced as a by-product, which must be vented and trapped.
Neutralization Step
After the addition of phosphoryl chloride is complete, the reaction mixture is allowed to warm up to room temperature and stirred for a certain period to ensure complete reaction.After adding the phosphoryl chloride, the reaction mixture must be allowed to warm to room temperature. It is then stirred for some time to ensure a complete reaction. Then, a base such as triethylamine is added to neutralize the hydrogen chloride generated in the reaction.Triethylamine or another base is then added to neutralize any hydrogen chloride produced during the reaction. The triethylamine reacts with hydrogen chloride to form an ammonium salt, which can be removed by filtration or extraction later.Triethylamine reacts to hydrogen chloride and forms an ammonium sulfate, which can then be removed later by filtration or extracting.
Purification Process
The crude product obtained after neutralization contains unreacted starting materials, by - products, and the desired 2 - Hydroxyethyl methacrylate phosphate.The crude product obtained following neutralization contains unreacted materials, by-products, and the desired 2- Hydroxyethylmethacrylate phosphate. Purification can be achieved through several methods.Purification can be achieved by a variety of methods. Liquid - liquid extraction is often used.Liquid-liquid extraction is a common method. For example, the reaction mixture can be extracted with an organic solvent (such as ethyl acetate) and an aqueous solution.For example, a reaction mixture can extracted using an organic solvent (such ethyl-acetate) and aqueous solutions. The product will partition between the two phases, and through multiple extractions, impurities can be separated.The product will partition into the two phases and impurities can then be separated through multiple extractions. Column chromatography can also be employed for further purification.For further purification, column chromatography is also an option. The product is loaded onto a chromatography column filled with an appropriate stationary phase (such as silica gel), and eluted with a suitable mobile phase to obtain pure 2 - Hydroxyethyl methacrylate phosphate.The product is loaded on a chromatography columns filled with an appropriate stationary (such as silica) and eluted using a suitable mobile phase, to obtain pure 2-hydroxyethyl-methacrylate-phosphate.
Characterization
Once the purification is complete, the synthesized product is characterized.After purification, the synthesized products are characterized. Techniques like nuclear magnetic resonance (NMR) spectroscopy can be used to confirm the structure of the product by analyzing the chemical shifts and coupling constants of the hydrogen and phosphorus atoms in the molecule.Nuclear magnetic resonance (NMR spectroscopy) can be used to confirm a product's structure by analyzing the chemical shifting and coupling constants between the hydrogen and the phosphorus atoms. Fourier - transform infrared (FT - IR) spectroscopy can identify the functional groups present, such as the carbon - carbon double bond of methacrylate, the phosphate group, and the remaining hydroxyl group.Fourier – transform infrared spectroscopy (FT – IR) can identify functional groups, such as the double carbon-carbon bond of the methacrylate molecule, the phosphate atoms, and the remaining hydroxyl atoms. Mass spectrometry can determine the molecular weight of the compound, providing further evidence for the successful synthesis of 2 - Hydroxyethyl methacrylate phosphate.Mass spectrometry is a powerful tool for determining the molecular mass of the compound. This provides further evidence of the successful synthesis.
What are the safety precautions when handling 2-Hydroxyethyl methacrylate phosphate?
2 - Hydroxyethyl methacrylate phosphate is a chemical compound that requires certain safety precautions during handling.2 - Hydroxyethyl Methacrylate Phosphate is a chemical that requires special precautions when handling.
Firstly, personal protective equipment (PPE) is essential.First, it is important to have the right personal protective equipment. Wear appropriate chemical - resistant gloves, such as those made of nitrile or neoprene.Wear gloves that are resistant to chemicals, such as those made from nitrile and neoprene. These gloves can prevent skin contact, which can lead to irritation, allergic reactions, or potential absorption of the chemical into the body.These gloves can protect the skin from contact with chemicals, which could cause irritation, allergic reactions or absorption into the body. Additionally, use safety goggles or a face shield to protect the eyes.Use safety goggles, or a face shield, to protect your eyes. Splashes of 2 - Hydroxyethyl methacrylate phosphate can cause serious eye damage, including irritation, redness, and in severe cases, loss of vision.Splashes of 2-Hydroxyethyl-methacrylate-phosphate can cause serious damage to the eyes, including irritation, stinging, and, in severe cases, vision loss.
Secondly, ensure proper ventilation in the handling area.Second, ensure that the area where you are handling the chemical is properly ventilated. This chemical may emit vapors that can be harmful if inhaled.This chemical can emit vapors which are harmful if inhaled. A well - ventilated space, preferably with local exhaust ventilation, helps to remove these vapors from the breathing zone.This chemical can emit vapors that are harmful if inhaled. A well-ventilated space, preferably one with local exhaust ventilation will help to remove the vapors. Inhalation of the vapors can cause respiratory tract irritation, coughing, shortness of breath, and potentially more serious respiratory problems over time.Inhalation can cause respiratory tract irritation and shortness of breathe.
When storing 2 - Hydroxyethyl methacrylate phosphate, keep it in a cool, dry place away from sources of heat and ignition.Store 2 - Hydroxyethyl Methacrylate Phosphate in a cool and dry place, away from heat sources and ignition. It is flammable under certain conditions, so avoid storing it near open flames, hot surfaces, or other ignition sources.It can be flammable in certain conditions. Avoid storing it near flames, hot surfaces or other ignition sources. Also, store it in a tightly sealed container to prevent leakage and evaporation.Store it in a tightly-sealed container to prevent leaking and evaporation.
In case of skin contact, immediately remove any contaminated clothing and wash the affected area thoroughly with soap and water for at least 15 minutes.If skin contact occurs, remove all contaminated clothing immediately and wash the affected area thoroughly in soap and water for 15 minutes. Seek medical attention if irritation persists. For eye contact, flush the eyes with copious amounts of water for at least 15 minutes, lifting the eyelids occasionally to ensure complete rinsing, and then seek immediate medical help.If you have eye contact, rinse your eyes for at least 15 mins with plenty of water, lifting your eyelids periodically to ensure that the entire eye is rinsing. Then seek immediate medical attention. If inhaled, move to fresh air immediately.If inhaled, get to fresh air as soon as possible. If breathing is difficult, provide oxygen and call for medical assistance.If breathing is difficult, call for medical help and provide oxygen.
Finally, be aware of the potential environmental impacts.Be aware of any potential environmental impact. Avoid releasing 2 - Hydroxyethyl methacrylate phosphate into the environment.Avoid releasing 2 – Hydroxyethyl Methacrylate Phosphate into the environment. In case of spills, contain the spill area to prevent the spread of the chemical.Contain the spilled area to prevent the chemical from spreading. Use appropriate absorbent materials to clean up the spill, and dispose of the contaminated materials according to local regulations.Use absorbent materials to clean the spill and dispose of the contaminated material according to local regulations.
What are the storage requirements for 2-Hydroxyethyl methacrylate phosphate?
2 - Hydroxyethyl methacrylate phosphate is a chemical compound with specific storage requirements to ensure its stability, safety, and quality.2 - Hydroxyethyl Methacrylate Phosphate is a chemical compound that has specific storage requirements in order to ensure its quality, safety, and stability.
Firstly, storage should be in a cool and dry place.First, the storage place should be cool and dry. High temperatures can accelerate chemical reactions and potentially cause decomposition or polymerization of 2 - Hydroxyethyl methacrylate phosphate.High temperatures can speed up chemical reactions, and cause the decomposition or polymerization 2 - Hydroxyethyl Methacrylate Phosphate. A temperature range between 2 - 8degC is often ideal for long - term storage.Temperatures between 2 and 8degC are ideal for long-term storage. This helps to slow down any potential degradation processes that could be temperature - dependent.This can help to slow down any possible degradation processes that are temperature-dependent. For instance, heat can cause the molecule to break down into its components or initiate self - polymerization, which would render the compound useless for its intended applications such as in coatings, adhesives, or dental materials.Heat can cause a molecule to break into its constituents or initiate self-polymerization. This would render the compound unusable for its intended application, such as in dental materials, coatings, adhesives or dental materials.
Secondly, it should be stored away from direct sunlight and sources of strong radiation.Second, it should not be exposed to direct sunlight or sources of strong radiation. Ultraviolet light from sunlight or other radiation sources can also trigger photochemical reactions.Photochemical reactions can be triggered by ultraviolet light from sunlight and other radiation sources. These reactions may lead to changes in the chemical structure of 2 - Hydroxyethyl methacrylate phosphate.These reactions can lead to changes in 2 - Hydroxyethyl Methacrylate Phosphate's chemical structure. It can cause bond cleavage or rearrangement, altering its physical and chemical properties.It can cause bond cleavage and rearrangement altering the physical and chemical properties. To prevent this, storing the compound in opaque containers or in a storage area with limited light exposure is crucial.To prevent this from happening, it is important to store the compound in opaque containers and in an area with limited exposure to light.
Thirdly, the storage environment should be well - ventilated.Thirdly, it is important that the storage area be well-ventilated. This is important because if there is any leakage or evaporation of 2 - Hydroxyethyl methacrylate phosphate, proper ventilation can help to disperse the vapors.Proper ventilation is necessary to disperse vapors if 2 - Hydroxyethyl Methacrylate Phosphate is leaking or evaporating. The compound may emit fumes that could be harmful if they accumulate in a confined space.The compound can emit fumes which could be harmful in a confined area. Good ventilation also helps to maintain a consistent temperature and humidity level in the storage area.A good ventilation system will also help to maintain a constant temperature and humidity in the storage area.
Fourthly, the storage containers must be carefully selected.The storage containers should be carefully chosen. They should be made of materials that are chemically compatible with 2 - Hydroxyethyl methacrylate phosphate.They should be made from materials that are compatible with 2 – Hydroxyethyl Methacrylate Phosphate. For example, certain plastics or metals may react with the compound.Certain plastics and metals, for example, may react with the compound. Glass containers are often a good choice as they are relatively inert and can provide a good barrier against air, moisture, and light.Glass containers are a popular choice because they are relatively inert, and can act as a barrier against moisture, air, and light. The containers should also be tightly sealed to prevent moisture ingress and evaporation of the compound.Containers should be tightly sealed to avoid moisture intrusion and evaporation. Moisture can react with 2 - Hydroxyethyl methacrylate phosphate, potentially causing hydrolysis reactions that can change its composition.Moisture can react 2 - Hydroxyethyl Methacrylate Phosphate, causing hydrolysis reactions which can change its composition.
Finally, it is essential to store 2 - Hydroxyethyl methacrylate phosphate away from incompatible substances.It is important to keep 2 - Hydroxyethyl Methacrylate Phosphate away from substances that are incompatible. Substances such as strong acids, bases, oxidizing agents, and reducing agents can react violently with it.Substances like strong acids, bases and oxidizing and reducing agents are able to react violently. For example, an oxidizing agent could oxidize the organic components of 2 - Hydroxyethyl methacrylate phosphate, leading to a loss of its desired properties.An oxidizing agent, for example, could oxidize organic components in 2 - Hydroxyethyl Methacrylate Phosphate, resulting in a loss of desired properties. By following these storage requirements, the integrity of 2 - Hydroxyethyl methacrylate phosphate can be maintained for an extended period.By following these storage instructions, the integrity of 2-Hydroxyethyl-methacrylate-phosphate can be preserved for a long period.